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Infectious Bovine Rhinotracheitis

Subscribe to New Research on Infectious Bovine Rhinotracheitis

A herpesvirus infection of CATTLE characterized by INFLAMMATION and NECROSIS of the mucous membranes of the upper RESPIRATORY TRACT.

Also Known As:

Bovine Rhinotracheitides, Infectious; Bovine Rhinotracheitis, Infectious; Infectious Bovine Rhinotracheitides; Rhinotracheitides, Infectious Bovine; Rhinotracheitis, Infectious Bovine

Networked: 153 relevant articles (5 outcomes, 9 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Diarrhea
2.	Infection
3.	Paramyxoviridae Infections (Parainfluenza)
4.	Vulvovaginitis
5.	Brucellosis (Malta Fever)

Experts

1.	Ferrari, M: 2 articles (01/2002 - 07/2000)
2.	Castrucci, G: 2 articles (01/2002 - 07/2000)
3.	Frigeri, F: 2 articles (01/2002 - 07/2000)
4.	Salvatori, D: 2 articles (01/2002 - 07/2000)
5.	Bovine Respiratory Disease Complex Coordinated Agricultural Project Research Team: 1 article (01/2015)
6.	Schnabel, Robert D: 1 article (01/2015)
7.	Toaff-Rosenstein, Rachel: 1 article (01/2015)
8.	Kim, JaeWoo: 1 article (01/2015)
9.	Taylor, Jeremy F: 1 article (01/2015)
10.	Van Eenennaam, Alison L: 1 article (01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Infectious Bovine Rhinotracheitis:

