Hexosamines

09/01/2018 - "The dual treatment exhibited an enhanced wound area contraction and hexosamine content as compared to the other groups. "
01/27/2011 - "No significant difference between the hexosamine content of the wounds of animals treated with either Bulbine frutescens or Bulbine natalensis was found. "
09/01/2006 - "Even with respect to excision wounds, the fastest rate of epithelialization was seen with fraction I. Hexosamine estimation of granulation tissue obtained from excision wounds revealed an increase in the hexosamine content with fraction I compared with the control. "
05/01/1961 - "Water and hexosamine content in linear wounds, pedicled grafts, and autotransplants."
08/01/1954 - "Effects of growth, fasting, and trauma on the concentrations of connective tissue hexosamine and water."

04/29/2010 - "Many studies have been devoted to unveiling the molecular mechanisms in adipocytes in response to excess hexosamine flux-mediated insulin resistance. "
06/01/2004 - "Previously published studies suggest that an alteration in hexosamine flux induces a state of insulin resistance in muscle, liver, and other cell types. "
06/01/2011 - "The hexosamine biosynthetic pathway can mediate myocardial apoptosis in a rat model of diet-induced insulin resistance."
03/01/2011 - "We report here that hexosamine-induced insulin resistance is not additive with that induced by high fat feeding. "
03/01/2011 - "Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway."

04/01/2010 - "Using an in vitro model of embryo exposure to hyperglycemia, this study questioned if increased flux through the hexosamine signaling pathway (HSP), which results in increased embryonic O-linked glycosylation (O-GlcNAcylation), underlies the glucotoxic effects of hyperglycemia during early embryogenesis. "
04/01/2004 - "In the current study, the importance of hexosamine metabolites to hyperglycemia's effects on inotropic responses was examined in isolated perfused rat hearts. "
01/01/2020 - "The hexosamine biosynthesis pathway (HBP) is hypothesized to mediate many of the adverse effects of hyperglycemia. "
01/01/2013 - "Hyperglycemia activates several metabolic pathways, including the hexosamine biosynthetic pathway. "
11/01/2011 - "In particular, chronic hyperglycemia elicits PPP activation through the Keap1/Nrf2 system, which is induced by endoplasmic (ER) stress via an increase in hexosamine biosynthetic pathway flux. "

05/30/2017 - "Results of the present study depicted that each stress model significantly increased ulcer index, microvascular permeability and decreased hexosamine level, however, the maximum in the case of CRS-exposed rats. "
05/30/2017 - "This study evaluates ulcer index, hexosamine content, microvascular permeability, and gastric content in three acute stress models (cold-restraint, restraint, and water immersion restraint). "
04/01/1983 - "Further studies were performed regarding the progressive change of mucosal hexosamine content, gastric secretion and gastric emptying during the healing process of the ulcer. "
08/01/1989 - "These results suggest that [M] have a prophylactic effect on ulcerogenics, and an anti-ulcer effect by the increase and/or maintenance of gastric mucosal blood flow and hexosamine, but further investigations are required to understand the mechanism involved."
04/01/1983 - "It was found that the increase of hexosamine plays an important role in the healing of the ulcer and that a durable fall in hexosamine content was related to the remarkable exacerbation of ulcer induced by either ASP or IND. "

01/01/2016 - "As feeding of the hexosamine pathway metabolite glucosamine to aged mice increased their life expectancy we tested whether supplementation of this aminosugar may also protect mice from acute kidney injury after renal ischemia and reperfusion. "
04/01/2008 - "Hexosamine biosynthesis and protein O-glycosylation: the first line of defense against stress, ischemia, and trauma."
02/01/2006 - "Increased hexosamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia."
09/01/2007 - "We have previously shown that preischemic treatment with glucosamine improved cardiac functional recovery following ischemia-reperfusion, and this was mediated, at least in part, via enhanced flux through the hexosamine biosynthesis pathway and subsequently elevated O-linked N-acetylglucosamine (O-GlcNAc) protein levels. "