Vulvar Lichen Sclerosus

10/01/2001 - "Clobetasol propionate was an effective treatment of premenarchal vulvar lichen sclerosus in this small group; however, recurrences were common and required additional steroid treatment. "
06/01/2004 - "To analyze the rates of remission, recurrence, and chronic evolution of vulvar lichen sclerosus (VLS) treated with 0.05% clobetasol propionate ointment and determine whether this treatment can decrease the risk of malignant evolution. "
01/01/2011 - "This study investigates the health-related quality of life in patients with vulvar lichen sclerosus (LS) and the patient-defined therapeutic benefit of clobetasol. "
01/01/2002 - "Clobetasol propionate 0.05% has been the mainstay in treating vulvar lichen sclerosus (VLS) for the past ten years. "
01/01/2002 - "Vulvar lichen sclerosus in postmenopausal women: a comparative study for treating advanced disease with clobetasol propionate 0.05%."

12/01/2015 - "Topical corticosteroids are the first-line treatment for vulvar lichen sclerosus (VLS). "
04/01/2015 - "Treatment of vulvar lichen sclerosus (VLS) in children by topical corticosteroids gives control of symptoms and some resolution of physical signs, but large studies are limited. "
04/01/2015 - "Treatment of vulvar lichen sclerosus with topical corticosteroids in children: a study of 72 children."
06/01/2015 - "Limited evidence is available on the effectiveness of treatments alternative to corticosteroids for vulvar lichen sclerosus (VLS). "
07/01/2014 - "Vulvar lichen sclerosus is a chronic condition usually responsive to topical corticosteroids. "

01/01/1998 - "Shortly before planned surgical exploration, the clinical finding of an extensive vulvar lichen sclerosus pointed towards a possible long-term use of testosterone-containing cremes for symptomatic relief of this disease. "
02/01/1997 - "To evaluate the systemic and therapeutic effect of topical testosterone treatment in vulvar lichen sclerosus. "
02/01/1997 - "Short-term effects of topical testosterone in vulvar lichen sclerosus."
07/01/1994 - "Topical testosterone in the treatment of vulvar lichen sclerosus."
01/01/1991 - "Topical testosterone is recognized as a standard treatment for vulvar lichen sclerosus et atrophicus. "

02/01/2004 - "Pimecrolimus may be an effective treatment of vulvar lichen sclerosus. "
10/01/2004 - "In this small series, pimecrolimus appeared to be a safe and effective treatment of vulvar lichen sclerosus. "
02/01/2010 - "The effect of topical pimecrolimus on inflammatory infiltrate in vulvar lichen sclerosus."
10/01/2009 - "Altered p53 and Bcl-2 expression in keratinocytes of vulvar lichen sclerosus during pimecrolimus treatment."
05/01/2007 - "Pimecrolimus 1% cream in the treatment of vulvar lichen sclerosus in postmenopausal women."

07/01/1999 - "To assess the efficacy of graduated topical steroids for long-term maintenance therapy for vulvar lichen sclerosus. "
06/01/2004 - "To record the clinical features, symptomatic response to topical steroids, and resolution of clinical signs in a large cohort of female patients with vulvar lichen sclerosus. "
11/01/1999 - "Symptomatic remission was significantly easier to achieve in patients with vulvar lichen sclerosus as compared to those with squamous cell hyperplasia following treatment with graduated topical steroids."
11/01/1999 - "To determine whether symptomatic remission could be obtained equally effectively in patients with vulvar lichen sclerosus, squamous cell hyperplasia or mixed disease in response to a standardized course of graduated topical steroids. "
11/01/1999 - "Response of vulvar lichen sclerosus and squamous cell hyperplasia to graduated topical steroids."

12/01/2015 - "Continuous vs. tapering application of the potent topical corticosteroid mometasone furoate in the treatment of vulvar lichen sclerosus: results of a randomized trial."
07/01/2014 - "Mometasone fuoroate 0.1% ointment in the treatment of vulvar lichen sclerosus: a study of efficacy and safety on a large cohort of patients."
01/01/2015 - "Growing evidence for topical mometasone fuoroate in the treatment of Vulvar Lichen Sclerosus."
06/01/2003 - "Topical mometasone furoate for vulvar lichen sclerosus."
04/01/2015 - "To compare the efficacy of the short-term application of clobetasol propionate 0.05% (CLB) and mometasone furoate 0.05% (MMF) in the treatment of vulvar lichen sclerosus (VLS). "

