Hydroxyproline (4 Hydroxyproline)

12/01/2013 - "Our targeted gene therapy produced a significant anti-fibrosis effect, as shown by liver histology and significant reduction of hydroxyproline content. "
03/01/2003 - "However, the amount of histologically detectable fibrosis and the increase in liver hydroxyproline content was significantly greater in both models of fibrosis for treated controls than for treated ob/ob mice. "
12/01/2004 - "The histological changes of fibrosis, the hydroxyproline in the livers and HA were also improved in the treated rats. "
07/01/2014 - "Lung fibrosis was confirmed by a histologic study and an evaluation of the hydroxyproline content. "
12/15/2007 - "Lung fibrosis was assessed by histologic study and determination of hydroxyproline content. "

01/01/2014 - "Results revealed that the topical application of CvME (2.5% w/w) significantly accelerated the wound contraction rate (95.14%, 24 postoperative days), increased the hydroxyproline content (3.947 mg/100 mg tissue), and improved histopathology of wound tissue as compared to control groups. "
02/01/2007 - "The amount of hydroxyproline in the skin incisional wound with pFn was significantly greater than with an injection of albumin as control. "
11/01/2006 - "Compared with the control group, the endotoxin-only group had a significant reduction in both mean (SD) hydroxyproline levels and mean (SD) wound tensile strength (298.27 [17.66] vs 175.82 [18.73] g/cm2 and 7.16 [0.51] vs 4.01 [0.29] μg/mg wet tissue; both, P < 0.001). "
07/01/1989 - "Our previous animal experiments would suggest that delay of application of radiation to one week after wounding is accompanied by significant improvement in wound-breaking strength, new H3 hydroxyproline accumulation, and improved force-tension curves. "
01/01/2014 - "In vivo study confirmed the wound healing accelerating potential of IxME, as evidenced by faster wound contraction, higher hydroxyproline content, and improved histopathology of granulation tissue. "

04/01/2010 - "Treatment with GLE after the induction of liver fibrosis decreased the hepatic hydroxyproline content and improved liver histology. "
01/01/2014 - "Compared with N group, M group showed impaired liver function, liver fibrosis, increased hydroxyproline content, up-regulated expressions of α-SMA and TGF-β1, which have been reported to be pro-fibrogenic genes in vivo, and increased autophagy flux as indicated by the accumulation of LC3-II and degradation of p62. "
10/01/2013 - "Following four weeks of treatment, the rhHint1-treated rats exhibited significantly reduced liver fibrosis upon histopathological analysis and lower levels of hydroxyproline. "
03/01/2012 - "Liver fibrosis was assessed using Sirius red staining, hydroxyproline concentration and α-smooth muscle actin expression. "
12/01/2011 - "Hepatic cirrhosis leads to increased mortality and colonic anastomotic dehiscence, an increased distance between the mucosal edges of the anastomosis area, and a lower hydroxyproline concentration in the colonic anastomosis; therefore, these conditions are deleterious to healing."

01/01/2008 - "Efficacy of the treatment was assessed on the 28th-day by measuring stenosis index of the oesophagus and histopathological damage score, and biochemically by determining tissue hydroxyproline content. "
10/01/2006 - "Efficacy of the treatment was assessed by measuring the esophageal transit time, stenosis index, histopathologic damage score and biochemically by determining tissue hydroxyproline content, lipid peroxidation and antioxidant enzyme activities. "
01/01/2006 - "Efficacy of the treatment was assessed by measuring the stenosis index and histopathologic damage score and biochemically by determining tissue hydroxyproline content, lipid peroxidation and antioxidant enzyme levels. "
03/01/2005 - "Efficacy of the treatment was assessed in 28 days by measuring stenosis index and histopathologic damage score and by determining tissue hydroxyproline content. "
06/01/2004 - "Efficacy of the treatment was assessed on day 28 by measuring the stenosis index and histopathologic damage score and biochemically by determining tissue hydroxyproline content. "

07/01/2004 - "The inhibition of bone resorption was accompanied by a marked decrease in serum hydroxyproline. "
02/01/2004 - "The purpose of this study is to review the urine products of bone breakdown as markers of bone resorption and usefulness of urinary hydroxyproline. "
02/05/2002 - "B 678 (1996) 165] a urinary hydroxyproline-containing peptide has been preliminarily suggested as a possible alternative to hydroxyproline (HP) determination in bone resorption studies. "
09/01/1994 - "To monitor bone resorption serial measurements of urinary hydroxyproline and 45Ca excretion were made during the study. "
09/01/2007 - "Bone resorption markers, Urinary hydroxyproline excretion was significantly increased (p<0.001) in postmenopausal women. "