Ipecac (Syrup of Ipecac)

A syrup made from the dried rhizomes of two different species, CEPHAELIS ipecacuanha and C. acuminata. They contain EMETINE, cephaeline, psychotrine and other ISOQUINOLINES. Ipecac syrup is used widely as an emetic acting both locally on the gastric mucosa and centrally on the chemoreceptor trigger zone.

Also Known As:

Networked: 194 relevant articles (15 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Fathi, Hamed: 2 articles (03/2019 - 10/2015)
2.	Mohammadi, Hamidreza: 2 articles (03/2019 - 10/2015)
3.	Ziar, Ali: 2 articles (03/2019 - 10/2015)
4.	Birmingham, C L: 2 articles (03/2007 - 03/2004)
5.	Cobaugh, Daniel J: 2 articles (01/2006 - 01/2005)
6.	Manoguerra, Anthony S: 2 articles (01/2006 - 01/2005)
7.	Bleasel, Martin D: 1 article (03/2020)
8.	Peterson, Gregory M: 1 article (03/2020)
9.	Ebrahimzadeh, Mohammad Ali: 1 article (03/2019)
10.	Avau, Bert: 1 article (12/2018)

Related Diseases

1.	Vomiting 04/01/1986 - "The failure rate and the time for emesis to occur is significantly greater when 15 ml is used compared to 30 ml. To reduce failure rates, efforts such as consuming the entire contents of a 15 ml or 30 ml bottle of syrup of ipecac or using kitchen measuring spoons are frequently employed. " 05/01/1989 - "The knee-chest position does not improve the efficacy of ipecac-induced emesis." 09/01/1988 - "Efficacy of syrup of ipecac-induced emesis for emptying gastric contents." 06/01/1986 - "Efficacy of gastric emptying: gastric lavage versus emesis induced with ipecac." 01/01/2005 - "Studies to determine the effectiveness of ipecac syrup demonstrate that it induces vomiting in a high percentage of people to whom it is administered and that it decreases the gastrointestinal absorption of ingested substances in a time-dependent fashion. "
2.	Drug Overdose 06/01/1986 - "A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. " 12/01/1984 - "Six hours earlier she had received syrup of ipecac to induce emesis following a drug overdose. " 10/01/1989 - "The emetic agent ipecac is widely used for the initial treatment of acute oral drug overdose. " 08/01/1987 - "The efficacy of ipecac-induced emesis, large-bore orogastric lavage, and activated charcoal as gastrointestinal decontamination procedures after acute drug overdose is unknown. " 08/01/1987 - "Efficacy of ipecac-induced emesis, orogastric lavage, and activated charcoal for acute drug overdose."
3.	Nausea 07/01/2001 - "Nausea and emesis were induced by syrup of ipecac. " 07/01/2001 - "Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac." 02/01/1949 - "Studies on nausea; effects of ipecac and other emetics on the human stomach and duodenum." 09/01/1976 - "In normal human subjects, a bismuth subsalicylate suspension, unlike the placebo formulation, successfully subdued nausea and vomiting in 66.7 and 80% of the subjects, respectively, in response to ipecac syrup. "
4.	Toothache (Toothaches) 11/01/1892 - "Odontalgia Cured by Ipecac."
5.	Poisoning 12/19/2018 - " one study compared SDAC to syrup of ipecac in participants with mixed types of poisoning, providing very low-certainty evidence. " 12/01/2017 - "50 Years Ago in The Journal of Pediatrics: Public Knowledge of Ipecac Syrup in the Management of Accidental Poisonings." 11/01/2003 - "The usefulness of syrup of ipecac as a home treatment for poisoning and the need to keep it in the home has been increasingly challenged. " 01/01/2003 - "The home administration of ipecac syrup remains a recommendation in some guidelines for the management of specific pediatric poisonings. " 10/01/2001 - "Toxic topic: ipecac for the treatment of pediatric poisonings."

Related Drugs and Biologics

1.	Emetics
2.	Charcoal (Charbon)
3.	Antiemetics
4.	Apomorphine
5.	Poisons
6.	Cisplatin (Platino)
7.	Ondansetron (Zofran)
8.	Metoclopramide (Reglan)
9.	Chlorpromazine (Thorazine)
10.	maropitant

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Therapeutics
3.	First Aid (Aids, First)
4.	Secondary Prevention
5.	Enema (Enemas)