Hypothalamic Neoplasms

Benign and malignant tumors of the HYPOTHALAMUS. Pilocytic astrocytomas and hamartomas are relatively frequent histologic types. Neoplasms of the hypothalamus frequently originate from adjacent structures, including the OPTIC CHIASM, optic nerve (see OPTIC NERVE NEOPLASMS), and pituitary gland (see PITUITARY NEOPLASMS). Relatively frequent clinical manifestations include visual loss, developmental delay, macrocephaly, and precocious puberty. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2051)
Also Known As:
Benign Hypothalamic Neoplasms; Hypothalamic Cancer; Hypothalamic Neoplasms, Benign; Hypothalamic Neoplasms, Malignant; Hypothalamic Teratomas; Hypothalamo-Neurohypophysial Region Neoplasms; Hypothalamus Neoplasms; Malignant Hypothalamic Neoplasms; Neoplasms, Hypothalamic; Neoplasms, Hypothalamic, Benign; Neoplasms, Hypothalamic, Malignant; Neoplasms, Hypothalamic-Chiasmatic; Neoplasms, Hypothalamic-Pituitary; Neoplasms, Hypothalamo-Neurohypophysial Region; Neoplasms, Hypothalamus; Tumors, Hypothalamus; Benign Hypothalamic Neoplasm; Cancer, Hypothalamic; Cancers, Hypothalamic; Hypothalamic Cancers; Hypothalamic Chiasmatic Neoplasms; Hypothalamic Neoplasm; Hypothalamic Neoplasm, Malignant; Hypothalamic Pituitary Neoplasms; Hypothalamic Teratoma; Hypothalamic Tumor; Hypothalamic-Chiasmatic Neoplasm; Hypothalamic-Pituitary Neoplasm; Hypothalamo Neurohypophysial Region Neoplasms; Hypothalamo-Neurohypophysial Region Neoplasm; Hypothalamus Neoplasm; Hypothalamus Tumor; Hypothalamus Tumors; Malignant Hypothalamic Neoplasm; Neoplasm, Benign Hypothalamic; Neoplasm, Hypothalamic; Neoplasm, Hypothalamic-Chiasmatic; Neoplasm, Hypothalamic-Pituitary; Neoplasm, Hypothalamo-Neurohypophysial Region; Neoplasm, Hypothalamus; Neoplasm, Malignant Hypothalamic; Neoplasms, Hypothalamic Chiasmatic; Neoplasms, Hypothalamic Pituitary; Neoplasms, Hypothalamo Neurohypophysial Region; Neoplasms, Malignant Hypothalamic; Teratoma, Hypothalamic; Teratomas, Hypothalamic; Tumor, Hypothalamic; Tumor, Hypothalamus; Tumors, Hypothalamic; Hypothalamic Tumors; Hypothalamic-Chiasmatic Neoplasms; Hypothalamic-Pituitary Neoplasms
Networked: 39 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Precocious Puberty
2. Hamartoma
3. Teratoma (Teratoid Tumor)
4. Brain Neoplasms (Brain Tumor)
5. Necrosis


1. Müller, Hermann L: 3 articles (01/2011 - 08/2002)
2. Massimino, Maura: 2 articles (09/2012 - 03/2009)
3. Gebhardt, Ursel: 2 articles (01/2011 - 05/2006)
4. Kanbayashi, Takashi: 2 articles (09/2006 - 12/2004)
5. Sörensen, Niels: 2 articles (05/2006 - 08/2002)
6. Faldum, Andreas: 2 articles (05/2006 - 08/2002)
7. Handwerker, Georg: 2 articles (05/2006 - 08/2002)
8. Kawami, Takako: 1 article (11/2015)
9. Tungalagsuvd, Altankhuu: 1 article (11/2015)
10. Irahara, Minoru: 1 article (11/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hypothalamic Neoplasms:
1. Gonadotropin-Releasing Hormone (GnRH)FDA Link
2. 3- (2- carboxypiperazin- 4- yl)propyl- 1- phosphonic acid (CPP)IBA
3. Growth Hormone (Somatotropin)IBA
4. MelatoninIBA
5. Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA
6. ElectrolytesIBA
7. orexins (orexin)IBA
8. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
9. ProlactinIBA
10. GlucocorticoidsIBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Adjuvant Chemotherapy
3. Craniotomy
4. Radiotherapy
5. Neuroendoscopes