Controlled Hypotension

Procedure in which arterial blood pressure is intentionally reduced in order to control blood loss during surgery. This procedure is performed either pharmacologically or by pre-surgical removal of blood.

Also Known As:

Networked: 1570 relevant articles (56 outcomes, 122 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Shibamoto, Toshishige: 6 articles (05/2018 - 07/2007)
2.	Lahlou, Saad: 6 articles (01/2016 - 08/2002)
3.	Magalhães, Pedro Jorge Caldas: 5 articles (09/2020 - 08/2002)
4.	Kurata, Yasutaka: 5 articles (05/2018 - 07/2013)
5.	Tanida, Mamoru: 5 articles (05/2018 - 07/2013)
6.	Malik, Kafait U: 4 articles (01/2022 - 01/2012)
7.	Sahan-Firat, Seyhan: 4 articles (01/2022 - 01/2012)
8.	Sari, Ayse Nihal: 4 articles (01/2022 - 01/2012)
9.	Tunctan, Bahar: 4 articles (01/2022 - 01/2012)
10.	de Siqueira, Rodrigo José Bezerra: 4 articles (09/2020 - 10/2005)

Related Diseases

1.	Bradycardia 11/01/2019 - "When used as an intermittent bolus regimen to prevent and treat spinal-induced hypotension during CD, NE resulted in a significant reduction in the incidence of bradycardia as compared to an equipotent bolus regimen of PE. " 01/01/2018 - "We hypothesized that RIPC will provide protection against VVS-induced hypotension, bradycardia, and cerebral hypoperfusion. " 01/01/2023 - "Conclusion The present study concludes that BMI and the dose of SA were the factors associated with SA-induced hypotension during a CS, and the site of the SA puncture equal to or lower than L2 was the only risk factor associated with spinal anesthesia-induced bradycardia." 02/01/2018 - "The aim of our study was to determine the incidence and the risk factors for intraoperative bradycardia in maxillofacial, ear, nose and throat surgery, as well as to determine whether controlled hypotension affects the occurrence of IOB. " 01/01/2001 - "The objectives of our study were to determine whether a sympathoinhibitor depressor reflex, along with the bradycardia, is observed during pharmacologically induced hypotension in fetal and newborn lambs. "
2.	Hypotension (Low Blood Pressure) 12/01/2002 - "Therefore, we performed this study to evaluate the effect of normovolemic hypotension on characteristics of plethysmographic waveform in 33 adult patients undergoing general anesthesia with controlled hypotension. " 07/27/2023 - "When the ARM was repeated intraoperatively, a quarter of subjects developed ARM-related hypotension, but only 3.61% of ARMs induced hypotension. " 07/27/2023 - "Alveolar recruitment maneuvers (ARMs) may lead to transient hypotension, but the clinical characteristics of this induced hypotension are poorly understood. " 07/14/2023 - "The patients were divided into two groups: Controlled hypotension group (n = 48, MAP reduction to 55-65 mmHg, minimum of 60% of baseline blood pressure) or Individualized hypotension group (n = 48, MAP reduction to 75-80% of baseline blood pressure). " 01/01/2022 - "We report successful completion of planned PCI with blood pressure support with vasopressors during contrast-induced hypotension in nine procedures in three patients with previously known contrast reaction causing hypotension. "
3.	Sepsis (Septicemia) 11/01/2022 - "OLM markedly attenuated CLP-induced hypotension and organ injury, and hence improved survival by inhibiting the inflammatory response and nitrosative stress in this clinically relevant model of sepsis." 12/01/2023 - "This finding supports the conduct of clinical trials evaluating optimal fluid dose and vasopressor timing for early sepsis-induced hypotension." 01/01/2023 - "Among patients with sepsis-induced hypotension, the restrictive fluid strategy that was used in this trial did not result in significantly lower (or higher) mortality before discharge home by day 90 than the liberal fluid strategy. " 12/01/2023 - "Optimal resuscitation of sepsis-induced hypotension is uncertain, particularly the role of restrictive fluid strategies, leading to variability in usual practice. " 11/01/2023 - "We performed serial POC-Echo within 6 hours (h) of presentation and subsequently at 24, 48 and 72 h in patients with ACLF and sepsis-induced hypotension admitted to our liver intensive care unit. "
4.	Hemorrhage 05/19/2022 - "In the present study, the role of this nucleus in normotensive conditions and then the role of these receptors on cardiovascular function in hypotension induced by hemorrhage (HEM) were investigated. " 05/01/2019 - "In this study, the probable role of PPT on cardiovascular parameters in the hypotension induced by Hemorrhage (HEM) was evaluated. " 02/18/2000 - "The purpose of this study was to compare cerebral and cerebellar autoregulatory responses to hypotension induced by two rates of hemorrhage 1.5 and 2.0 ml/min. Cortical blood flows were measured simultaneously using laser Doppler flowmetry in rats. " 08/01/1999 - "In this study, c-fos expression was used to identify areas in the forebrain and brainstem of the domestic chicken that are activated following acute osmotic stress and hemorrhage-induced hypotension. " 07/20/1998 - "C-fos expression and electrolytic lesions studies reveal activation of the posterior region of locus coeruleus during hemorrhage induced hypotension."
5.	Tachycardia (Tachyarrhythmias) 01/01/2014 - "Bilateral passive leg raising attenuates and delays tourniquet deflation-induced hypotension and tachycardia under spinal anaesthesia: a randomised controlled trial." 11/01/2022 - "Moreover, OLM mitigated CLP-induced hypotension and organ injury (indicated by biochemical parameters), but not tachycardia. " 01/01/2020 - "ASM-/- mice were protected from TNF-induced hypotension and reflex tachycardia and also from mortality. " 04/01/2015 - "In SHRs, the hypotension induced by labd-8 is associated with a reflex tachycardia and seems mediated partly through withdrawal of sympathetic vasomotor tone and partly through an active vasorelaxation. " 02/15/2012 - "Differently from the hypotension induced by SNP, the action of TERPY was slow, long lasting and it did not lead to reflex tachycardia in both groups. "

Related Drugs and Biologics

1.	Nitroprusside (Sodium Nitroprusside)
2.	Phenylephrine (Neo-Synephrine)
3.	Ondansetron (Zofran)
4.	Acids
5.	Diltiazem (Cardizem)
6.	Ephedrine
7.	Dexamethasone (Maxidex)
8.	Albumins
9.	esmolol (Brevibloc)
10.	Clonidine (ST 155)

Related Therapies and Procedures

1.	Spinal Anesthesia
2.	Resuscitation
3.	Anesthesia
4.	Ligation
5.	Punctures