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Iris Diseases

Subscribe to New Research on Iris Diseases

Diseases, dysfunctions, or disorders of or located in the iris.

Also Known As:

Disease, Iris; Diseases, Iris; Iris Disease

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Eye Diseases: 2132
- Uveal Diseases: 16
  - Iris Diseases: 3

Related Diseases

1.	Melanoma (Melanoma, Malignant)
2.	Glaucoma

Experts

1.	John, Simon W M: 2 articles (01/2008 - 01/2006)
2.	Anderson, Michael G: 2 articles (01/2008 - 01/2006)
3.	Chou, Tsung-Han: 1 article (01/2010)
4.	Porciatti, Vittorio: 1 article (01/2010)
5.	Feuer, William J: 1 article (01/2010)
6.	Masli, Sharmila: 1 article (01/2008)
7.	Amonoo, Leslie A: 1 article (01/2008)
8.	Mehalow, Adrienne: 1 article (01/2008)
9.	Trantow, Colleen M: 1 article (01/2008)
10.	Nair, K Saidas: 1 article (01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Iris Diseases:

1.	Monophenol Monooxygenase (Tyrosinase)IBA 01/01/2006 - "Genetic epistasis experiments introducing a B6 tyrosinase mutation into the congenic strains demonstrated that both the single and double-congenic iris diseases are rescued by interruption of melanin synthesis. " 01/01/2010 - "C57BL/6J (B6) and DBA/2J (D2) are the two most common mouse strains; D2 has two mutated genes, tyrosinase-related protein 1 (Tyrp1) and glycoprotein non-metastatic melanoma protein B (Gpnmb), causing iris disease and intraocular pressure (IOP) elevation after 6 months of age that results in RGC degeneration, and is the most widely used model of glaucoma. "
2.	Interleukin-18 (Interleukin 18)IBA 01/01/2008 - "Finally, we show that the Gpnmb mediated iris disease does not require elevated IL18 or mature B or T lymphocytes. "
3.	Melanins (Melanin)IBA 01/01/2006 - "Genetic epistasis experiments introducing a B6 tyrosinase mutation into the congenic strains demonstrated that both the single and double-congenic iris diseases are rescued by interruption of melanin synthesis. "
4.	Glycoproteins (Glycoprotein)IBA 01/01/2010 - "C57BL/6J (B6) and DBA/2J (D2) are the two most common mouse strains; D2 has two mutated genes, tyrosinase-related protein 1 (Tyrp1) and glycoprotein non-metastatic melanoma protein B (Gpnmb), causing iris disease and intraocular pressure (IOP) elevation after 6 months of age that results in RGC degeneration, and is the most widely used model of glaucoma. "
5.	IgA receptor (protein B)IBA 01/01/2010 - "C57BL/6J (B6) and DBA/2J (D2) are the two most common mouse strains; D2 has two mutated genes, tyrosinase-related protein 1 (Tyrp1) and glycoprotein non-metastatic melanoma protein B (Gpnmb), causing iris disease and intraocular pressure (IOP) elevation after 6 months of age that results in RGC degeneration, and is the most widely used model of glaucoma. "