Lacrimal Duct Obstruction

Interference with the secretion of tears by the lacrimal glands. Obstruction of the lacrimal sac or nasolacrimal duct causing acute or chronic inflammation of the lacrimal sac (DACRYOCYSTITIS). It is caused also in infants by failure of the nasolacrimal duct to open into the inferior meatus and occurs about the third week of life. In adults occlusion may occur spontaneously or after injury or nasal disease. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p250)

Also Known As:

Networked: 28 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Ectodermal Dysplasia (Aplasia Cutis Congenita)
2.	Hearing Loss (Hearing Impairment)
3.	Lacrimal Apparatus Diseases (Epiphora)
4.	Cleft Lip (Harelip)
5.	Strabismus (Squint)

Experts

1.	Basu, Sumit Kumar: 1 article (10/2015)
2.	Ghosh, Debangshu: 1 article (10/2015)
3.	Saha, Somnath: 1 article (10/2015)
4.	Oka, Yutaro: 1 article (01/2015)
5.	Shimizu, Yoshihiro: 1 article (01/2015)
6.	Kinoshita, Shigeru: 1 article (01/2015)
7.	Yokoi, Norihiko: 1 article (01/2015)
8.	Wakimasu, Koichi: 1 article (01/2015)
9.	Mitani, Takuya: 1 article (01/2015)
10.	Selva, Dinesh: 1 article (01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lacrimal Duct Obstruction:

1.	SiliconesIBA 09/01/2005 - "In our study, dacryoscintigraphy results of patients with functional lacrimal duct obstruction are newly classified into three types, the effects and prognoses of silicone tube intubation are noted according to each type, and the role of dacryoscintigraphy in determining appropriate surgical approaches is evaluated. " 09/01/2005 - "Impression of functional lacrimal duct obstruction was made through dacryoscintigraphy, and silicone tubes were inserted. " 05/01/1997 - "[Silicone intubation--treatment of complicated conditions of congenital lacrimal duct obstruction]." 06/01/1988 - "Silicone intubation for the treatment of congenital lacrimal duct obstruction: successful results removing the tubes after six weeks." 01/01/2003 - "[Significance of the fluorescein dye disappearance test (FDDT) in the removal of the silicone cannula and prognosis in congenital lacrimal duct obstruction]."
2.	EctrodactylyIBA 01/01/2013 - "A case with R304W mutation, characterized by the presence of all major (ectrodactyly, ectodermal dysplasia, cleft lip and palate) and two minor (lacrimal duct obstruction, developmental delay) clinical symptoms of the syndrome is presented. " 11/01/2004 - "He had ectrodactyly and missing middle fingers bilaterally, onychodysplasia, hypodontia with missing teeth, hypohidrosis and lacrimal duct obstruction. " 01/01/2009 - "Ectrodactyly-ectodermal dysplasia-clefting (EEC) syndrome is characterized by ectodermal dysplasia, ectrodactyly and facial clefting with multiple congenital anomalies such as urinary tract anomaly, lacrimal duct obstruction, and hearing loss. " 01/01/2012 - "EEC syndrome is characterized by ectodermal dysplasia, ectrodactyly and cleft lip and/or palate and associated anomalies such as lacrimal duct obstruction, urinary tract anomaly, and hearing loss. "
3.	Ectrodactyly-cleft lip/palate syndromeIBA 01/01/2009 - "Ectrodactyly-ectodermal dysplasia-clefting (EEC) syndrome is characterized by ectodermal dysplasia, ectrodactyly and facial clefting with multiple congenital anomalies such as urinary tract anomaly, lacrimal duct obstruction, and hearing loss. " 01/01/2012 - "EEC syndrome is characterized by ectodermal dysplasia, ectrodactyly and cleft lip and/or palate and associated anomalies such as lacrimal duct obstruction, urinary tract anomaly, and hearing loss. "
4.	Fluorescein (Funduscein)FDA LinkGeneric 01/01/2003 - "[Significance of the fluorescein dye disappearance test (FDDT) in the removal of the silicone cannula and prognosis in congenital lacrimal duct obstruction]."
5.	SiliconIBA 01/01/1985 - "Therefore a conservatively unsuccessfully treated lacrimal duct obstruction in infants should be followed by high pressure irrigation and if necessary by silicon intubation of the lacrimal system."
6.	Polyurethanes (Polyurethane)IBA 06/01/2003 - "To analyze a series of patients with lacrimal duct obstruction treated with polyurethane stents. "
7.	IodineIBA 03/01/2012 - "Radioactive iodine uptake by nasolacrimal duct mucosa with subsequent inflammation, edema and fibrosis seems to have a relationship to lacrimal duct obstruction. "
8.	Antineoplastic Agents (Antineoplastics)IBA 01/01/2015 - "In recent years, the incidence of adverse ocular reactions, including corneal problems and lacrimal duct obstruction, due to antineoplastic agents such as S-1 has increased. "
9.	Adrenal Cortex Hormones (Corticosteroids)IBA 01/01/1962 - "CORTICOSTEROIDS AND FIBROLYSIN IN THE PREVENTION OF LACRIMAL DUCT OBSTRUCTION."
10.	capecitabine (Xeloda)FDA Link 01/01/2015 - "We believe that reporting this case could be valuable in discussing capecitabine-induced lacrimal duct obstruction." 01/01/2015 - "In this case, lacrimal duct obstruction likely developed due to capecitabine. " 01/01/2015 - "This report describes our recent experience with a case of lacrimal duct obstruction caused by capecitabine. " 01/01/2015 - "[A case of lacrimal duct obstruction caused by capecitabine]."

