Lentinan

09/01/2010 - "These findings demonstrate that the combination of Lentinan and S-1 is effective against OSCC and has the potential of being a new therapeutic tool for future treatment of these tumors."
11/01/1984 - "When DBA/2 mice were used, lentinan was also effective for even autochthonous primary tumors induced within 15 weeks after MC inoculation, but less effective for tumors induced during the 16 to 36 weeks after MC treatment. "
01/01/2007 - "[Study on effect of lentinan in enhancing anti-tumor action of dendritic cytoma vaccine and its mechanism]."
01/01/1998 - "This study confirms, in Caucasian subjects also, the good tolerability of lentinan observed in Japanese cancer patients. "
03/01/1988 - "C3H/He mice transplanted syngeneic MM102 tumor subcutaneously in the footpad were used to study the timing of administration of lentinan when combined with local irradiation of X-ray. "

07/01/1999 - "Lentinan is considered to prolong survival and improved quality of life when gastric cancer patients with unresectable or recurrent diseases are treated in combination with other chemotherapeutic agents."
01/01/1987 - "Clinical efficacy of lentinan on patients with stomach cancer: end point results of a four-year follow-up survey."
04/01/1988 - "(5) Clinically, a randomized study of advanced or recurrent gastric cancer patients treated with MMC and FT(MF) with or without Lentinan was performed. "
04/01/1988 - "In addition, a clinical randomized study of advanced or recurrent gastric cancer patients treated with MMC and FT(MF) with or without lentinan was performed. "
04/01/1986 - "A clinical randomized study of advanced and recurrent gastric cancer patients treated with MMC and FT (MF) with or without LENTINAN, was then performed. "

07/01/1985 - "In particular, combination therapy with TNF and lentinan was very effective against MH134 hepatoma without having detectable side-effects, showing that lentinan expanded the therapeutical potential of TNF. "
03/01/2009 - "A superfine dispersed lentinan-containing supplementary food is effective for hepatocellular carcinoma patients' survival. "
03/01/2009 - "Clinical efficacy of superfine dispersed lentinan (beta-1,3-glucan) in patients with hepatocellular carcinoma."
03/01/2009 - "We investigated the effectiveness of supplementary food containing superfine dispersed lentinan (beta-1,3-glucan) in patients with unresectable or recurrent hepatocellular carcinoma in a multi-center study. "
07/01/1982 - "[Antitumor effect of polysaccharide lentinan on C3H/He mice bearing MH134 ascites hepatoma]."

07/01/2009 - "Additionally, lentinan was possibly more effective in patients with lymph-node metastasis than in non-node metastasis patients (P for interaction=0.077). "
02/01/2000 - "After operation, administrations of UFT 300 mg/day and lentinan 2 mg/2 weeks were given, and the hepatic metastasis disappeared by 17 months. "
05/01/1988 - "Furthermore, we studied the effect of combination therapy of UFT and lentinan (1 mg/kg/day i.p.) on the metastasis of SST-2 cells after surgical excision of the primary sites. "
01/01/1987 - "The antitumor and metastasis-inhibitory activities, mode of action, and clinical application of lentinan, a strictly purified beta-1,6:beta-1,3-glucan, are reviewed. "
01/01/1987 - "Antitumor and metastasis-inhibitory activities of lentinan as an immunomodulator: an overview."

02/01/1982 - "Combined treatment with lentinan and LPS was very effective against Ehrlich carcinoma in ddY mice, and the syngeneic mammary carcinoma MM46 in C3H/He mice. "
03/01/2012 - "Combination therapy with lentinan improves outcomes in patients with esophageal carcinoma."
10/01/2002 - "Further investigation on the effectiveness of the extracted lentinan was then performed using human colon-carcinoma cell lines in mice. "
10/01/2002 - "Inhibition of human colon carcinoma development by lentinan from shiitake mushrooms (Lentinus edodes)."
02/01/1994 - "[Effect of lentinan for advanced prostate carcinoma]."