Ipecac (Syrup of Ipecac)

A syrup made from the dried rhizomes of two different species, CEPHAELIS ipecacuanha and C. acuminata. They contain EMETINE, cephaeline, psychotrine and other ISOQUINOLINES. Ipecac syrup is used widely as an emetic acting both locally on the gastric mucosa and centrally on the chemoreceptor trigger zone.

Also Known As:

Networked: 176 relevant articles (14 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Birmingham, C L: 2 articles (03/2007 - 03/2004)
2.	Cobaugh, Daniel J: 2 articles (01/2006 - 01/2005)
3.	Manoguerra, Anthony S: 2 articles (01/2006 - 01/2005)
4.	Bond, Alexander L: 1 article (05/2013)
5.	Lavers, Jennifer L: 1 article (05/2013)
6.	Forrester, Mathias B: 1 article (11/2009)
7.	Kupferschmidt, Hugo: 1 article (05/2009)
8.	Züst, Ariane: 1 article (05/2009)
9.	Rauber-Lüthy, Christine: 1 article (05/2009)
10.	Eagleson, J S: 1 article (12/2008)

Related Diseases

1.	Vomiting 04/01/1986 - "The failure rate and the time for emesis to occur is significantly greater when 15 ml is used compared to 30 ml. To reduce failure rates, efforts such as consuming the entire contents of a 15 ml or 30 ml bottle of syrup of ipecac or using kitchen measuring spoons are frequently employed. " 05/15/2013 - "We used Leach's Storm-petrels (Oceanodroma leucorhoa) in Newfoundland to study the effect of dose volume, and the efficacy of emesis using syrup of ipecac as an emetic. " 11/01/1985 - "The efficacy of ipecac syrup in the induction of emesis and safety of its administration was studied in 105 poison-exposed infants 6 through 11 months of age (study subjects) and compared prospectively with 302 poison-exposed infants and children 12 through 35 months of age who served as age controls. " 09/01/1993 - "To compare the efficacy of gastric lavage and ipecac-induced emesis by using a radionuclide marker in a simulated overdose and to determine the amount of material recoverable after lavage fluid appears clear. " 05/01/1989 - "The knee-chest position does not improve the efficacy of ipecac-induced emesis."
2.	Nausea 07/01/2001 - "Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac." 07/01/2001 - "Nausea and emesis were induced by syrup of ipecac. " 02/01/1949 - "Studies on nausea; effects of ipecac and other emetics on the human stomach and duodenum." 09/01/1976 - "In normal human subjects, a bismuth subsalicylate suspension, unlike the placebo formulation, successfully subdued nausea and vomiting in 66.7 and 80% of the subjects, respectively, in response to ipecac syrup. "
3.	Neoplasms (Cancer) 03/01/1994 - "Our study demonstrates that zatosetron has similar efficacy on ipecac-induced emesis in healthy men, as has been shown previously with other 5-HT3 receptor antagonists in chemotherapy-induced emesis in cancer patients. "
4.	Poisoning 09/01/2006 - "Report of one case of a child who was determined to be a victim of Munchausen syndrome by proxy by ipecac poisoning who was hospitalized multiple times over a 4-year period at 2 different hospitals before an accurate diagnosis was made." 09/01/2006 - "To present a case of Munchausen syndrome by proxy caused by ipecac poisoning to increase the awareness of their warning signs and symptoms so that they may be recognized and diagnosed earlier. " 09/01/2006 - "Munchausen syndrome by proxy caused by ipecac poisoning." 11/01/2003 - "The usefulness of syrup of ipecac as a home treatment for poisoning and the need to keep it in the home has been increasingly challenged. " 01/01/2003 - "The home administration of ipecac syrup remains a recommendation in some guidelines for the management of specific pediatric poisonings. "
5.	Muscular Diseases (Myopathy) 03/01/2006 - "Medically unexplained myopathy due to ipecac abuse." 05/01/1993 - "The myopathy resolved and the echocardiogram returned to normal after discontinuing the use of ipecac." 05/01/1993 - "Clinical and electromyographic data suggested ipecac myopathy and muscle biopsies confirmed this diagnosis. " 03/01/1992 - "Medical complications such as myopathy and gastrointestinal and other toxic effects can occur with ipecac abuse, the gravity of which must not be underestimated. " 01/01/1988 - "As the myopathy is clinically reversible upon discontinuation of ipecac consumption the morphological findings should also be potentially reversible. "

Related Drugs and Biologics

1.	Charcoal (Charbon)
2.	Apomorphine
3.	Cisplatin (Platino)
4.	Ondansetron (Zofran)
5.	Metoclopramide (Reglan)
6.	Chlorpromazine (Thorazine)
7.	maropitant
8.	Acetaminophen (Paracetamol)
9.	bemesetron
10.	5-HT3 Serotonin Receptors (5 HT3 Receptor)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	First Aid (Aids, First)
3.	Enema (Enemas)
4.	Aftercare (After-Treatment)