07/01/1994 - "Comparison between 2% testosterone propionate and petrolatum ointment in the treatment of vulvar lichen sclerosus in a randomized, double-blind, controlled clinical study. "
01/01/1998 - "Clobetasol dipropionate 0.05% versus testosterone propionate 2% topical application for severe vulvar lichen sclerosus."
04/01/1996 - "To test this hypothesis, five women with vulvar lichen sclerosus received topically either dihydrotestosterone or testosterone propionate in a double-blind cross-over study. "
02/01/1992 - "Thumb nails with asymptomatic red lunulae were noted in a 54-year-old woman with testosterone propionate-responsive vulvar lichen sclerosus et atrophicus of 4 years' duration and localized vitiligo that had been treated with topical corticosteroids for 15 months. "
01/01/1991 - "A case is reported of severe hirsutism with other signs of virilization and markedly elevated serum testosterone levels secondary to use of topical testosterone propionate for vulvar lichen sclerosus et atrophicus. "

09/01/2009 - "Topical tacrolimus for recalcitrant vulvar lichen sclerosus."
02/01/2007 - "This is the first report of topical low-concentration tacrolimus treatment showing a dramatic effect in the treatment of childhood vulvar lichen sclerosus."
02/01/2007 - "Successful treatment of vulvar lichen sclerosus in a child with low-concentration topical tacrolimus ointment."
01/01/2007 - "Vulvar lichen sclerosus: 11 women treated with tacrolimus 0.1% ointment."
11/01/2005 - "Vulvar lichen sclerosus successfully treated with topical tacrolimus."

07/01/1994 - "Petrolatum ointment is as effective as 2% testosterone in the treatment of vulvar lichen sclerosus."
07/01/1994 - "Comparison between 2% testosterone propionate and petrolatum ointment in the treatment of vulvar lichen sclerosus in a randomized, double-blind, controlled clinical study. "
01/01/2000 - "Our data do not confirm an autoimmune pathogenesis for vulvar lichen sclerosus but help explain why systemic cortisone is of no benefit and justify the use of petroleum jelly to relieve pruritus."
01/01/1998 - "Our goal was to evaluate short-term (3 months) and long-term (1 year) treatment of vulvar lichen sclerosus, by comparing topical application of testosterone propionate 2% in petrolatum with the corticosteroid clobetasol dipropionate 0.05%. "

04/01/1996 - "Impairment of 5-alpha reductase may not be germane to the pathogenesis of vulvar lichen sclerosus."
04/01/1996 - "Testosterone propionate has been shown repeatedly to be effective in the treatment of vulvar lichen sclerosus, yet studies of androgens in serum of women with untreated vulvar lichen sclerosus suggested an abnormal activity of 5-alpha reductase in these patients. "
04/01/1996 - "If impairment of 5-alpha reductase in women with untreated vulvar lichen sclerosus is a proximate cause of this disease, then dihydrotestosterone should be more effective than testosterone propionate in the treatment of the condition. "

12/01/2008 - "An open trial of 5-aminolevulinic acid photodynamic therapy for vulvar lichen sclerosus."
01/01/2015 - "The authors report the case of a 75-year-old woman with highly symptomatic vulvar lichen sclerosus, successfully treated with photodynamic therapy. "
06/01/2012 - "Photodynamic therapy of vulvar lichen sclerosus et atrophicus in a woman with hypothyreosis--case report."
12/01/2009 - "Sexual functions and depressive symptoms after photodynamic therapy for vulvar lichen sclerosus in postmenopausal women from the Upper Silesian Region of Poland."
08/01/2007 - "Treatment of recalcitrant erosive vulvar lichen sclerosus with photodynamic therapy."

11/01/1984 - "[Electrophysiological studies of the nervous system in patients with kraurosis vulvae after laser therapy]."
10/01/1991 - "Laser therapy of vulvar lichen sclerosus et atrophicus."

01/01/1972 - "[Comparative study of treatment of kraurosis vulvae (lichen scleroatrophicus vulvae) with ultrasound, hydrocortisone ointment and phonophoresis with hydrocortisone ointment]."
01/01/1971 - "[Histological changes in external genital organs in patients with kraurosis vulvae, treated by phonophoresis and hydrocortisone ointment]."

09/01/2015 - "Herein, strategies for diagnosing vulvar lichen sclerosus, lichen planus, contact dermatitis, lichen simplex chronicus, and psoriasis are discussed along with basic management of these diseases, which commonly involves decreasing inflammation through behavioral change, gentle skin care, topical corticosteroids, and systemic therapies. "

01/01/2015 - "Conscious sedation with inhaled 50% nitrous oxide/oxygen premix in photodynamic therapy sessions for vulvar lichen sclerosus treatment."