1.	VaccinesIBA 08/07/1982 - "Safety and efficacy of live and inactivated infectious bovine rhinotracheitis vaccines." 12/01/1971 - "Comparative efficacy of intranasally and parenterally administered infectious bovine rhinotracheitis vaccines." 04/01/2009 - "Serological response in cattle immunized with inactivated oil and Algel adjuvant vaccines against infectious bovine rhinotracheitis." 11/01/1996 - "Conventional vaccines are widely used to prevent clinical signs of infectious bovine rhinotracheitis. " 01/01/1996 - "Serological responses in calves to vaccines against bovine respiratory syncytial, infectious bovine rhinotracheitis, bovine viral diarrhoea and parainfluenza-3 viruses."
2.	Aprotinin (Trasylol)FDA Link 12/13/2002 - "This study evaluated the antiviral effect of various dosage forms of proteinase inhibitor-aprotinin as a potential remedy for prophylactics and therapy of infectious bovine rhinotracheitis. "
3.	Dosage Forms (Dosage Form)IBA 12/13/2002 - "This study evaluated the antiviral effect of various dosage forms of proteinase inhibitor-aprotinin as a potential remedy for prophylactics and therapy of infectious bovine rhinotracheitis. "
4.	Neutralizing AntibodiesIBA 10/01/1983 - "A survey of the age-specific BHV 1 neutralizing antibody pattern may be helpful for tracing animals and herds at risk of an outbreak of infectious bovine rhinotracheitis." 10/01/1987 - "To determine whether consumption of colostrum with high levels of serum neutralizing antibody to bovine herpesvirus 1 would protect neonatal calves from the frequently fatal multisystemic form of infectious bovine rhinotracheitis, Holstein calves were fed for 48 h after birth with either pooled colostrum from seropositive vaccinated cows or colostrum from seronegative unvaccinated cows. " 01/01/1985 - "Vaccinated calves developed neutralizing antibodies but did not show clinical signs of infectious bovine rhinotracheitis (IBR). " 12/01/1983 - "Serum samples (n = 1,146) representing 100 species of exotic ruminants now captive in United States zoos were assayed for neutralizing antibody to infectious bovine rhinotracheitis (IBR) virus (bovine herpesvirus 1). " 07/01/1973 - "The prevalence of neutralizing antibodies to infectious bovine rhinotracheitis (IBR) in cattle in Alberta."
5.	AntigensIBA 03/01/2012 - "These results reinforce previous findings that HSV-1 amplicon vectors can potentially deliver antigens to animals and highlight the prospective use of these vectors for treating infectious bovine rhinotracheitis disease." 01/01/1996 - "Moderate numbers of infectious bovine rhinotracheitis (IBR) virus antigens were also detected in degenerating and necrotizing parenchymal cells in various organs and correlated with distribution of intranuclear inclusion bodies. " 03/21/1992 - "Of 64 calves examined for bovine virus diarrhoea (BVD) and infectious bovine rhinotracheitis (IBR) antigens, two were positive for BVD virus and none for IBR virus. " 02/01/1987 - "Highly sensitive antigen detection procedures for the diagnosis of infectious bovine rhinotracheitis: amplified ELISA and reverse passive haemagglutination." 07/01/1986 - "Evidence indicated that there may be minimal or no cross-reactivity of IRIA antigen with anti-infectious bovine rhinotracheitis sera. "
6.	AntibodiesIBA 10/01/1983 - "A study of the dynamics of the production of class-specific antibodies to infectious bovine rhinotracheitis (IBR) virus in calves using a solid-phase radioimmunoassay." 07/01/2013 - "Ovine sera collected in the Prefectures of Hokkaido, Aomori and Iwate in the Northern Japan were examined for the presence of antibodies against Respiratory syncytial virus (RSV), bovine Herpesvirus type 1 (infectious bovine rhinotracheitis: IBR) and Parainfluenza virus type 3 (PIV3) using serum neutralisation (SN) and enzyme-linked immunosorbent assay (ELISA) tests. " 04/01/2000 - "The vulnerability of cattle populations that do not have adequate levels of antibodies against the bovine virus diarrhoea (BVD) virus was demonstrated in February 1999, when a contaminated vaccine against infectious bovine rhinotracheitis (IBR) was accidentally used. " 10/01/1997 - "The relative variability of the sero-prevalence of antibodies to infectious bovine rhinotracheitis (IBR) due to cow, farm, and agroecological area levels were investigated for three contrasting districts in Kenya: Samburu, an arid and pastoral area; Kiambu, a tropical highland area; and Kilifi, a typical tropical coastal area. " 09/01/1996 - "Antibodies reacting in the virus-neutralisation test with bovine herpesvirus (BHV-1), the causative agent of infectious bovine rhinotracheitis (IBR), were demonstrated in a herd of red deer (Cervus elaphus) imported into the Czech Republic. "
7.	Glycoproteins (Glycoprotein)IBA 11/01/2013 - "In the present study, serology, virus isolation, histopathology, immunohistochemistry (IHC) and real-time polymerase chain reaction (PCR) for amplification of the gene encoding glycoprotein B were applied for diagnosis of infectious bovine rhinotracheitis (IBR) in cases of abortion. " 08/12/2000 - "Four groups of calves were vaccinated with a glycoprotein E-negative vaccine for infectious bovine rhinotracheitis. " 08/12/2000 - "Early immunity induced by a glycoprotein E-negative vaccine for infectious bovine rhinotracheitis." 11/08/2011 - "To develop a novel vaccine against infectious bovine rhinotracheitis (IBR), a bovine herpesvirus-1 (BoHV-1) mutant was constructed by deleting the genes for glycoprotein G (gG) and thymidine kinase (tk) through homologous recombination. " 04/19/1999 - "In the context of infectious bovine rhinotracheitis (IBR) control programmes using glycoprotein E (gE) deleted marker vaccines, a PCR assay was developed to allow the genotypic differentiation between wildtype bovine herpesvirus type 1 (BoHV-1) and gE negative strains. "
8.	DNA Restriction Enzymes (Restriction Endonuclease)IBA 01/01/1981 - "Comparison of the genomes of infectious bovine rhinotracheitis and infectious pustular vulvovaginitis virus strains by restriction endonuclease analysis." 01/01/1984 - "Three strains (479 C, 778 TL, 982 LE) of infectious bovine rhinotracheitis (IBR) virus isolated from latently infected calves were compared with the prototype strain of IBR virus (LA strain) in studies which included restriction endonuclease analysis, experimental infection, and reciprocal cross protection tests in cattle. " 01/01/1985 - "Infectious Bovine Rhinotracheitis (IBR) and Infectious Pustular Vulvovaginitis (IPV) virus strains of Bovine Herpesvirus 1 (BHV-1) can be differentiated by restriction endonuclease digestion of their DNAs. " 08/01/1986 - "Viral DNA from isolates obtained from 6 field samples of IBRV (1 from Colorado, 1 from West Virginia, 3 from Wisconsin, 1 from South Dakota) were digested with restriction endonucleases, and patterns were compared to evaluate the role of vaccinal virus in these field epizootics of infectious bovine rhinotracheitis. " 08/01/1986 - "Investigation of possible vaccine-induced epizootics of infectious bovine rhinotracheitis, using restriction endonuclease analysis of viral DNA."
9.	Octoxynol (Triton X 100)IBA 04/01/1986 - "Trials were conducted on rabbits and cattle to compare the immunizing effectiveness of the subunit vaccine against infectious bovine rhinotracheitis (IBR), representing antigens separated by the solubilization of the IBR virus-infected cells by means of Triton X-100 with oil adjuvant, with the inactivated oil IBR vaccine. " 03/01/1980 - "Subunit infectious bovine rhinotracheitis (IBR) antigens were prepared by solubilization of IBR-virus infected cell cultures with nonionic detergents Triton X-100 and NP-40. "
10.	ChromiumIBA 04/01/1994 - "Effects of supplemental chromium on antibody responses of newly weaned feedlot calves to immunization with infectious bovine rhinotracheitis and parainfluenza 3 virus." 04/01/1996 - "Two trials were conducted to investigate the effects of supplemental chromium (Cr) from organic sources (Cr chelate and high Cr yeast) on antibody responses of newly arrived feeder calves following vaccination with infectious bovine rhinotracheitis (IBR), para-influenza-3 (PI3), bovine respiratory syncytial virus (BRSV), bovine viral diarrhea (BVD) and Pasteurella haemolytica and ovalbumin (OVA). "

