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Lactalbumin (alpha-Lactalbumin)

Subscribe to New Research on Lactalbumin

Also Known As:

alpha-Lactalbumin; alpha-Lactalbumin A; alpha-Lactalbumin B; alpha-Lactalbumin C; A, alpha-Lactalbumin; B, alpha-Lactalbumin; C, alpha-Lactalbumin; alpha Lactalbumin; alpha Lactalbumin A; alpha Lactalbumin B; alpha Lactalbumin C; Lactalbumins

Networked: 284 relevant articles (8 outcomes, 21 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Dietary Proteins: 1551
    - Milk Proteins: 1092
      - Lactalbumin: 284
        apo-alpha-lactalbumin: 2
        dansyl alpha-lactalbumin
        human HAMLET complex
        pre-alpha-lactalbumin
  - Albumins: 151
    - Lactalbumin: 284

Experts

1.	Svanborg, Catharina: 30 articles (05/2015 - 01/2003)
2.	Mossberg, Ann-Kristin: 19 articles (01/2011 - 01/2003)
3.	Gustafsson, Lotta: 10 articles (03/2009 - 01/2003)
4.	Permyakov, Eugene A: 6 articles (09/2013 - 05/2004)
5.	Trulsson, Maria: 5 articles (10/2012 - 01/2009)
6.	Hallgren, Oskar: 5 articles (03/2009 - 01/2003)
7.	Linse, Sara: 5 articles (11/2005 - 01/2003)
8.	Nadeem, Aftab: 4 articles (05/2015 - 10/2012)
9.	Storm, Petter: 4 articles (01/2014 - 01/2009)
10.	Permyakov, Sergei E: 4 articles (09/2013 - 12/2008)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2015 - "This view emerges from the extraordinary manner in which HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) kills a wide range of tumor cells in vitro and demonstrates therapeutic efficacy and selectivity in cancer models and clinical studies. " 12/30/2015 - "Therefore, in this study, we prepared self-assembled α-lactalbumin that exhibits strong inherent antiproliferative potential in multiple cancer cells which can be used for efficient therapeutic approach in cancer. " 11/01/2015 - "The HAMLET family of compounds (Human Alpha-lactalbumin Made Lethal to Tumours) was discovered during studies on the properties of human milk, and is a class of protein-lipid complexes having broad spectrum anti-cancer, and some specific anti-bacterial properties. " 05/01/2004 - "This study tested the effect of HAMLET (human alpha-lactalbumin made lethal to tumor cells) on mammary cells. " 12/30/2015 - "When compared with a well-known protein-based anticancer agent BAMLET (bovine α-lactalbumin made lethal against tumor cell), the self-assembled BLA clearly exhibited higher cytotoxicity to cancer cells than BAMLET. "
2.	Breast Neoplasms (Breast Cancer) 07/01/2010 - "Thus, alpha-lactalbumin vaccination may provide safe and effective protection against the development of breast cancer for women in their post-child-bearing, premenopausal years, when lactation is readily avoidable and risk for developing breast cancer is high." 12/01/2005 - "AdE1aALAE1b showed better breast cancer-restricted replication than AdALAE1a, suggesting that a transcriptional targeting modality with alpha-lactalbumin promoter controlling both E1a and E1b gene expression is superior to alpha-lactalbumin promoter controlling only E1a gene expression. " 10/15/1980 - "These findings suggest that IIF for alpha-lactalbumin may be helpful in ascertaining the site of origin of metastatic breast tumors. " 12/01/2005 - "Alpha-lactalbumin promoter showed significantly higher activity in MDA-MB-435S and T47D breast cancer cells than in normal breast cell lines or other tumor cell lines. " 12/01/2005 - "To evaluate the effect of gene therapy for breast cancer by controlling adenovirus replication with human alpha-lactalbumin promoter, we investigated the activity of a 762-bp human alpha-lactalbumin promoter. "
3.	Weight Loss (Weight Reduction) 06/01/1997 - "However, the test group regained the weight loss after switching to the lactalbumin diet. " 02/01/2011 - "Efficacy of α-lactalbumin and milk protein on weight loss and body composition during energy restriction." 08/01/2009 - "Weight loss by energy restriction was performed on four different high-Ca diets (1.8 % CaCO3) containing different whey proteins (18 % of energy): alpha-lactalbumin (ALA), beta-lactoglobulin (BLG), lactoferrin (LF) and whey protein isolate (WPI). "
4.	Milk Hypersensitivity (Milk Allergy) 03/01/1991 - "No correlation was found between concentrations of serum IgE and serum alpha-lactalbumin in the children with cows' milk allergy." 06/01/1996 - "The results of this study demonstrate the existence of an IgE-mediated mare's milk allergy caused by low molecular weight heat-labile proteins, most likely alpha-lactalbumin and beta-lactoglobulin, which do not cross-react with the corresponding whey proteins in cow's milk." 12/23/2015 - "α-Lactalbumin and β-lactoglobulin are two major whey proteins that specifically bind immunoglobulin E and are suspected as major allergens causing cow's milk allergy (CMA). " 07/01/2008 - "To investigate the intrinsic properties (as well as the effect of pasteurization) of the milk proteins alpha-lactalbumin, beta-lactoglobulin and casein that promote the induction of milk allergy. " 01/01/2006 - "Prospectively, 45 infants and toddlers with a positive history of cow's milk allergy confirmed by positive skin prick test and high IgE levels for either alpha-lactalbumin, beta-lactoglobulin, or casein and positive single-blind food challenge received extensively hydrolyzed milk formulas for 1 year. "
5.	Carcinoma (Carcinomatosis) 07/01/2010 - "We selected alpha-lactalbumin as our target vaccine autoantigen because it is a breast-specific differentiation protein expressed in high amounts in the majority of human breast carcinomas and in mammary epithelial cells only during lactation. " 08/01/1999 - "The influence of the ON on the activity of the cytotoxic fraction of human milk alpha-lactalbumin towards human mammary gland carcinoma MCF-7 cells was studied. " 07/01/1998 - "Lactalbumin-positive mammary carcinoma in a mare." 07/01/1992 - "Immunohistochemical staining showed alpha-lactalbumin (alpha-LA) in the lipid-secreting carcinomas at sites exhibiting active lipid secretion. " 03/01/1989 - "In addition, GCDFP-15 was compared with another putative mammary epithelial marker, alpha-lactalbumin (ALA), with respect to sensitivity and specificity for a diagnosis of breast carcinoma. "

Related Drugs and Biologics

1.	Oleic Acid (Oleate)
2.	Lactoferrin
3.	Milk Proteins (Milk Protein)
4.	sunitinib (Sutent)
5.	Caseins (Casein)
6.	Proteins (Proteins, Gene)
7.	Lactoglobulins (beta-Lactoglobulin)
8.	Antibodies
9.	Immunoglobulin E (IgE)
10.	Bovine Serum Albumin

Related Therapies and Procedures

1.	Protein-Restricted Diet (Diet, Protein Restricted)
2.	Investigational Therapies (Experimental Therapy)
3.	Heterologous Transplantation (Xenotransplantation)
4.	Photochemotherapy (Photodynamic Therapy)
5.	Subcutaneous Injections