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Intestinal Neoplasms (Intestinal Cancer)

Subscribe to New Research on Intestinal Neoplasms

Tumors or cancer of the INTESTINES.

Also Known As:

Intestinal Cancer; Cancer of the Intestines; Intestines Cancer; Intestines Neoplasms; Neoplasms, Intestinal; Cancer, Intestinal; Cancer, Intestines; Cancers, Intestinal; Cancers, Intestines; Intestinal Cancers; Intestinal Neoplasm; Intestines Cancers; Intestines Neoplasm; Neoplasm, Intestinal; Neoplasm, Intestines; Neoplasms, Intestines; Cancer of Intestines

Networked: 314 relevant articles (14 outcomes, 34 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasm Metastasis (Metastasis)
2.	Neoplasms (Cancer)
3.	Breast Neoplasms (Breast Cancer)
4.	Colonic Neoplasms (Colon Cancer)
5.	Polyps

Experts

1.	Yang, Chung S: 3 articles (10/2012 - 11/2005)
2.	Ju, Jihyeung: 3 articles (10/2012 - 11/2005)
3.	Stover, Patrick J: 3 articles (03/2011 - 12/2009)
4.	McEntee, Michael F: 3 articles (03/2011 - 01/2002)
5.	Goodlad, Robert A: 3 articles (10/2010 - 03/2008)
6.	Proctor, Deborah M: 2 articles (08/2015 - 05/2014)
7.	Suh, Mina: 2 articles (08/2015 - 05/2014)
8.	Harris, Mark A: 2 articles (08/2015 - 05/2014)
9.	Haws, Laurie C: 2 articles (08/2015 - 05/2014)
10.	Madison, Blair B: 2 articles (08/2015 - 10/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Intestinal Neoplasms:

1.	BombesinIBA 08/15/1994 - "Although the combined use of DAP with bombesin had little or no influence on the location, size, histological features, or depth of involvement of intestinal cancers, the incidence of their metastasis was significantly reduced. " 01/01/2001 - "Although verapamil administered at either dose had little or no effect on the enhancement of intestinal carcinogenesis by bombesin or on the location, histologic type, depth of involvement, labeling index, apoptotic index or tumor vascularity of intestinal cancers, it significantly decreased the incidence of cancer metastasis. " 05/01/2000 - "Although genistein administered at either dose had little or no effect on the enhancement of intestinal carcinogenesis by bombesin or on the location, histologic type, depth of involvement, labeling index, or growth pattern of intestinal cancers, it significantly decreased the incidence of cancer metastasis. " 11/01/1997 - "Although administration of a higher dose of ginsenoside Rg3 with bombesin had little or no effect on the enhancement of intestinal carcinogenesis by bombesin, the location, histologic type, depth of involvement, infiltrating growth pattern, labeling and apoptotic indices and tumor vascularity of intestinal cancers, it significantly decreased the incidence of cancer metastasis. " 07/01/1996 - "Although administration of both doses of triamterene with bombesin had little or no influence on the enhancement of intestinal carcinogenesis by bombesin, or the location, histologic type, depth of invasion, or labeling index of intestinal cancers, it significantly reduced the incidence of cancer metastasis. "
2.	Dimenhydrinate (DMH)FDA LinkGeneric 02/01/1988 - "Mouse intestinal cancer induced by DMH injection are also shown to have an increased beta-G activity. " 02/20/2015 - "Here, we employed several complementary mouse models of intestinal cancers, including the Slit2 transgenic mice, the ApcMin/+ spontaneous intestinal adenoma mouse model, and the DMH/DSS-induced colorectal carcinoma model to clarify function of Slit2/Robo1 signaling in intestinal tumorigenesis. " 01/01/2008 - "At the end of 6 weeks of treatments, the results indicated significant alterations in the biochemical parameters, membrane lipid composition, and membrane fluorescence studies of the intestine in the presence of DMH, which were recovered nearly to the control level and, therefore, may suggest the chemopreventive efficacy of etoricoxib against the experimental intestinal cancer in rats." 09/01/2008 - "The results indicated a significant alteration in the enzyme activity as well as changes in the structure and function of the intestine in the presence of the pro-carcinogen, DMH, which suggests the possible chemopreventive efficacy of NSAIDs against the intestinal cancer." 04/01/1989 - "This study examines the effects of the excision of the forestomach (rumen), a squamous epithelial pouch of the rat, on the incidence and distribution of intestinal neoplasms induced by 1,2-dimethylhydrazine (DMH). "
3.	AzoxymethaneIBA 03/01/1989 - "A treatment regimen of 2% Na-InsP6 in drinking water was effective in significantly reducing large intestinal cancer in F344 rats even when the treatment was begun 5 months after carcinogenic induction with azoxymethane (AOM 8 mg/kg/wk X 6). " 02/01/2007 - "Male Sprague-Dawley rats were fed an AIN-76A-based diet for 4 weeks and intestinal neoplasms were induced by azoxymethane. " 07/01/1982 - "Combined inhibitors of carcinogenesis: effect on azoxymethane-induced intestinal cancer in rats." 12/01/1979 - "Promotion of azoxymethane-induced intestinal cancer by high-fat diet in rats." 09/01/1973 - "Pathology of intestinal neoplasms and other lesions in rats exposed to azoxymethane."
4.	SeleniumIBA 02/01/2002 - "This study investigated whether selenium-enriched broccoli would be protective against intestinal cancer susceptibility in Min mice. " 09/01/1997 - "The human epidemiological evidence is less clear cut, but overall suggests that selenium may be protective: the evidence is strongest in men in relation to gastro-intestinal cancers. " 06/01/1996 - "Rats receiving 4 ppm selenium had a relatively decreased incidence of intestinal cancer (from 65.8 percent (Group A) to 44.4 percent (Group C) and 47.1 percent (Group E) but P > 0.05). " 06/01/1996 - "Rats of Groups B and D received 8 ppm selenium and had a significantly decreased incidence of intestinal cancer (from 65.8 percent (Group A) to 33.3 percent (Group B) and 27.8 percent (Group D); P = 0.0225 and 0.0038). " 06/01/1996 - "Effect of selenium on 1,2-dimethylhydrazine-induced intestinal cancer in rats."
5.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 03/01/2008 - "The study, therefore, suggests a possible mechanism for the chemopreventive effects of NSAIDs against the experimental intestinal cancer in rats." 04/01/1999 - "Inflammatory bowel disease (IBD) patients, in particular, are sensitive to the adverse side effects of NSAIDs, and these patients also have an increased risk for the development of intestinal cancer. " 09/01/2008 - "The results indicated a significant alteration in the enzyme activity as well as changes in the structure and function of the intestine in the presence of the pro-carcinogen, DMH, which suggests the possible chemopreventive efficacy of NSAIDs against the intestinal cancer."
6.	Prostaglandins E (PGE)IBA 05/01/2008 - "In the present study, we evaluated the chemopreventive efficacy of targeting the terminal synthase microsomal PGE(2) synthase 1 (mPGES-1), which is responsible for generating PGE(2), in two murine models of intestinal cancer. " 01/01/2011 - "Based on our findings we suggest that PGE(2) act through PKA to promote β-catenin nuclear translocation and tumor development in Apc(Min/+) mice in vivo, indicating that the direct regulatory effect of PKA on β-catenin nuclear translocation is operative in intestinal cancer."
7.	Paclitaxel (Taxol)FDA LinkGeneric 10/01/2013 - "This study aimed to test the antiproliferative effect of three benzimidazole anthelmintics in intestinal cancer cells and to investigate whether these drugs, which inhibit tubulin polymerization, can potentiate the efficacy of the microtubule-stabilizing drug paclitaxel (PTX). "
8.	TubulinIBA 10/01/2013 - "This study aimed to test the antiproliferative effect of three benzimidazole anthelmintics in intestinal cancer cells and to investigate whether these drugs, which inhibit tubulin polymerization, can potentiate the efficacy of the microtubule-stabilizing drug paclitaxel (PTX). "
9.	AnthelminticsIBA 10/01/2013 - "This study aimed to test the antiproliferative effect of three benzimidazole anthelmintics in intestinal cancer cells and to investigate whether these drugs, which inhibit tubulin polymerization, can potentiate the efficacy of the microtubule-stabilizing drug paclitaxel (PTX). " 10/01/2013 - "Antiproliferative effect of benzimidazole anthelmintics albendazole, ricobendazole, and flubendazole in intestinal cancer cell lines."
10.	etoricoxibIBA 01/01/2008 - "At the end of 6 weeks of treatments, the results indicated significant alterations in the biochemical parameters, membrane lipid composition, and membrane fluorescence studies of the intestine in the presence of DMH, which were recovered nearly to the control level and, therefore, may suggest the chemopreventive efficacy of etoricoxib against the experimental intestinal cancer in rats."

