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Malignant Hypertension

A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.
Also Known As:
Hypertension, Malignant
Networked: 859 relevant articles (38 outcomes, 61 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hypertension (High Blood Pressure)
2. Renal Insufficiency (Renal Failure)
3. Stroke (Strokes)
4. Hyperaldosteronism (Conn Syndrome)
5. Heart Failure

Experts

1. Mitchell, Kenneth D: 16 articles (10/2013 - 10/2005)
2. Mullins, John J: 14 articles (05/2011 - 02/2004)
3. Husková, Zuzana: 8 articles (01/2019 - 05/2009)
4. Kopkan, Libor: 8 articles (01/2019 - 01/2011)
5. van Montfrans, Gert A: 8 articles (04/2013 - 10/2004)
6. van den Born, Bert-Jan H: 7 articles (04/2013 - 10/2004)
7. Morales, Enrique: 6 articles (12/2019 - 12/2008)
8. Praga, Manuel: 6 articles (12/2019 - 12/2008)
9. Červenka, Luděk: 6 articles (10/2018 - 01/2011)
10. Kramer, Herbert J: 6 articles (10/2016 - 05/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Malignant Hypertension:
1. Antihypertensive Agents (Antihypertensives)IBA
2. mahuang-tangIBA
3. Captopril (Capoten)FDA LinkGeneric
4. CalciumIBA
5. Retinaldehyde (Retinal)IBA
6. Vasodilator Agents (Vasodilators)IBA
7. DiureticsIBA
8. EnzymesIBA
01/01/2022 - "It has been used to explore complement activation from sera of patients with atypical hemolytic uremic syndrome, malignant hypertension, elevated liver enzymes low platelet syndrome, sickle cell disease, pre-eclampsia, and others. "
06/01/2004 - "The clinical presentations were haemolytic-uraemic syndrome (26%), catastrophic APS (23%), acute renal failure (15%), malignant hypertension (13%), thrombotic thrombocytopenic purpura (13%), and HELLP (haemolysis, elevated liver enzymes, and low platelet count in association with eclampsia) syndrome (4%). "
12/06/2019 - "Patients with atypical hemolytic uremic syndrome (n=34) at different stages of the disease, HELLP syndrome (a pregnancy complication characterized by hemolysis, elevated liver enzymes, and low platelet count) or severe preeclampsia (n=10), and malignant hypertension (n=5) were included. "
06/01/2017 - "Complement-amplifying conditions (CACs), including pregnancy complications [preeclampsia, HELLP (hemolysis, elevated liver enzymes, low platelet count) syndrome], malignant hypertension, autoimmune diseases, transplantation, and others, are associated with the onset of TMA in up to 69 % of cases of aHUS. "
01/01/2019 - "Beyond them, differential diagnosis also includes TMAs associated with underlying conditions, such as drugs, malignancy, infections, scleroderma-associated renal crisis, systemic lupus erythematosus (SLE), malignant hypertension, transplantation, HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets), and disseminated intravascular coagulation (DIC). "
9. Nitric Oxide (Nitrogen Monoxide)FDA Link
10. Reserpine (Serpasil)FDA Link

Therapies and Procedures

1. Therapeutics
2. Nephrectomy
3. Renal Dialysis (Hemodialysis)
4. Transplantation
5. Sympathectomy (Sympathectomies)