Hypernatremia

11/22/2023 - "The functional bread was designed to be potentially effective in reducing hypernatremia condition which is indicative of high levels of sodium in serum that can cause an array of symptoms including deaths in serious cases. "
02/25/2022 - "PubMed, Ichushi-database, and references without language restrictions, from inception to January 2021, were searched for studies that described ≥1 adult (aged ≥18 years) patients with rapid-onset hypernatremia caused by sodium overload, whose treatment was initiated ≤12 hours from the onset. "
01/01/2022 - "In the 903 participants consisting of 273 women and 630 men who were enrolled in this study, the overall prevalence of hypernatremia, defined as a serum sodium level ≥145 mmol/L, was 12.5%. "
01/01/2022 - "This study aimed to describe the data regarding serum sodium level and hypernatremia prevalence and to investigate whether female sex is associated with an increased risk of hypernatremia. "
06/01/2021 - "We included studies comparing vaptans and placebo with data on hypernatremia and serum sodium overcorrection. "

01/01/1957 - "Studies on the electrolytes in organs in fatal cases of infantile hypernatremia."
09/01/2023 - "Aim of the article was to summarize data on both, epidemiology and outcomes of in-hospital acquired hypernatremia ("In-hospital acquired" refers to the diagnosis of either hypo- or hypernatremia in patients, who did not exhibit any of these electrolyte imbalances upon admission to the hospital). "
07/01/2023 - "Chronic hypernatremia should be considered in children with FTT with altered mental status, and the gradual correction of electrolytes should be performed to minimize patient harm."
01/01/2023 - "Hypernatremia is an occasionally encountered electrolyte disorder, which may lead to fatal consequences under improper management. "
10/01/2022 - "An imbalance of serum electrolyte concentrations including Na (hypernatremia), Ca (hypercalcaemia) and K (hypokalaemia) was also observed in MI patients in which CVDs risk factors were found to correlate positively with serum Na and Ca and negatively with serum K, respectively. "

12/01/2023 - "Enteral free water vs. parenteral dextrose 5% in water for the treatment of hypernatremia in the intensive care unit: a retrospective cohort study from a mixed ICU."
12/02/2020 - "Treating the DKA more aggressively than the hypernatremia itself, choosing a hypoosmolar fluid, and switching to D5-0.45% saline, when glucose has decreased, are some of the vital considerations for the management of hypernatremia in DKA. "
01/01/2019 - "The dog developed severe hypernatremia within six hours of presentation, which responded poorly to the administration of five percent dextrose in water. "
12/01/2000 - "Water loss associated with glucose diuresis may necessitate a higher rate of fluid administration in camelids with this syndrome than is typically used for treatment of hypernatremia in calves."
07/01/2016 - "The patient presented in this article had hypernatremia refractory to D5W (dextrose 5% water) therapy, which led to a complex investigation. "

09/01/2015 - "The use of isotonic solution (150 mEq/L, 0.9%) did not favor hypernatremia in these patients. "
02/01/2015 - "ENaC activity was elevated in mice that consumed 3% NaCl solution compared with mice that consumed a diet enriched in Na(+) with ad libitum tap water; the latter diet does not cause hypernatremia. "
02/01/2015 - "Consumption of a 3% NaCl solution induced hypernatremia and plasma hypertonicity in mice. "
03/01/2003 - "Patients who were rehydrated with a high-osmolarity solution showed symptoms of hypernatremia (serum Na(+) concentration >140 mEq/L). "
10/01/1989 - "Hyposaline and normo-osmol solution (Na+ 70 mEq/L) were used for one patient with hypernatremia and consciousness disturbance. "

12/01/1989 - "In the present study, 1H-nuclear magnetic resonance (NMR) spectroscopy and biochemical assays of rat brain were used to identify and quantify changes in organic solutes in two different animal models of hypernatremia: hypertonic salt loading and water deprivation. "
09/24/1977 - " Unfortunately in a recent study in 2 tropical countries, the 2-finger pinch technique of measuring the salt has been found to have an unacceptably wide variability and could result in cases of hypernatremia that would bring this invaluable treatment into disrepute. "
01/01/2023 - "Salt and Water: A Review of Hypernatremia."
01/01/2022 - "Patients with adipsic hypernatremia present with chronic hypernatremia because of defects in thirst sensation and dysregulated salt appetite, without demonstrable hypothalamic structural lesions. "
09/01/2020 - "The development of ICU-acquired hypernatremia (IAH) is almost exclusively attributed to 'too much salt and too little water'. "

