An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma.
Also Known As:
Lecithin Cholesterol Acyltransferase; Acyltransferase, Lecithin Cholesterol; Cholesterol Ester Lysolecithin Acyltransferase; Lecithin Acyltransferase; Phosophatidylcholine-Sterol Acyltransferase; Acyltransferase, Lecithin; Acyltransferase, Phosophatidylcholine-Sterol; Cholesterol Acyltransferase, Lecithin; O-Acyltransferase, Phosphatidylcholine-Sterol; Phosophatidylcholine Sterol Acyltransferase; Phosphatidylcholine Sterol O Acyltransferase; Phosphatidylcholine:sterol O-acyltransferase