Isoflavones

01/01/2007 - "With the current evidence on the cancer preventive properties of isoflavones, these results are significant and offer promise for these phytochemicals to be developed as potent agents to prevent cancer progression."
03/01/1995 - "Although still speculative, greater dietary incorporation of soybean products, because of the high concentration of isoflavones, may be a safe and effective means of reducing cancer risk."
12/01/2015 - "Isoflavones have been suggested to have protective effects on certain cancers. "
02/01/2004 - "Chemical induction of mammary tumors in female rats has been used to determine that exposure of the mammary gland to soy isoflavones prior to tumor induction is protective against tumor formation. "
07/01/2002 - "The potential cancer preventive efficacy of soy isoflavones is being investigated in preclinical and phase 1 clinical studies sponsored by the U.S. "

02/01/2012 - "A 6-month intervention of mixed soy isoflavones in healthy, high-risk adult Western women did not reduce breast epithelial proliferation, suggesting a lack of efficacy for breast cancer prevention and a possible adverse effect in premenopausal women."
01/01/2013 - "Soy intake consistent with that of a traditional Japanese diet (2-3 servings daily, containing 25-50mg isoflavones) may be protective against breast cancer and recurrence. "
11/01/2012 - "Meta-analyses of epidemiological studies of soy consumption and breast cancer risk have demonstrated modest protective effects, usually attributed to isoflavones. "
01/01/2010 - "It has been suggested that soy isoflavones have protective effects against breast cancer. "
08/01/2008 - "Recent reports have indicated that soy isoflavones may be protective against breast cancer. "

01/01/2013 - "Significant advances have been made for understanding how soy isoflavones are implicated in protection against prostate cancer. "
01/01/2007 - "However, the modest individual activities of soy isoflavones and BBIC suggest that while both components may contribute to the chemopreventive activity of soy, combination administration (or exposure to whole soy) may be more effective in prostate cancer prevention than is administration of either component alone."
01/01/2010 - "The purpose of this phase I dose-finding randomized controlled trial was to evaluate the safe and effective dose of isoflavones to be used in future clinical trials for prostate cancer prevention. "
07/01/2006 - "The clinical evidence is sufficiently encouraging to justify considering additional Phase II and III clinical trials investigating the efficacy of soy isoflavones in different populations of prostate cancer patients alone and in combination with other treatments."
02/01/2003 - "Our studies suggest that use of the PART-1 gene as a biomarker for evaluating the efficacy of soy isoflavones on androgen-dependent prostate cancer warrants further investigation."

06/01/2009 - "We evaluated the protective effects of soy isoflavones (SIF) against osteoporosis in middle-aged ovariectomized (OVX) mice. "
04/01/2002 - "Because of this natural and synthetic isoflavones hold great promise in the prevention and treatment of osteoporosis. "
03/01/2012 - "Random control trials that investigated the association of soy isoflavones and osteoporosis were included in the meta-analysis by researching MEDLINE, EMBASE and the Chinese Biomedical Database up to October 2011. "
12/01/2011 - "Further studies are needed to address factors affecting the magnitude of the beneficial effects of soy isoflavones and to assess the possible interactions between soy isoflavones and anti-osteoporosis drugs, and to verify effects on BMD of other skeletal sites and other bone turnover markers."
10/01/2010 - "This study demonstrates that kudzu isoflavones and metabolites are capable of reaching bone tissues, where they may contribute to the prevention of osteoporosis and the promotion of bone health."

02/01/2008 - "Protective effects of soy-isoflavones in cardiovascular disease. "
09/01/2015 - "The results of this study indicated the potential biological relevance of soy isoflavones in the therapy of cardiovascular diseases."
04/01/2001 - "Intervention data suggest a cardioprotective role for supplemental isoflavones; however, few studies have examined the cardiovascular disease (CVD) benefit of usual dietary isoflavone intake. "
06/01/2013 - "Isoflavones have been associated with lower cardiovascular disease risk, but existing research focused on very high isoflavone intakes, as seen in Asian populations, as well as on risk factor reductions primarily in postmenopausal women. "
04/01/2012 - "Soy isoflavones and cardiovascular disease epidemiological, clinical and -omics perspectives."