Jejunoileal Bypass

A procedure consisting of the SURGICAL ANASTOMOSIS of the proximal part of the JEJUNUM to the distal portion of the ILEUM, so as to bypass the nutrient-absorptive segment of the SMALL INTESTINE. Due to the severe malnutrition and life-threatening metabolic complications, this method is no longer used to treat MORBID OBESITY.

Also Known As:

Jejuno-Ileal Bypass; Bypass, Ileojejunal; Bypass, Intestinal; Bypass, Jejuno-Ileal; Bypass, Jejunoileal; Bypasses, Ileojejunal; Bypasses, Intestinal; Bypasses, Jejuno-Ileal; Bypasses, Jejunoileal; Ileojejunal Bypasses; Intestinal Bypasses; Jejuno Ileal Bypass; Jejuno-Ileal Bypasses; Jejunoileal Bypasses; Ileojejunal Bypass; Intestinal Bypass

Networked: 952 relevant articles (35 outcomes, 46 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Rubino, Francesco: 4 articles (01/2021 - 11/2006)
2.	Ikramuddin, Sayeed: 4 articles (07/2016 - 07/2005)
3.	Ahn, Soo Min: 3 articles (04/2021 - 10/2011)
4.	Cao, Jiaqing: 3 articles (01/2021 - 01/2017)
5.	Duan, Jinyuan: 3 articles (01/2021 - 01/2017)
6.	Buchwald, Henry: 3 articles (12/2013 - 10/2002)
7.	Coe, Fredric L: 3 articles (03/2008 - 11/2005)
8.	Evan, Andrew P: 3 articles (03/2008 - 11/2005)
9.	Badiali, M: 3 articles (12/2004 - 08/2001)
10.	Hyung, Woo Jin: 2 articles (04/2021 - 11/2017)

Related Diseases

1.	Weight Loss (Weight Reduction) 06/01/2011 - "Bilio-intestinal bypass is effective in inducing weight loss and metabolic improvement. " 10/01/2016 - "Whilst currently an investigative procedure, and within the studies limitations combined sleeve gastrectomy with modified jejuno-ileal bypass is safe and effective, and evades many problems associated with current bariatric operations whilst offering maintained excess weight loss." 03/01/1988 - "This operation gives improved weight loss when compared with gastroplasty or gastric bypass alone and has none of the late complications associated with intestinal bypass." 07/01/1976 - "Weight reduction as a result of jejunoileal bypass surgery brings about an improvement in pulmonary function." 12/01/1979 - "The present studies were designed to compare physiological and behavioral changes produced by weight loss induced with dieting and the weight loss which follows intestinal bypass. "
2.	Morbid Obesity 12/01/1979 - "Jejunoileal bypass for morbid obesity with our current bowel length dimensional considerations has achieved good results in 74 per cent of patients. " 06/01/2004 - "Bariatric operations are currently the only effective treatment for morbid obesity The first operation, jejunoileal bypass (JIB), has been superceded. " 07/01/1986 - "Although jejunoileal bypass surgery proved effective in controlling morbid obesity, the serious adverse effects from the operation were ultimately found to outweigh the benefits. " 09/01/1984 - "Gastric partitioning is a safe and effective alternative to jejunoileal bypass in the control of morbid obesity. " 01/01/1981 - ""There is a consensus that jejunoileal bypass is no longer an acceptable operation for the treatment of morbid obesity because of well-documented serious complications." Over the past 3 years, experience with the gastric stapling procedure has shown it to be a safe and effective operation for the surgical treatment of morbid obesity. "
3.	Obesity 01/01/2012 - "Bariatric surgery is effective for treating serious obesity, and techniques involving intestinal bypass have metabolic benefits, such as complete and early remission of T2DM. " 10/01/2001 - "Bilio-intestinal bypass (BIB) is effective for the treatment of refractory obesity. " 01/01/1977 - "Improvement in quality of life following jejunoileal bypass surgery for obesity." 01/01/1986 - "With the aid of the national Medical Birth Registries and Discharge Registries in Denmark and Sweden it was possible to identify and study delivery outcome in 77 women who, prior to pregnancy, had undergone an intestinal bypass operation for obesity. " 01/01/1980 - "Jejunoileal bypass for obesity--what can we learn from a literature study?"
4.	Type 2 Diabetes Mellitus (MODY) 11/17/2022 - "In most cases, metabolic procedures, especially those that include intestinal bypass components, showed the remission of type 2 diabetes. " 01/01/2011 - "Metabolic intestinal bypass surgery for type 2 diabetes in low BMI patients is effective, with HbA1c levels at 1 year after the operation being significantly lower after BPD-DS or BPD than after RYGB." 10/01/2011 - "Bariatric procedures differ in their ability to ameliorate type 2 diabetes, with intestinal bypass procedures being more effective than purely restrictive procedures. " 01/01/2011 - "Rapid resolution of type 2 diabetes mellitus (T2DM) is a common feature after intestinal bypass surgery bypassing the duodenum and parts of the jejunum. " 01/01/2011 - "Metabolic intestinal bypass surgery was performed in n = 16 patients with type 2 diabetes and a BMI < 35 kg/m(2) (mean age 56 years, range 36-68; 8 females; mean BMI 32 kg /m(2), range 26-34.5). "
5.	Liver Failure 10/01/2017 - "An extensive literature search of MEDLINE was performed using different combinations of the following terms: "bariatric surgery OR biliopancreatic diversion OR jejunoileal bypass OR roux-en-y gastric bypass OR vertical banded gastroplasty OR laparoscopic adjustable gastric banding" AND "hepatic/liver damage OR hepatic/liver impairment OR hepatic/liver failure". " 01/01/2017 - "Occurrences of liver failure following jejunoileal bypass were extensively reported in the past and were one of the main factors that led to abandonment of this procedure. " 04/16/2013 - "Liver failure has been reported after jejunoileal bypass (JIB), biliopancreatic diversion and gastric bypass. " 12/01/2010 - "Fatal liver failure (LF) has been recorded after jejunoileal bypass (JIB) but is controversial after biliopancreatic diversion (BPD, Scopinaro operation). " 09/01/2006 - "One of the reasons why jejunoileal bypass (JIB) was abandoned were reports of liver failure. "

Related Drugs and Biologics

1.	Glucose (Dextrose)
2.	Calcium Oxalate
3.	Anti-Bacterial Agents (Antibiotics)
4.	Gastrointestinal Hormones (Hormones, Gastrointestinal)
5.	Adipokines
6.	Bile Acids and Salts (Bile Acids)
7.	Electrolytes
8.	Peptides (Polypeptides)
9.	Calcium-Binding Proteins
10.	Appetite Depressants (Anorectics)

Related Therapies and Procedures

1.	Gastrectomy
2.	Gastric Bypass (Roux-en-Y Gastric Bypass)
3.	Bariatric Surgery
4.	Gastroplasty (Vertical-Banded Gastroplasty)
5.	Therapeutics