Therapies and Procedures

1.	Dacryocystorhinostomy 07/01/2009 - "For almost a century external dacryocystorhinostomy was the gold standard for correction of lacrimal duct obstruction. " 10/01/1999 - "Naso-lacrimal duct dilatation and stenting is a viable alternative to conventional dacryocystorhinostomy in the treatment of naso-lacrimal duct obstruction and merits a larger trial." 07/01/2014 - "Dacryocystorhinostomy (DCR) is performed in patients with saccal or postsaccal lacrimal duct obstruction. " 09/01/2007 - "Eleven cases of recurrent lacrimal duct obstruction after external dacryocystorhinostomy were submitted to endoscopic dacryocystorhinostomy. " 09/01/2007 - "To observe the benefit of endoscopic surgery for the treatment of lacrimal duct obstruction in revisional surgeries after external dacryocystorhinostomy. "
2.	Stents 10/01/2009 - "[Treatment of lacrimal duct obstruction with a Tear-Leader stent]." 06/01/2003 - "[Lacrimal duct obstruction treated with lacrimonasal stent]." 10/01/1999 - "This pilot project aimed to evaluate the use of stents as an alternative approach to the treatment of naso-lacrimal duct obstruction. " 06/01/2003 - "To analyze a series of patients with lacrimal duct obstruction treated with polyurethane stents. "
3.	Catheters 09/01/2009 - "Balloon-catheter dilatation is an efficient and safe procedure and might be used for congenital lacrimal duct obstruction treatment in children older than 2 years." 09/01/2009 - "Children between 2 and 5 years old, with congenital lacrimal duct obstruction, were treated with balloon-catheter dilatation (Lacricath). " 09/01/2009 - "To verify the results of balloon-catheter dilatation for the treatment of congenital lacrimal duct obstruction. " 01/01/2003 - "[Significance of the fluorescein dye disappearance test (FDDT) in the removal of the silicone cannula and prognosis in congenital lacrimal duct obstruction]."
4.	Blepharoplasty 01/01/2015 - "Forty-three eyes of 27 patients with blepharoptosis and 29 eyes of 18 patients with dermatochalasis without lacrimal duct obstruction or other eyelid diseases underwent anterior approach levator advancement or blepharoplasty. "
5.	Sutures (Suture) 01/01/1984 - "The propositus was a 16-month-old caucasian male with 1) mental retardation, 2) congenital microcephaly, 3) postnatal growth deficiency, 4) ridged metopic suture with narrow bifrontal diameter, 5) upslanted palpebral fissures with persistent epicanthal folds, strabismus, and lacrimal duct obstruction, 6) narrow palate, 7) macrodontia, 8) anteverted ears, 9) atrial septal defect, 10) dry brittle scalp hair and 11) cutis marmorata. "