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Immunoglobulin Fc Fragments

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Also Known As:
Immunoglobulin Fc Fragment; Immunoglobulins, Fc; Immunoglobulins, Fc Fragment; Fc Fragment Immunoglobulins; Fc Fragment, Immunoglobulin; Fc Fragments, Ig; Fc Fragments, Immunoglobulin; Fragment Immunoglobulins, Fc; Fragment, Fc; Fragments, Ig Fc; Immunoglobulin, Fc; Fc Fragment; Fc Fragments; Fc Immunoglobulin; Fc Immunoglobulins; Ig Fc Fragments
Networked: 295 relevant articles (18 outcomes, 33 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Beduleva, Liubov: 6 articles (10/2022 - 02/2017)
2. Menshikov, Igor: 6 articles (10/2022 - 02/2017)
3. Sidorov, Alexandr: 5 articles (10/2022 - 02/2017)
4. Terentiev, Alexey: 4 articles (10/2022 - 02/2017)
5. Lindhofer, Horst: 3 articles (01/2021 - 08/2012)
6. Ruf, Peter: 3 articles (01/2021 - 08/2012)
7. Seth, Prem: 3 articles (01/2019 - 11/2006)
8. Cherepanov, Igor: 2 articles (10/2022 - 03/2020)
9. Menshikova, Daria: 2 articles (10/2022 - 12/2021)
10. Liu, Wei: 2 articles (01/2022 - 01/2021)

Related Diseases

1. Autoimmune Diseases (Autoimmune Disease)
2. Myasthenia Gravis
3. Neoplasms (Cancer)
4. Infections
5. Hemophilia B (Haemophilia B)

Related Drugs and Biologics

1. Immunoglobulin G (IgG)
2. Immunoglobulins (Immunoglobulin)
3. Intravenous Immunoglobulins (IVIG)
4. Monoclonal Antibodies
5. Autoantibodies
6. Peptides (Polypeptides)
7. Factor IX (Coagulation Factor IX)
8. Complement C5 (Complement 5)
9. zilucoplan
10. rozanolixizumab

Related Therapies and Procedures

1. Therapeutics
2. Immunomodulation
3. Immunotherapy
4. Intravenous Administration
5. Intraventricular Infusions