Kaolin

The most common mineral of a group of hydrated aluminum silicates, approximately H2Al2Si2O8-H2O. It is prepared for pharmaceutical and medicinal purposes by levigating with water to remove sand, etc. (From Merck Index, 11th ed) The name is derived from Kao-ling (Chinese: "high ridge"), the original site. (From Grant & Hackh's Chemical Dictionary, 5th ed)

Also Known As:

Networked: 734 relevant articles (9 outcomes, 86 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Del Bigio, Marc R: 16 articles (01/2014 - 01/2002)
2.	Neugebauer, Volker: 14 articles (01/2015 - 02/2003)
3.	Yuan, Chun-Su: 9 articles (01/2009 - 12/2003)
4.	Yamamoto, Kouichi: 8 articles (10/2015 - 06/2002)
5.	Yamatodani, Atsushi: 8 articles (10/2015 - 06/2002)
6.	Ji, Guangchen: 8 articles (01/2015 - 01/2007)
7.	McAllister, James P: 7 articles (10/2014 - 06/2008)
8.	Sluka, Kathleen A: 7 articles (01/2010 - 09/2003)
9.	Wang, Chong-Zhi: 7 articles (01/2009 - 01/2004)
10.	Xie, Jing-Tian: 7 articles (11/2007 - 12/2003)

Related Diseases

1.	Hyperalgesia 04/01/2008 - "The combination of SCI and subarachnoid kaolin injection resulted in a significantly greater syrinx formation and perilesional myelomalacia than SCI alone; SCI and kaolin injection significantly attenuated locomotor recovery and exacerbated neuropathic pain (mechanical allodynia) compared with SCI alone. " 07/19/2007 - "Modifications in temperature, body weight gain, food and kaolin intake, and the threshold for mechanical allodynia were recorded. " 05/01/1998 - "The present study investigated whether spinal administration of S-(+)-3-isobutylgaba (S-(+)-3-IBG) or its stereoisomer, R-(-)-3-isobutylgaba (R-(-)-3-IBG), are effective in reducing the hyperalgesia and swelling observed after injection of kaolin and carrageenan into the knee joint of the rat. " 01/01/2008 - "The spinal GLT-1 gene transfer had no effect on acute mechanical and thermal nociceptive responses in naive rats, whereas it significantly reduced the inflammatory mechanical hyperalgesia induced by hindlimb intraplantar injection of carrageenan/kaolin. " 10/01/2005 - "Hyperalgesia was induced in rats by inflaming one knee joint with 3% kaolin-carrageenan and assessed by measuring paw withdrawal latency to heat before and 4 hours after injection. "
2.	Birth Weight (Birth Weights) 11/01/1977 - "There was also a significant reduction in the birth weight of the pups born to kaolin fed rats. " 01/01/2003 - "Female rats receiving a 20% Kaolin diet exhibited maternal anemia but no significant reduction in birth weight of the pups was recorded. "
3.	Hydrocephalus (Hydrocephaly) 01/01/2015 - "In this study, we attempted to construct a high-efficiency model of hydrocephalus via intraventricular kaolin injection. " 06/01/2013 - "In this study, we attempted to investigate the role and expression of HGF, MMP-9 and TGF-β1 in the cerebral tissue and cerebrospinal fluid (CSF) of adult rats with hydrocephalus induced via intraventricular kaolin injection. " 01/01/2013 - "The objective of this study was to examine host-shunt interactions in sheep with kaolin-induced hydrocephalus. " 04/01/2011 - "The present study was designed to investigate anxiety responses in rats with kaolin-induced hydrocephalus. " 05/01/2008 - "Because a significant portion of CSF absorption occurs into extracranial lymphatics located in the olfactory turbinates, the purpose of this study was to determine whether CSF transport was compromised at this location in a kaolin-induced communicating (extraventricular) hydrocephalus model in rats. "
4.	Inflammation 08/01/2011 - "The paw inflammation developed within a few hours, reached maximum values 24 h and up to 3 days after kaolin administration, and then progressively resolved over 2 months. " 08/01/2011 - "A kaolin-induce paw inflammation model previously developed in cats was adapted to the dog. " 09/01/2007 - "In histopathologic changes, exposure to ASDP prominently enhanced pulmonary neutrophilic inflammation, followed by kaolin and ASDP-F exposure in the order. " 08/01/2007 - "In part 2, the process was repeated after intradermal kaolin induced mild inflammation at the test site. " 03/03/2005 - "When comparing two types of model inflammations (kaolin- and Staphylococcus-induced ones), the values measured with 99mTc-peptides are more than double than those of kaolin suspension inflammation. "
5.	Hemorrhage 05/01/2014 - "Results of a kaolin-activated thromboelastography assay, platelet count, and buccal mucosal bleeding time were evaluated for correlation to clinical bleeding. " 11/01/2011 - "Histopathological lesions were observed in the esophagus, proventriculus, ventriculus, and duodenum of SAMW-treated mallards, with the most distinctive being erosion and ulceration of the kaolin of the ventriculus, ventricular hemorrhage and/or congestion, and duodenal hemorrhage. " 02/01/2011 - "Randomized clinical trial on short-time compression with Kaolin-filled pad: a new strategy to avoid early bleeding and subacute radial artery occlusion after percutaneous coronary intervention." 09/01/2010 - "It was shown that the addition of kaolin delayed the initial setting time of CLSM mixtures, reduced bleeding, lowered the compressive strength, and increased the values of water absorption, sorption, and initial surface absorption. " 08/01/2006 - "In conclusion, the kaolin-activated TEG is associated with early coagulopathic bleeding. "

Related Drugs and Biologics

1.	Carrageenan
2.	Dextrans (Dextran)
3.	Antibodies
4.	Factor VIII (Coagulation Factor VIII)
5.	Prothrombin (Factor II)
6.	Acetone
7.	Nitric Oxide (Nitrogen Monoxide)
8.	Silicon Dioxide (Sand)
9.	Bentonite (Montmorillonite)
10.	attapulgite (palygorskite)

Related Therapies and Procedures

1.	Catheters
2.	Injections
3.	Transcutaneous Electric Nerve Stimulation (TENS)
4.	Laminectomy
5.	Therapeutics