Inosine Pranobex (Imunovir)

An alkylamino-alcohol complex of inosine used in the treatment of a variety of viral infections. Unlike other antiviral agents, it acts by modifying or stimulating cell-mediated immune processes rather than acting on the virus directly.

Also Known As:

Networked: 294 relevant articles (39 outcomes, 56 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Hosoya, Mitsuaki: 3 articles (04/2012 - 08/2007)
2.	Lasek, Witold: 2 articles (06/2015 - 01/2015)
3.	Aydin, Omer Faruk: 2 articles (11/2004 - 02/2003)
4.	Bai, Li: 1 article (06/2015)
5.	Janyst, Michał: 1 article (06/2015)
6.	Wang, Li: 1 article (06/2015)
7.	Cao, Shuanglin: 1 article (06/2015)
8.	Li, Yafei: 1 article (06/2015)
9.	Zapała, Łukasz: 1 article (06/2015)
10.	Wei, Zhiping: 1 article (06/2015)

Related Diseases

1.	Subacute Sclerosing Panencephalitis (SSPE) 03/01/1981 - "The presented data are insufficient for a reliable conclusion to be drawn concerning the effect of various drugs on the course of SSPE, nevertheless, it seems that the best results with slowing down of the progression of the disease were observed in the group treated with isoprinosine." 08/01/1982 - "These findings suggest that inosiplex is effective in the slowly developing or chronic form of SSPE." 04/01/1983 - "Progressive CT abnormalities despite clinical improvement in SSPE treated with inosiplex." 02/01/2006 - "Inosiplex is one of the effective drugs for subacute sclerosing panencephalitis, but our in vivo and in vitro magnetic resonance spectroscopic study indicated that inosiplex affects the spectra, suggesting a possible failure of neurologic evaluation in a patient with subacute sclerosing panencephalitis treated with inosiplex." 01/01/1994 - "The effect of inosiplex in subacute sclerosing panencephalitis: a clinical and laboratory study."
2.	Infection 08/01/1981 - "[Protective effects of inosiplex in viral infections. " 08/01/1981 - "[Protective effects of inosiplex in viral infections. " 06/01/1992 - "One-year follow-up on the safety and efficacy of isoprinosine for human immunodeficiency virus infection. " 01/01/1987 - "Our results motivate a clinical study with isoprinosine in uremic patients at the risk of virus infection." 01/01/1981 - "[Clinical study of the use of isoprinosine in viral infections]."
3.	Acquired Immunodeficiency Syndrome (AIDS) 05/30/1994 - "We conclude that HIV-infected individuals without AIDS may be safely and effectively treated with isoprinosine." 06/01/1992 - "We conclude that HIV-seropositive patients without AIDS may be safely and effectively treated with isoprinosine." 10/01/1988 - "Many synthetic compounds possess immunomodulatory properties; one of these, inosiplex, may prove effective in enhancing immune function in patients with immune deficiencies such as AIDS." 06/27/1990 - "[Promising results of a Danish-Swedish clinical trial: isoprinosine administered to HIV positive patients prevented development of AIDS]." 02/01/1992 - "During the study, AIDS developed in 19 patients; 17 of whom were receiving placebo treatment and two isoprinosine. "
4.	Herpes Genitalis (Genital Herpes) 10/01/1992 - "Acyclovir is very effective in suppressing recurrent genital herpes and is clearly superior to isoprinosine which is not clinically useful in the dosage studied." 06/01/2015 - "In conclusion, inosine pranobex was as effective as acyclovir in treating RHL and RHG with significantly greater reduction of the short-term recurrence rate of herpes genitalis at 3-month follow up. " 05/23/1987 - "77 patients with a first attack of genital herpes were entered into a double-blind trial to compare the efficacy of acyclovir with that of inosine pranobex. " 04/01/1989 - "The suppressive action of acyclovir and inosine pranobex was compared in a randomised double blind controlled trial in patients with frequently recurring genital herpes. " 08/29/1988 - "Preliminary results from two trials suggest that suppressive acyclovir is more efficacious than inosine pranobex in patients with frequently recurring genital herpes."
5.	Condylomata Acuminata (Genital Wart) 10/01/1986 - "Inosine pranobex was found to be more effective in lesions of longer duration, whereas conventional treatment was more effective in genital warts of a shorter duration. " 03/01/2015 - "This study evaluates the effectiveness of immunomodulating drug isoprinosine in a comprehensive treatment of genital warts in men. " 04/01/2007 - "Re: oral inosiplex in the treatment of cervical condylomata acuminata: a randomised placebo-controlled trial." 09/01/2006 - "Oral inosiplex in the treatment of cervical condylomata acuminata: a randomised placebo-controlled trial." 09/01/2006 - "Inosiplex may represent an efficacious and safe alternative systemic form of therapy for cervical genital warts."

Related Drugs and Biologics

1.	Acyclovir (Aciclovir)
2.	Interferons
3.	Levamisole (Decaris)
4.	Inosine Pranobex (Imunovir)
5.	Interferon-alpha (Interferon Alfa)
6.	Antigens
7.	Immunologic Factors (Immunomodulators)
8.	TFX
9.	Podophyllin
10.	Fluorouracil (Carac)

Related Therapies and Procedures

1.	Radiotherapy
2.	Investigational Therapies (Experimental Therapy)
3.	Immunotherapy
4.	Immunomodulation
5.	Transplants (Transplant)