Inosine Triphosphate (ITP)

05/01/2008 - "Several recent studies have suggested that an association exists between Helicobacter pylori (HP) eradication and improvement in platelet count in a significant proportion of patients with idiopathic thrombocytopenic purpura (ITP). "
02/01/1981 - "A significant reduction in the proportion and absolute number of circulating T gamma (suppressor) lymphocytes was observed in 15 adult patients with idiopathic thrombocytopenic purpura (ITP). "
04/01/2001 - "When a patient is steroid-dependant, a currently available strategy in chronic idiopathic thrombocytopenic purpura (ITP) is to follow a trial and error approach with any of the known drugs which has been found effective in the condition. "
08/01/1996 - "Clinical studies employing patients presenting with idiopathic thrombocytopenic purpura (ITP) indicate that this new form of therapy is effective in approximately 40% of treated patients. "
08/01/2009 - "Helicobacter pylori eradication is useful for improvement of a half of patients with idiopathic thrombocytopenic purpura (ITP), but its long-term therapeutic efficacy has not been elucidated. "

01/01/2015 - "Most children with immune thrombocytopenia (ITP) will have spontaneous remission regardless of therapy, while about 20% will go on to have chronic ITP. "
10/01/2010 - "For most women with ITP, pregnancy is uncomplicated, and even those with severe thrombocytopenia during pregnancy have good outcomes when under the strict care of a hematologist and gynecologist."
05/01/2015 - "pylori is an effective and durable first line treatment for persistent or chronic ITP with moderate thrombocytopenia with high ORR and rapid onset in this study."
01/01/1994 - "The spleen acts as a major site of clearance of antibody-coated platelets from circulation in immune thrombocytopenia (ITP). "
04/01/2003 - "When activity of these disorders is low, standard treatments for ITP are effective for thrombocytopenia. "

01/01/1992 - "In one case, remission of AIHA allowed the donor's PBMC to successfully reconstitute SCID mice, despite the fact that the donor had developed immune thrombocytopenic purpura (ITP). "
02/01/2007 - "Immune thrombocytopenic purpura diagnosed in adolescence is more likely to be chronic then in childhood ITP, but has a higher rate of spontaneous resolution than in adults. "
12/01/2006 - "Recurrent immune thrombocytopenic purpura (ITP) is defined as the recurrence of ITP after at least 3 months of remission sustained without treatment. "
10/06/2008 - "To determine whether Helicobacter pylori eradication is an effective treatment for Australian patients with chronic immune thrombocytopenic purpura (ITP). "
08/01/2008 - "Corticosteroid (CS) therapy is effective in many patients with immune thrombocytopenic purpura (ITP), although it is associated with adverse effects. "

06/01/2014 - "Reaching a consensus for the management of paediatric ITP is further complicated by the lack of a diagnostic test and by the heterogeneity of the disease; for example, although most children remain relatively asymptomatic and go into an early remission, some patients have significant bleeding and others do not go into spontaneous remission. "
04/01/2003 - "The management of the bleeding symptoms without the adverse effects is an important point of steroid medication in ITP after first line treatment."
01/01/2009 - "The present report describes a 73-year-old patient with acute ITP who experienced diffuse alveolar hemorrhage that responded well to high-dose intravenous immunoglobulin therapy combined with corticosteroid pulse therapy."
06/01/1998 - "Suggested areas for study were grouped into five main areas: (i) improved classification of ITP identifying subsets of patients with differing clinical syndromes and response to treatment, and those more likely to have serious bleeding manifestations; identification of patients with reduced thrombopoiesis was emphasized; (ii) studies aimed at elucidating the aetiology and pathophysiology of ITP, with emphasis on distinctions between acute and chronic ITP and between patients responsive or refractory to therapy; these studies focused on measures of humoral and cellular immune dysregulation; (iii) studies of platelet function in ITP, with the intent of defining these abnormalities and correlating them with the clinical manifestations of the disease; (iv) new approaches to treatment, particularly of refractory patients; and (v) a miscellaneous group, which included development of an ITP registry, evaluation of the "burden" of disease, investigation of mood changes in ITP, etc. The discussion was not intended to be all-inclusive, but focused on the content of other talks in this symposium. "
01/01/1988 - "PE combined with IVGG may be a useful treatment for some patients with refractory ITP who have uncontrollable bleeding or require major surgery. "

06/01/1984 - "Acute ITP following infection in children has a high rate of spontaneous remission. "
06/01/2007 - "pylori status, and if present, infection should be eradicated before initiating a drastic conventional ITP treatment. "
08/01/2002 - "H.pylori eradication was obtained in 19 of 19 infected ITP patients (100%), who were not in remission (platelets < 100 x 109/l) at the time of infection assessment. "
12/01/2000 - "Our results suggest that menstruation, infection, and risk factors for progression to SLE may help to predict ICH in children with ITP. "
01/01/2015 - "The aim of this study was to assess the adjusted CS risk function of severe infection in persistent or chronic primary ITP adults. "