04/01/1994 - "Hypernatremia is also a concern for malnourished children, but studies show that WHO's ORS is safe and effective in treating malnourished children. "
01/01/2016 - "Thus, managing children with hypernatremia using only ORS or ORS following intravenous fluid may help reduce the number of deaths."
04/01/2007 - "Compared to ORS II, ROORS could decrease the intravenous supplement of fluid and lower the risk of hypernatremia."
08/01/1996 - " The risk of hypernatremia with use of the WHO/UNICEF ORS is a concern since infants and young children have an immature renal concentrating capacity, increased insensible water losses, and an impaired natriuretic response. "
03/01/1995 - "Hypernatremia and ORS."

12/01/2016 - "The aim of this study was to determine demographic and clinical characteristics of the elderly hypernatremic patient hospitalized in the internal medicine ward and to enhance understanding of the role of antidiuretic hormone (ADH) secretion in the pathogenesis of hypernatremia. "
09/29/2023 - "However, NaX has also been detected in homeostatic effector neurons, such as vasopressin (VP) releasing magnocellular neurosecretory cells (MNCVP) which secrete VP (antidiuretic hormone) into the bloodstream in response to hypertonicity and hypernatremia. "
01/01/2021 - "With continually high Vasopressin infusion rates, her overall fluid balance became increasingly net positive, although her hypernatremia persisted. "
01/01/2017 - "The level of antidiuretic hormone (ADH) was measured in patients with hyperosmolar syndrome with hypernatremia. "
01/01/2017 - "The common features of the patients were extensive hypernatremia without any sensation of thirst and defects in vasopressin response to serum hypertonicity. "

11/01/2002 - "This study showed that acute hypernatremia induced by the infusion of 10% saline solution before graft procurement in a nonbrain-dead donor rat model did not lead to a deterioration of liver graft viability after OLT. "
01/01/2024 - "Given that the risk of hypernatremia is not important even in the neonates, we propose to use balanced isotonic IV-MFT in hospitalized children as it is better tolerated by the kidneys than 0.9% saline. "
07/17/2020 - "Normal saline comprised 76% of intravenous fluid volume administered prior to onset of moderate hypernatremia. "
11/01/2019 - "The use of either N/2 saline or normal saline in sick children at standard maintenance fluid rates is associated with low but comparable incidence of hypo or hypernatremia in first 24 h of hospitalization. "
01/01/2019 - "When patients lose access to a source of free water and are resuscitated with normal saline post operatively, they are at risk of developing life-threatening hypernatremia. "

03/01/2020 - "However, the large amounts of sodium bicarbonate sometimes required can be hazardous resulting in hypernatremia, hypervolemia, and hyperosmolality. "
08/01/2003 - "Because the infusion of sodium bicarbonate resulted in hypernatremia, the effect of hypernatremia was studied in an additional group that received hypertonic saline. "
01/01/1984 - "However, infusion of sodium bicarbonate did cause hyperosmolality and hypernatremia and a significant decrease in brain water content. "
09/01/1979 - "Usually, the patient is treated with massive amounts of intravenous sodium bicarbonate, which in itself carries many undesirable consequences such as fluid overload and hypernatremia. "
04/04/2014 - "We should keep in mind that acute hypernatremia and CPM can be associated with intravenous sodium bicarbonate therapy, and that CPM due to acute hypernatremia may be effectively treated with plasma exchange."

