Hydroxy Acids

06/01/2010 - "The tolerability and efficacy of a cream formulated with a new mix of alpha-hydroxy acids (Hyseac AHA cream) in 248 patients with mild-moderate acne (comedonic, inflammatory, or mixed) have been investigated in a multicenter, non-randomized, open study by 10 dermatologists from different Italian areas during their routine practice. "
10/01/2015 - "Alpha hydroxy acids (AHA) have been recognized as commonly used therapy for acne. "
12/01/2014 - "Cosmeceuticals combining Rhealba(®) Oat plantlet extract and hydro-compensating actives, which are available with or without anti-comedogenic hydroxy acids, provide a balanced, multifaceted approach for acne patients. "
04/01/1996 - "[Alpha hydroxy acids in acne therapy]."
09/01/2010 - "Chemical peeling with both alpha and beta hydroxy acids has been used to improve acne scarring with pigmentation. "

01/01/2003 - "Alpha-hydroxy acids (AHAs) such as glycolic acid (GA) and lactic acid (LA) have been reported to be effective in treating pigmentary lesions such as melasma, solar lentigines, and postinflammatory hyperpigmentation. "

01/01/2003 - "Alpha-hydroxy acids (AHAs) such as glycolic acid (GA) and lactic acid (LA) have been reported to be effective in treating pigmentary lesions such as melasma, solar lentigines, and postinflammatory hyperpigmentation. "

01/01/1989 - "Cutaneous inflammation: effects of hydroxy acids and eicosanoid pathway inhibitors on vascular permeability."
01/01/1982 - "Since arachidonic acid metabolites play an important role in inflammation and have recently been suspected of modulating stimulus-secretion coupling, studies of the release of arachidonic acid from membrane phospholipids are important because all prostaglandins and hydroxy acids are derived from this initial step. "
11/15/1994 - "A unifying scheme for our findings includes the following enzymatic systems: (i) a PGH synthase-1/PG isomerase pathway responsible for constitutive generation of prostaglandins (e.g., PGE2) and maintenance of physiologic epithelial function; (ii) a PGH synthase-2/PG isomerase and synthase pathway capable of producing additional prostaglandins (e.g., excess PGE2 and/or PGF2 alpha and PGD2) especially after stimulation by growth factors and cytokines; and (iii) a family of arachidonate 12- and 15-lipoxygenases that may serve to generate hydroxy acids (e.g., 12- and 15-HETE) as mediators of basal epithelial function and that (after overexpression and oxidant activation) may also catalyze membrane peroxidation that contributes to epithelial damage during inflammation. "

05/15/2005 - "Intrahippocampal administration of the branched-chain alpha-hydroxy acids accumulating in maple syrup urine disease compromises rat performance in aversive and non-aversive behavioral tasks."
11/03/1976 - "Patients with maple syrup urine disease excrete not only alpha-keto and alpha-hydroxy acids but also six other metabolites which hitherto have been overlooked. "
03/01/1974 - "Branched-chain alpha-keto acids isolated as oxime derivatives: relationship to the corresponding hydroxy acids and amino acids in maple syrup urine disease."