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Immunoglobulin Variable Region

That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.
Also Known As:
Framework Region, Immunoglobulin; Fv Antibody Fragments; Fv Fragments; Ig Framework Region; Ig Variable Region; Immunoglobulin Framework Region; Immunoglobulin Fv Fragments; Immunoglobulin V; Antibody Fragment, Fv; Antibody Fragments, Fv; Fragment, Fv; Fragment, Fv Antibody; Fragment, Immunoglobulin Fv; Fragments, Fv; Fragments, Fv Antibody; Fragments, Immunoglobulin Fv; Framework Region, Ig; Framework Regions, Ig; Framework Regions, Immunoglobulin; Fv Antibody Fragment; Fv Fragment; Fv Fragment, Immunoglobulin; Fv Fragments, Immunoglobulin; Ig Framework Regions; Ig Variable Regions; Immunoglobulin Framework Regions; Immunoglobulin Fv Fragment; Immunoglobulin Variable Regions; Regions, Immunoglobulin Variable; Variable Regions, Ig; Variable Regions, Immunoglobulin; Variable Region, Ig; Variable Region, Immunoglobulin
Networked: 208 relevant articles (3 outcomes, 16 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Stevenson, Freda K: 9 articles (10/2021 - 02/2002)
2. Kreitman, Robert J: 6 articles (11/2014 - 10/2006)
3. Stott, David I: 5 articles (02/2014 - 01/2005)
4. Rosenquist, Richard: 5 articles (07/2005 - 04/2003)
5. Pastan, Ira: 4 articles (11/2014 - 10/2006)
6. Mehr, Ramit: 4 articles (02/2014 - 04/2006)
7. Ottensmeier, Christian H: 4 articles (03/2008 - 04/2002)
8. Sundström, Christer: 4 articles (07/2005 - 04/2003)
9. Thunberg, Ulf: 4 articles (07/2005 - 04/2003)
10. Forconi, Francesco: 3 articles (01/2022 - 12/2020)

Related Diseases

1. Neoplasms (Cancer)
2. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
3. Breast Neoplasms (Breast Cancer)
4. Neoplasm Metastasis (Metastasis)
5. Lymphoma (Lymphomas)

Related Drugs and Biologics

1. Disulfides
2. Transferrin Receptors (Transferrin Receptor)
3. Lipids
4. Immunotoxins (Immunotoxin)
5. Exotoxins
6. Antibodies
7. Peptides (Polypeptides)
8. Epitopes
9. Myeloma Proteins
10. Solvents

Related Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Drug Therapy (Chemotherapy)
4. Transjugular Intrahepatic Portasystemic Shunt