01/01/2010 - "Our results reveal that treatment of the patient with Desmopressin acetate relieved the adypsia, hypernatremia and hyperosmolality effectively. "
08/01/2023 - "Clinicians should be familiar of ODS with hypernatremia with transient DI in postpartum period, which is reversible and can be managed by desmopressin and fluid replacement."
12/01/2022 - "There is little information on the onset of hypernatremia after withdrawal of desmopressin. "
01/01/2022 - "Measurements of plasma osmolality and AVP concentration corroborate the pathophysiology and support the use of oral desmopressin in addition to dietary management to resolve the hypernatremia."
11/01/2021 - "Hypernatremia in our patient was initially refractory to fluid replacement but was eventually corrected with intravenous fluid and desmopressin. "

01/01/2004 - "We recommend hemodialysis is the best approach to correct severe hypernatremia."
10/01/2019 - "In our exploratory analysis, only hypernatremia was associated with mortality during hospitalization among patients with AKI or CKD undergoing acute hemodialysis."
10/01/2017 - "Iatrogenic hypernatremia in hemodialysis patients: A result of erroneous online conductivity monitor and conductivity meter reading."
01/01/2014 - "Patient was admitted to medicine intensive care unit and after inadequate response to suboptimal fluid repletion, hemodialysis was used to correct hypernatremia. "
01/01/2014 - "Hypernatremia: correction rate and hemodialysis."

03/07/1994 - "The study aimed at evaluating an incidence of hypo- and hypernatremia in the elderly and the results of therapy. "
12/01/2022 - "The proportion of neonates developing hypernatremia is significantly higher after using isotonic fluid for maintenance therapy. "
01/01/2022 - "In addition, our knowledge of the distribution of total body water influences us towards correcting hypernatremia as an appropriate therapy. "
01/01/2022 - "Early genetic testing can aid the diagnosis of unexplained recurrent neonatal hypernatremia and improve therapy and outcome."
05/01/2016 - "[Hypernatremia - Diagnostics and therapy]."

09/23/2013 - "Correction of hypernatremia using CVVHD is effective and safe. "
06/01/2020 - "This study aimed to evaluate the clinical effects of continuous veno-venous hemofiltration in the treatment of severely burned patients with acute hypernatremia. "
11/01/2023 - "Patients with severe hypernatremia, who have a significant short-term mortality rate, were shown to benefit from continuous venovenous hemofiltration (CVVH), which has been indicated to be successful. "
06/01/2020 - "Continuous veno-venous hemofiltration in the treatment of severely burned patients with acute hypernatremia: A retrospective study of 13 cases."
11/01/2015 - "Data on the management of acute hypernatremia using continuous venovenous hemofiltration (CVVH) are limited to anecdotes. "

07/01/2007 - "Initial rates of correction of hypernatremia were similar with intravenous and oral hypotonic fluid therapy. "
11/01/2006 - "Organic osmolytes accumulated during the adaptation to hypernatremia are slow to leave the cell during rehydration. "
05/01/1998 - "Initial fluid therapy should be given with care according to the rate of onset of hypernatremia, as deterioration of the animal's condition is a common sequela. "
01/01/1993 - "Hypernatremia persisted for at least 3 days despite the patients' rehydration. "
02/15/1992 - " Systematic surveillance of hypernatremia in the outpatient rehydration unit began in late 1984, and the trends in hypernatremia and analyses of key variables which affect its incidence in dehydrated children are reported. "

09/01/1999 - "With improved infant feeding practices and the advent of pediatric critical care medicine, the pattern of hypernatremia in children has likely changed. "
03/01/2018 - "Recent studies have noted that dysnatremia and hypernatremia are predictive of worsened outcomes in critical care and renal disease populations. "
12/01/2023 - "At birth, the infant was admitted to intensive care for severe hypernatremia (natremia 186 mg/dL). "
02/01/2022 - "Background Hypernatremia in the critical care setting is a major cause of morbidity and mortality. "
12/01/2020 - "In both cohorts, patients with hypernatremia had a higher mortality (Medical Information Mart for Intensive Care III: 20% vs 42%; p < 0.01 and electronic ICU: 6% vs 22%; p < 0.01), with hypernatremia increasing the risk of in-hospital mortality (Medical Information Mart for Intensive Care III: odds ratio, 1.15; 95% CI, 1.13-1.17 and electronic ICU: odds ratio, 1.11; 95% CI, 1.10-1.12) and over time using a Cox regression. "