Chemical Hypophysectomy

Total or subtotal destruction of the pituitary gland by chemical injection. It is usually achieved by injection of ethyl alcohol via trans-sphenoidal cannulation under stereotaxic control. It is usually performed for the treatment of intractable pain.

Also Known As:

Networked: 14 relevant articles (0 outcomes, 0 trials/studies)

Therapy Context: Research Results

Experts

1.	Hayashi, Motohiro: 3 articles (01/2021 - 01/2003)
2.	Chernov, Mikhail: 2 articles (01/2005 - 01/2003)
3.	Hori, Tomokatsu: 2 articles (01/2005 - 01/2003)
4.	Izawa, Masahiro: 2 articles (01/2005 - 01/2003)
5.	Katayama, Yoko: 2 articles (01/2005 - 01/2003)
6.	Kawakami, Yoriko: 2 articles (01/2005 - 01/2003)
7.	Kouyama, Nobuo: 2 articles (01/2005 - 01/2003)
8.	Taira, Takaomi: 2 articles (01/2005 - 01/2003)
9.	Takakura, Kintomo: 2 articles (01/2005 - 01/2003)
10.	Chernov, Mikhail F: 1 article (01/2021)

Related Diseases

1.	Pain (Aches) 01/01/2003 - "In one report, the control of central pain (thalamic pain syndrome) was also approached with chemical hypophysectomy. " 12/01/1983 - "The mechanism of action of stereotaxic chemical hypophysectomy in the relief of pain related to thalamic lesions remains unknown. " 12/01/1983 - "Stereotaxic chemical hypophysectomy was used in the management of this pain after other surgical procedures and medical management had failed to provide relief. " 12/01/1983 - "The use of stereotaxic chemical hypophysectomy in the treatment of thalamic pain syndrome." 03/01/1980 - "[Chemical hypophysectomy for pain relief]."
2.	Cancer Pain 01/01/2003 - "Two or three decades ago, cancer pain was treated by surgical/chemical hypophysectomy. " 12/01/1978 - "[Chemical hypophysectomy for intractable cancer pain by Moricca--1. " 09/01/1980 - "[Chemical hypophysectomy in the treatment of cancer pain and metastases. " 01/01/1979 - "[Chemical hypophysectomy for the intractable cancer pain by Moricca -2. The results and the mechanism of pain relief (author's transl)]."
3.	Neoplasms (Cancer) 04/01/1984 - "Chemical hypophysectomy produced pain relief in over 75% of the patients, regardless of tumor type or hormonal dependence. " 04/01/1984 - "Thirteen series of patients who underwent surgical or chemical hypophysectomy for the relief of pain associated with cancer were reviewed. " 03/01/1980 - "Treatment of pain of diffuse metastatic cancer by stereotactic chemical hypophysectomy: long term results and observations on mechanism of action." 02/01/1977 - "The technique of "chemical hypophysectomy" was modified for the management of pain due to metastatic cancer. "
4.	Carcinoma (Carcinomatosis) 04/01/1978 - "Chemical hypophysectomy for relief of bone pain in carcinoma of the prostate." 01/01/1980 - "[Clinical effects of chemical hypophysectomy--instillation of ethanol into the pituitary on advanced prostatic carcinoma (author's transl)]."
5.	Intractable Pain 01/01/2021 - "Surgical or chemical hypophysectomy has historically shown good effectiveness in management of intractable pain but has often been accompanied by serious complications. "

Related Drugs and Biologics

1.	Ethanol (Ethyl Alcohol)

Related Therapies and Procedures

1.	Operative Surgical Procedures