Iproniazid

An irreversible inhibitor of monoamine oxidase types A and B that is used as an antidepressive agent. It has also been used as an antitubercular agent, but its use is limited by its toxicity.

Also Known As:

Iprazid; 4-Pyridinecarboxylic acid, 2-(1-methylethyl)hydrazide

Networked: 211 relevant articles (1 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrazines: 379
  - Iproniazid: 211
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Isonicotinic Acids: 144
      - Iproniazid: 211
- Heterocyclic Acids
  - Isonicotinic Acids: 144
    - Iproniazid: 211

Experts

1.	Dethloff, Frederik: 1 article (01/2020)
2.	Dorrestein, Pieter C: 1 article (01/2020)
3.	Elijah, Emmanuel: 1 article (01/2020)
4.	Gentry, Emily C: 1 article (01/2020)
5.	Gonzalez, Antonio: 1 article (01/2020)
6.	Herzog, David P: 1 article (01/2020)
7.	Knight, Rob: 1 article (01/2020)
8.	Müller, Marianne B: 1 article (01/2020)
9.	Park, Dong Ik: 1 article (01/2020)
10.	Quinn, Robert: 1 article (01/2020)

Related Diseases

1.	Osteoarticular Tuberculosis 10/01/1956 - "[Iproniazid for bone and joint tuberculosis]." 07/01/1953 - "The use of iproniazid in the treatment of bone and joint tuberculosis." 01/01/1955 - "A comparison of the efficacy of iproniazid (marsilid) and isoniazid (rimifon) in the treatment of bone and joint tuberculosis."
2.	Angina Pectoris 01/01/1962 - "Further trials with iproniazid in angina pectoris." 09/01/1961 - "[Clinical studies on the effect of iprazid in stenocardia. " 05/01/1968 - "[Experience with Iprazid treatment of patients with stenocardia]." 10/01/1963 - "[CLINICAL OBSERVATIONS ON THE USE OF IPRAZID IN STENOCARDIA PATIENTS]." 05/01/1963 - "[TREATMENT OF STENOCARDIA WITH IPRAZID]."
3.	Depressive Disorder (Melancholia) 07/01/1960 - "A controlled trial of iproniazid in the treatment of endogenous depression." 10/01/1963 - "[REMARKS ON THE ACTION OF IPRONIAZID (MARSILID) IN DEPRESSIVE SYNDROMES]." 03/12/1960 - "Iproniazid in the Treatment of Depressive Syndromes." 02/01/1960 - "[First results with a new iproniazid derivative, Ro 5-0831 (marplan), in depressive syndromes]." 06/13/1959 - "Effects of iproniazid in depressive syndromes."
4.	Psychotic Disorders (Schizoaffective Disorder) 12/11/1958 - "[Trials with iproniazid in psychoses]." 07/01/1960 - "[Clinical experiences with iproniazid ("Marsilid") in psychoses)]." 08/01/1953 - "[Iproniazid in neuroses and psychoses preceded by bacillar diseases]." 05/01/2001 - "Two mechanisms of action for isoniazid-related psychosis are kept by the majority of authors: pyridoxin deficiency isoniazid toxicity, molecule near chemically to iproniazid, powerful IMAO (monoamine oxydase inhibitor). "
5.	Rheumatoid Arthritis 01/01/1959 - "A preliminary study of iproniazid in rheumatoid arthritis." 04/01/1957 - "The effect of isoniazid and of iproniazid in patients with rheumatoid arthritis." 09/17/1959 - "The effects of iproniazid and other amine oxidase inhibitors in rheumatoid arthritis." 03/01/1958 - "[The effects of marsilid (iproniazid) in patients of rheumatoid arthritis and the theoretical causal role of certain amine oxidases]."

Related Drugs and Biologics

1.	Isoniazid (Ftivazide)
2.	Reserpine (Serpasil)
3.	Phosphates (Orthophosphate)
4.	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)
5.	Antidepressive Agents (Antidepressants)
6.	Serotonin (5 Hydroxytryptamine)
7.	5-Hydroxytryptophan (5 Hydroxytryptophan)
8.	Tetrabenazine (Nitoman)
9.	Streptomycin (Streptomycin Sulfate)
10.	Norepinephrine (Noradrenaline)

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Liver Transplantation