Intertrigo

A superficial dermatitis occurring on skin surfaces in contact with each other, such as the axillae, neck creases, intergluteal fold, between the toes, etc. Obesity is a predisposing factor. The condition is caused by moisture and friction and is characterized by erythema, maceration, burning, and exudation.

Networked: 54 relevant articles (2 outcomes, 7 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neck Pain (Cervicalgia)
2.	Shoulder Pain
3.	Ulnar Nerve Compression Syndromes (Ulnar Nerve Entrapment)
4.	Low Back Pain (Lumbago)
5.	Pain (Aches)

Experts

1.	Strumia, Renata: 3 articles (01/2013 - 01/2005)
2.	Wolf, Ronni: 2 articles (03/2011 - 08/2003)
3.	Mistiaen, Patriek: 2 articles (01/2010 - 02/2004)
4.	De Britto, Lourduraj John: 1 article (12/2015)
5.	Yuvaraj, Jayaram: 1 article (12/2015)
6.	Vijayalakshmi, Gnanasekaran: 1 article (12/2015)
7.	Poopathy, Subbiah: 1 article (12/2015)
8.	Kamaraj, Pattabi: 1 article (12/2015)
9.	Diop, A: 1 article (11/2015)
10.	Dicko, A: 1 article (11/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Intertrigo:

1.	Miconazole (Monistat)FDA LinkGeneric 02/01/2007 - "A paste enriched or not with miconazole nitrate is indicated to prevent or treat most presentations of intertrigo." 04/01/1990 - "Problems with clinical trials in general practice--a double-blind comparison of cream containing miconazole and hydrocortisone with hydrocortisone alone in the treatment of intertrigo."
2.	Copper Sulfate (Sulfate, Copper)FDA Link 07/01/2013 - "In this phase III open labeled, multicenter, non-controlled, non-randomized trial, irritant dermatitis in children and adults either due to diaper rash, pityriasis alba and irritant dermatitis (eczema), perioral dermatitis, perleche or intertrigo were administered; repairing cream RV 2427 B containing a) 4 % zinc oxide, b) 2.5 % dry colloidal oat extract, (c) 0.5 % oat oil, (d) 0.2% copper sulfate, and (e) 0.1 % zinc sulfate to be applied twice-daily in the affected area. "
3.	Zinc SulfateFDA Link 07/01/2013 - "In this phase III open labeled, multicenter, non-controlled, non-randomized trial, irritant dermatitis in children and adults either due to diaper rash, pityriasis alba and irritant dermatitis (eczema), perioral dermatitis, perleche or intertrigo were administered; repairing cream RV 2427 B containing a) 4 % zinc oxide, b) 2.5 % dry colloidal oat extract, (c) 0.5 % oat oil, (d) 0.2% copper sulfate, and (e) 0.1 % zinc sulfate to be applied twice-daily in the affected area. "
4.	Zinc OxideFDA Link 07/01/2013 - "In this phase III open labeled, multicenter, non-controlled, non-randomized trial, irritant dermatitis in children and adults either due to diaper rash, pityriasis alba and irritant dermatitis (eczema), perioral dermatitis, perleche or intertrigo were administered; repairing cream RV 2427 B containing a) 4 % zinc oxide, b) 2.5 % dry colloidal oat extract, (c) 0.5 % oat oil, (d) 0.2% copper sulfate, and (e) 0.1 % zinc sulfate to be applied twice-daily in the affected area. "
5.	Hydrocortisone (Cortisol)FDA LinkGeneric 04/01/1990 - "Problems with clinical trials in general practice--a double-blind comparison of cream containing miconazole and hydrocortisone with hydrocortisone alone in the treatment of intertrigo."
6.	DisinfectantsIBA 02/01/2004 - "Most studies concerned treatments with antifungals or disinfectants in heterogeneous research samples, with only small subsamples of people with intertrigo. "
7.	CosmeticsIBA 11/01/2015 - "Multivariate analysis showed the following to be independent risk factors associated with leg erysipelas in our study: obesity (odds ratio [OR]=2.82 ; 95% confidence interval: 2.11-3.76), lymphoedema (OR=3.87, 95%CI: 2.17-6.89), voluntary cosmetic depigmentation (OR=4.29, 95%CI: 2.35-7.83), neglected traumatic wound (OR=37.2, 95%CI: 24.9-57.72) and toe-web intertrigo (OR=37.86, 95%CI: 22.27-64.5). "
8.	Amphotericin B (Amphotericin)FDA LinkGeneric 12/01/1965 - "Amphotericin B lotion in monilial intertrigo: a double-blind paired comparison study."
9.	potashIBA 01/01/1986 - "The purpose of this study was to determine the clinical, epidemiological and evolutive characteristics of interdigital and plantar intertrigo of the feet among people working in a coking plant, a potash mine and a motorcar factory. "
10.	GigantomastiaIBA 04/01/2008 - "Macromastia causes back and neck pain, scaphodynia, intertrigo of the inframammary crease up to dysaesthesia. " 11/01/2009 - "Macromastia can be a morbid condition causing affected women to endure shoulder pain, back pain, intertrigo, and shoulder grooving from the bra straps. " 01/01/2010 - "In patients with macromastia, the currently accepted indications for reduction mammaplasty are back pain, neck pain, shoulder grooving, and intertrigo in the inframammary fold. "

Therapies and Procedures

1.	Mammaplasty (Breast Reconstruction) 01/01/2010 - "There is weak evidence that reduction mammaplasty may be helpful to treat inframammary intertrigo. " 04/01/2008 - "Conclusions based on the medical literature regarding volume of reduction, symptom presentation, conservative therapy, obesity, presence of bra strap grooving and intertrigo, and age at time of reduction were formulated, and these conclusions were compared with the criteria of 90 different health insurance reduction mammaplasty medical policies. " 01/01/1993 - "Reduction mammoplasty can provide relief from shoulder grooving, back and neck pain, intertrigo, and symptoms of ulnar nerve compression. " 05/01/2001 - "Reduction mammaplasty was associated with a statistically significant improvement in physical signs and symptoms involving shoulder pain (RD, 0.71 [95% confidence interval (CI), 0.62-0.80]); shoulder grooving (RD, 0.69 [95% CI, 0.60-0.78]); upper/lower back pain (RD, 0.59 [95% CI, 0.48-0.70]); neck pain (RD, 0.50 [95% CI, 0.37-0.64]); intertrigo (RD, 0.44 [95% CI, 0.34-0.54]); breast pain (RD, 0.36 [95% CI, 0.17-0.55]); headache (RD, 0.28 [95% CI, 0.11-0.46]); and pain/numbness in the hands (RD, 0.11 [95% CI, 0.04-0.18]). " 01/01/2010 - "In patients with macromastia, the currently accepted indications for reduction mammaplasty are back pain, neck pain, shoulder grooving, and intertrigo in the inframammary fold. "
2.	Protective Gloves 06/20/1992 - "Despite the high rates of dermatoses found in a study of 686 female workers in a canning factory in March 1990, use of protective gloves was extremely low, even though there was evidence that they prevented acute paronychia and intertrigo. "
3.	Catheters 01/01/2010 - "An alternative peritoneal catheter exit-site location is sometimes needed in patients with obesity, floppy skin folds, intestinal stomas, urinary and fecal incontinence, and chronic yeast intertrigo. "
4.	Antibiotic Prophylaxis 12/01/2015 - "From a public health perspective, LE patients of grades III and IV and patients under antibiotic prophylaxis should be self-motivated to look for the early symptoms of toe web intertrigo to prevent chronic stage and recurrent episodes of cellulitis. "