Iprindole

A tricyclic antidepressant that has actions and uses similar to those of AMITRIPTYLINE, but has only weak antimuscarinic and sedative effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p257)

Also Known As:

Networked: 34 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

1.	Cardiac Arrhythmias (Arrythmia) 07/15/1986 - "The present data indicate that iprindole may exert beneficial therapeutic effects in the treatment of cardiac arrhythmias, mediated, at least in part, through a Class I mechanism of action." 07/15/1986 - "The antiarrhythmic activity of iprindole was compared to that of imipramine in a variety of experimental arrhythmia models. "
2.	Lipidoses 08/20/1976 - "This study deals with the effects of two amphiphilic lipidosis-inducing drugs (chlorphentermine, iprindole) upon the ultrastructure of peripheral nerves of rats. " 06/24/1974 - "Lipidosis-like alterations in hypothalamic neurosecretory cells of rats treated with chlorphentermine or iprindole." 03/01/1974 - "Proceedings: Lipidosis-like ultrastructural alterations in rat tissues induced by an antidepressant drug (iprindole)." 01/01/1983 - "After chronic oral treatment with chlorphentermine, iprindole, or tamoxifen all animals showed clear lipidosis-like alterations in corneal cells. " 06/01/1977 - "Lens opacities associated with lipidosis-like ultrastructural alterations in rats treated with chloroquine, chlorphentermine, or iprindole."
3.	Interstitial Lung Diseases (Interstitial Lung Disease) 01/01/1973 - "Pulmonary alveolar proteinosis developing from desquamative interstitial pneumonia in long term toxicity studies of iprindole in the rat." 10/01/1972 - "Pulmonary histiocytosis simulating desquamative interstitial pneumonia in rats receiving oral iprindole."
4.	Depressive Disorder (Melancholia) 01/01/1982 - "The plasma levels of iprindole were determined in five healthy volunteers following the administration of a single oral dose of 60 mg and in four patients admitted for endogenous depression after a 3-week administration of 90 mg d-1. " 02/01/1985 - "Rapid response to the addition of lithium in iprindole-resistant unipolar depression: a pilot study." 02/01/1985 - "The authors administered lithium carbonate, 900 mg/day, in an open study to seven patients with a major unipolar depression refractory to 3-week treatment with iprindole, 90 mg/day, a tricyclic antidepressant devoid of any action on monoaminergic reuptake. "
5.	Pulmonary Alveolar Proteinosis 01/01/1973 - "Pulmonary alveolar proteinosis developing from desquamative interstitial pneumonia in long term toxicity studies of iprindole in the rat."

Related Drugs and Biologics

1.	Chlorphentermine (Chlorphentermine Hydrochloride)
2.	Antidepressive Agents (Antidepressants)
3.	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)
4.	Lithium Carbonate (Eskalith)
5.	Appetite Depressants (Anorectics)
6.	Amitriptyline (Elavil)
7.	Imipramine (Janimine)
8.	Desipramine (Pertofrane)
9.	Clomipramine (Anafranil)
10.	Fluvoxamine (Luvox)