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 11/01/2010 - "We reported that S-1 and UFT/LV therapy was effective with the two cases as an oral chemotherapy for the primary small intestinal cancer." 11/01/2010 - "However, there were a few case reports about chemotherapy for advanced or recurrent small intestinal cancer, and a treatment resume was inconsistent. " 03/01/1981 - "Patient attitudes to chemotherapy for advanced gastro-intestinal cancer." 12/01/1978 - "[Chemotherapy in intestinal cancer]." 08/24/1978 - "Chemotherapy studies in autochthonous rat tumors intestinal cancer."
2.	Cholecystectomy 12/01/2012 - "The association in this study, between cholecystectomy and intestinal cancer, is very unlikely to be causal. " 12/01/2012 - "Association between cholecystectomy and intestinal cancer: a national record linkage study." 12/01/2012 - "Some investigators have suggested that cholecystectomy increases the risk of intestinal cancer. " 09/01/2001 - "Cholecystectomy increases the risk of intestinal cancer, a risk that declines with increasing distance from the common bile duct. " 09/01/2001 - "Intestinal cancer after cholecystectomy: is bile involved in carcinogenesis?"
3.	Ostomy 03/01/2003 - "[Non-verbal communication of patients with intestinal cancer treated with ostomy]." 01/01/1996 - "Sixty-nine patients with gastro-intestinal cancer and 20 patients with ostomies due to Crohn's disease or ulcerative colitis participated in the study. "
4.	Transplantation (Transplant Recipients) 12/01/1950 - "Study on transplantation of Tanaka's rabbit-hepatoma and intestinal cancer by the transfusion of blood."
5.	Ileostomy 11/01/2013 - "Two hundred and fifty-one patients were recruited for the study; the mean age was 62 years, 58% were men, 72% had colostomy and 25% ileostomy; approximately 70% of patients had intestinal cancer requiring a stoma, 13% a complication and 10% an inflammatory disease. "