Therapies and Procedures

1.	Injections 01/01/1986 - "At wk 12, serum from calves given the high amount of oral supplementation and calves given injections inhibited infectious bovine rhinotracheitis viral replication in tissue cultures as compared with those of unsupplemented calves. " 12/01/2000 - "Horses received 2 IM injections at 2-week intervals of a vaccine containing inactivated infectious bovine rhinotracheitis, bovine viral diarrhea, and parainfluenza-3 viral antigens and were then randomly assigned to 2 groups. " 07/01/1979 - "Infectious bovine rhinotracheitis/infectious pustular vulvovaginitis (IBR/IPV) is probably a venereal disease because virgin wildebeest did not develop vulvovaginitis after betamethasone injections, nor was the virus transmitted to these virgin wildebeest and steers which were in pen contact with the affected animals. " 02/01/2009 - "On May 19, 2006 (d 0), steers were administered one of the following treatment injections: a standard Biobullet containing 100 mg of ceftiofur sodium (Naxel, Pfizer Inc., New York, NY); a traditional needle and syringe dose of ceftiofur sodium; a standard Biobullet containing BallistiVac infectious bovine rhinotracheitis (IBR; Titanium 5, SolidTech Animal Health, Newcastle, OK); a traditional needle and syringe dose of IBR; a traditional needle and syringe dose of Vira Shield 5 (Grand Laboratories Inc., Freeman, SD); a standard placebo Biobullet; or a traditional needle and syringe dose of sterile water. "
2.	Intramuscular Injections 04/01/1994 - "The calves had received an intramuscular injection of modified-live infectious bovine rhinotracheitis parainfluenza-3 vaccine between birth and three days of age. " 05/01/1990 - "Nineteen nulliparous, sexually mature heifers free of antibody to infectious bovine rhinotracheitis (IBR) virus were given two 35 mg intramuscular injections of Lutalyse 10 days apart to synchronize estrus and randomly divided into control and vaccinated groups. "
3.	Nebulizers and Vaporizers (Inhaler) 04/01/1984 - "Four calves (control animals) were inoculated (by aerosol) with Cooper's strain of infectious bovine rhinotracheitis (IBR) virus given with an ultrasonic nebulizer. "
4.	Aftercare (After-Treatment) 01/01/1983 - "A group of 463 calves, kept under one and the same conditions of tending and feeding, were followed up from the fifteenth day after birth up to one year of age, after treatment by subgroups with a hyperimmune antibovine rabbit serum, biomass of chlorella, a tissue preparation of swine embryos, and vaccines against mucosal diseases and infectious bovine rhinotracheitis. "
5.	Intranasal Administration 08/07/1982 - "Two commercial live virus infectious bovine rhinotracheitis (IBR) vaccines for intranasal administration and an inactivated polyvalent calf pneumonia vaccine were compared for safety and efficacy in calves against experimental IBR infections. "