Hydroxysteroids

Steroids in which one or more hydroxy groups have been substituted for hydrogen atoms either within the ring skeleton or on any of the side chains.

Networked: 13 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Poirier, Donald: 2 articles (07/2009 - 03/2003)
2.	Andersson, Charlotte: 1 article (08/2016)
3.	Auer, Paul L: 1 article (08/2016)
4.	Boehm, Bernhard: 1 article (08/2016)
5.	Buch, Stephan: 1 article (08/2016)
6.	Chan, Andrew T: 1 article (08/2016)
7.	Chasman, Daniel I: 1 article (08/2016)
8.	Chen, Constance: 1 article (08/2016)
9.	Choi, Hyon: 1 article (08/2016)
10.	Curhan, Gary: 1 article (08/2016)

Related Diseases

1.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 06/01/1997 - "In a previous study, we obtained evidence that A431 cells, derived from an epidermoid carcinoma of the vulva, are enriched in 17-HSD type 2, a membrane-bound isoform reactive with C18 and C19 17 beta-hydroxysteroids and 17-ketosteroids. "
2.	Endometrial Neoplasms (Endometrial Cancer) 07/01/2009 - "Thus, inhibitors of reductive 17beta-HSD isoforms are attractive to block the formation of hydroxysteroids that stimulate estrogeno-sensitive pathologies (breast, ovarian, and endometrium cancers) and androgeno-sensitive pathologies (prostate cancer, benign prostatic hyperplasia, acne, and hirsutism). " 03/01/2003 - "Thus, inhibitors of 17beta-HSDs are useful tools to elucidate the role of these enzymes in particular biological systems or for a therapeutic purpose, especially to block the formation of active hydroxysteroids that stimulate estrogeno-sensitive pathologies (breast, ovarian, and endometrium cancers) and androgeno-sensitive pathologies (prostate cancer, benign prostatic hyperplasia, acne, hirsutism, etc). "
3.	Prostatic Neoplasms (Prostate Cancer) 07/01/2009 - "Thus, inhibitors of reductive 17beta-HSD isoforms are attractive to block the formation of hydroxysteroids that stimulate estrogeno-sensitive pathologies (breast, ovarian, and endometrium cancers) and androgeno-sensitive pathologies (prostate cancer, benign prostatic hyperplasia, acne, and hirsutism). " 03/01/2003 - "Thus, inhibitors of 17beta-HSDs are useful tools to elucidate the role of these enzymes in particular biological systems or for a therapeutic purpose, especially to block the formation of active hydroxysteroids that stimulate estrogeno-sensitive pathologies (breast, ovarian, and endometrium cancers) and androgeno-sensitive pathologies (prostate cancer, benign prostatic hyperplasia, acne, hirsutism, etc). "
4.	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 07/01/2009 - "Thus, inhibitors of reductive 17beta-HSD isoforms are attractive to block the formation of hydroxysteroids that stimulate estrogeno-sensitive pathologies (breast, ovarian, and endometrium cancers) and androgeno-sensitive pathologies (prostate cancer, benign prostatic hyperplasia, acne, and hirsutism). " 03/01/2003 - "Thus, inhibitors of 17beta-HSDs are useful tools to elucidate the role of these enzymes in particular biological systems or for a therapeutic purpose, especially to block the formation of active hydroxysteroids that stimulate estrogeno-sensitive pathologies (breast, ovarian, and endometrium cancers) and androgeno-sensitive pathologies (prostate cancer, benign prostatic hyperplasia, acne, hirsutism, etc). "
5.	Hirsutism 07/01/2009 - "Thus, inhibitors of reductive 17beta-HSD isoforms are attractive to block the formation of hydroxysteroids that stimulate estrogeno-sensitive pathologies (breast, ovarian, and endometrium cancers) and androgeno-sensitive pathologies (prostate cancer, benign prostatic hyperplasia, acne, and hirsutism). " 03/01/2003 - "Thus, inhibitors of 17beta-HSDs are useful tools to elucidate the role of these enzymes in particular biological systems or for a therapeutic purpose, especially to block the formation of active hydroxysteroids that stimulate estrogeno-sensitive pathologies (breast, ovarian, and endometrium cancers) and androgeno-sensitive pathologies (prostate cancer, benign prostatic hyperplasia, acne, hirsutism, etc). "

Related Drugs and Biologics

1.	Protein Isoforms (Isoforms)
2.	17-Ketosteroids (17 Ketosteroids)
3.	Cholesterol
4.	Oxidoreductases (Dehydrogenase)
5.	Hydrocortisone (Cortisol)
6.	Enzymes
7.	Dexamethasone (Maxidex)
8.	Bile Acids and Salts (Bile Acids)
9.	Neurosteroids
10.	N 30