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Horner Syndrome (Horner's Syndrome)

A syndrome associated with defective sympathetic innervation to one side of the face, including the eye. Clinical features include MIOSIS; mild BLEPHAROPTOSIS; and hemifacial ANHIDROSIS (decreased sweating)(see HYPOHIDROSIS). Lesions of the BRAIN STEM; cervical SPINAL CORD; first thoracic nerve root; apex of the LUNG; CAROTID ARTERY; CAVERNOUS SINUS; and apex of the ORBIT may cause this condition. (From Miller et al., Clinical Neuro-Ophthalmology, 4th ed, pp500-11)
Also Known As:
Horner's Syndrome; Syndrome, Horner's; Syndrome, Horner; Bernard Syndrome; Bernard's Syndrome; Claude Bernard-Horner Syndrome; Horner Syndrome, Acquired; Horner Syndrome, Central; Horner's Syndrome, Pupil; Ophthalmoplegia, Sympathetic Ocular; Ptosis Sympathetic; Sympathetic Ocular-Ophthalmoplegia; Acquired Horner Syndrome; Bernard Syndromes; Bernards Syndrome; Central Horner Syndrome; Claude Bernard Horner Syndrome; Horner Syndrome, Pupil; Horners Syndrome; Horners Syndrome, Pupil; Ocular Ophthalmoplegia, Sympathetic; Ocular Ophthalmoplegias, Sympathetic; Ocular-Ophthalmoplegia, Sympathetic; Ocular-Ophthalmoplegias, Sympathetic; Oculosympathetic Syndromes; Ophthalmoplegias, Sympathetic Ocular; Pupil Horner's Syndrome; Sympathetic Ocular Ophthalmoplegia; Sympathetic Ocular Ophthalmoplegias; Sympathetic Ocular-Ophthalmoplegias; Syndrome, Acquired Horner; Syndrome, Bernard; Syndrome, Bernard's; Syndrome, Central Horner; Syndrome, Claude Bernard-Horner; Syndrome, Oculosympathetic; Syndrome, Pupil Horner's; Syndromes, Bernard; Syndromes, Oculosympathetic; Miosis, Innervational Defect; Oculosympathetic Syndrome
Networked: 550 relevant articles (22 outcomes, 17 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Miosis
2. Blepharoptosis (Ptosis, Eyelid)
3. Enophthalmos
4. Pneumothorax
5. Paresis (Hemiparesis)

Experts

1. Brown, Sandra M: 3 articles (06/2005 - 08/2003)
2. Fay, Aaron: 2 articles (03/2018 - 10/2017)
3. Homer, Natalie: 2 articles (03/2018 - 10/2017)
4. Seemann, Joerg: 2 articles (03/2018 - 10/2017)
5. Spors, Birgit: 2 articles (03/2018 - 10/2017)
6. Baek, Jung Hwan: 2 articles (01/2018 - 08/2017)
7. Bischof, Georg: 2 articles (08/2013 - 12/2003)
8. Bosmans, Tim: 2 articles (03/2011 - 07/2009)
9. Gasthuys, Frank: 2 articles (03/2011 - 07/2009)
10. Marcilla, Miguel Gozalo: 2 articles (03/2011 - 07/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Horner Syndrome:
1. apraclonidine (Iopidine)FDA LinkGeneric
2. Cocaine (Cocaine HCl)IBA
3. Ophthalmic Solutions (Eye Drops)IBA
4. Phenylephrine (Neo-Synephrine)FDA LinkGeneric
5. Analgesics (Analgesic Drugs)IBA
12/01/2022 - "Secondary endpoints included analgesic efficiency (extent of early onset of pain relief as indicated by >50% improvement in Visual Analogue Scale (VAS) score at 300's post-procedure); occurrence of Horner's syndrome; extent of local anaesthetic distribution; and adverse events. "
10/01/2023 - "However, the aforementioned procedures have shown disadvantages such as catheter mobilization, which may cause injury to the artery, a weak analgesic effect, and Horner syndrome, as well as phrenic nerve paralysis. "
01/01/2021 - "The pain location and pain scores, analgesic medication, the cranial and caudal borders of dermatomes hypoesthetic for pin pricks, dysesthesia, urinary retention, Horner's syndrome, muscle strength, Karnofsky performance scale (KPS) score, patient satisfaction, hospital anxiety and distress score (HADS), and RAND 36 score were evaluated at 1 day; 1 and 6 weeks; and 3, 6, 9, 12 18, and 24 months after PCC, or until death if death occurred during the follow-up period. "
02/01/2017 - "Intraoperative analgesic and anesthetic requirement, postoperative numerical rating scale pain scores, additional analgesic consumption during the postoperative period, and incidence of complications related to thoracic paravertebral block (TPVB) like pleural puncture, pneumothorax, epidural spread, injection into the subarachnoid space, intravascular injection, and Horner's syndrome and rate of opioid related adverse reactions like nausea and vomiting, itching, constipation, and respiratory depression. "
6. Ganciclovir (Cytovene)FDA LinkGeneric
7. GlucocorticoidsIBA
8. Edrophonium (Tensilon)FDA LinkGeneric
9. CatecholaminesIBA
10. Local AnestheticsIBA

Therapies and Procedures

1. Sympathectomy (Sympathectomies)
2. Sclerotherapy
3. Nerve Block (Nerve Blocks)
4. Therapeutics
5. Lasers (Laser)