Hemorrhoids

Swollen veins in the lower part of the RECTUM or ANUS. Hemorrhoids can be inside the anus (internal), under the skin around the anus (external), or protruding from inside to outside of the anus. People with hemorrhoids may or may not exhibit symptoms which include bleeding, itching, and pain.

Also Known As:

Networked: 735 relevant articles (69 outcomes, 110 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Hemorrhage
2.	Hemorrhoids
3.	Pain (Aches)
4.	Prolapse
5.	Postoperative Pain

Experts

1.	Gupta, P J: 8 articles (12/2011 - 10/2003)
2.	Gupta, Pravin J: 6 articles (01/2008 - 07/2002)
3.	Akkol, Esra Küpeli: 5 articles (01/2014 - 12/2008)
4.	Hachiro, Yoshikazu: 4 articles (05/2014 - 07/2007)
5.	Kunimoto, Masao: 4 articles (05/2014 - 07/2007)
6.	Abe, Tatsuya: 4 articles (05/2014 - 07/2007)
7.	Kalaskar, S: 4 articles (12/2011 - 02/2008)
8.	Gaj, F: 3 articles (01/2015 - 05/2006)
9.	Gu, Jing-Kai: 3 articles (10/2014 - 01/2012)
10.	Wu, Xiu-Jun: 3 articles (10/2014 - 01/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hemorrhoids:

1.	Diosmin (Daflon)IBA 04/01/2014 - "Both Roidosanal(®) and Daflon(®) 500 mg were equally effective in resolving signs and symptoms of hemorrhoids. " 06/01/1994 - "The author reports the results of a double-blind, placebo-controlled trial of the efficacy of Daflon 500 mg in the treatment of acute and chronic symptoms of hemorrhoids. " 12/01/2002 - "Efficacy of Daflon in the treatment of hemorrhoids." 04/01/2014 - "In this pilot, active controlled, open-labeled multicentre study, 73 patients with proctoscopy proven hemorrhoids (Grade I to III) were randomly assigned to receive either Roidosanal(®) (Gr R; n = 37) or Daflon(®) 500 mg (Gr D; n = 36), for 15 days, at three centers in India. " 12/01/2010 - "(Vitaceae) to Daflon (Servier) and placebo in the treatment of acute hemorrhoids."
2.	Suppositories (Vaginal Suppositories)IBA 04/01/1978 - "The treatment of hemorrhoids should be started by instructing the patient on anal hygiene, to be followed only then by symptomatic application of creams or suppositories. " 01/01/1972 - "An assessment of anesthetic-steroid suppositories: a controlled trial following rubber-band ligation of hemorrhoids." 12/01/2011 - "To alleviate symptoms caused by hemorrhoids, oral treatments, such as fiber, suppositories and Sitz baths have been applied to patients. " 04/01/1986 - "[Belladonna poisoning after the use of hemorrhoid suppositories]." 09/01/1997 - "Physician examiners diagnosed significantly more hemorrhoids among those using primarily suppositories and enemas to manage their bowels (P < 0.05) and more constipation among persons with paraplegia (P < 0.05) and those using digital stimulation, manual evacuation, or increased abdominal pressure in their bowel programs. "
3.	TabletsIBA 05/01/2003 - "Zhiranxiao tablets are also effective in the treatment of internal hemorrhoid hemorrhage." 05/01/2005 - "Fuhuang Tablets are effective and safe in treating internal hemorrhoid hemorrhage." 05/01/2003 - "[Therapeutical effect of Zhiranxiao tablets on internal hemorrhoid hemorrhage: a clinical observation in 569 cases]." 05/01/2005 - "To assess the efficacy of Fuhuang Tablets in treating internal hemorrhoid hemorrhage and discussing the design and quality control of clinical trials of traditional Chinese medicine. " 05/01/2003 - "The treatment group consisted of 596 patients with internal hemorrhoid hemorrhage who received oral Zhiranxiao tablets in a course of 6 d for treatment, and another 60 such patients were given a different preparation from traditional Chinese medicine, Zhining tablets, to serve as the control group. "
4.	LaxativesIBA 05/01/1985 - "High-fibre diets and bulk laxatives are effective in relieving the symptoms of hemorrhoids, easing defecation and regulating bowel habit and can be used liberally. " 08/01/1992 - "Hemorrhoids are usually relieved with use of bulk laxatives or stool softeners; if this fails, coagulation or rubber band ligation may be effective. "
5.	proctofoam-HCIBA 02/01/2011 - "Proctofoam-HC is a combination of a corticosteroid and a local anaesthetic that is proven effective for the treatment of hemorrhoids. " 07/01/2009 - "Proctofoam-HC appears to provide effective treatment of hemorrhoids in late pregnancy." 02/01/2011 - "Proctofoam-HC is safe to use in the treatment of hemorrhoids in late pregnancy." 07/01/2009 - "The effectiveness of Proctofoam-HC for treatment of hemorrhoids in late pregnancy." 02/01/2011 - "The fetal safety of hydrocortisone-pramoxine (Proctofoam-HC) for the treatment of hemorrhoids in late pregnancy."
6.	Hydrocortisone (Cortisol)FDA LinkGeneric 02/01/2015 - "HPS has to a certain extent significantly reduced the symptoms of hemorrhoids in pregnancy and improved the well-being of pregnant women in comparison with topical treatment with hydrocortisone cream. " 02/01/2015 - "This study was to evaluate the efficacy between drug treatment with Procort (topical hydrocortisone cream 1%) and mechanical treatment with a Hai's Perianal Support (HPS) toilet seat device in managing symptomatic hemorrhoids during the third trimester of pregnancy. " 02/01/2015 - "Comparing topical hydrocortisone cream with Hai's Perianal Support in managing symptomatic hemorrhoids in pregnancy: a preliminary trial." 09/01/1986 - "Hemorrhoids are a common medical problem that usually can be managed conservatively with dietary changes, stool softeners, and local hydrocortisone creams. " 06/21/2015 - "Recombinant streptokinase vs hydrocortisone suppositories in acute hemorrhoids: A randomized controlled trial."
7.	Calcium DobesilateIBA 10/01/2001 - "A randomized, double-blind, controlled study was conducted to investigate the efficacy of oral calcium dobesilate therapy in treating acute attacks of internal hemorrhoids. " 10/01/2001 - "Twenty-nine well-documented adult patients with first- or second-degree internal hemorrhoids were treated with calcium dobesilate for two weeks, while16 patients received only a high-fiber diet to serve as control. " 10/01/1995 - "[Effectiveness and innocuousness of the association of calcium dobesilate, dexamethasone acetate and lidocaine versus prednisolone capronate with dibucaine clorohydrate in the treatment of hemorrhoids-]."
8.	Plant Preparations (Preparation, Plant)IBA 04/01/2014 - "Efficacy of a standardized herbal preparation (Roidosanal(®)) in the treatment of hemorrhoids: A randomized, controlled, open-label multicentre study." 04/01/2014 - "This study compares the efficacy of two herbal preparations, Daflon(®) 500 mg and Roidosanal(®), in ameliorating the signs and symptoms associated with hemorrhoids. "
9.	Nifedipine (Adalat)FDA LinkGeneric 03/01/2001 - "The aim was to test the efficacy of local application of nifedipine ointment in healing acute thrombosed external hemorrhoids. " 03/01/2001 - "Our study clearly demonstrates that the use of topical nifedipine, which at present is for treatment of cardiovascular disorders, is a reliable new option in the conservative treatment of thrombosed external hemorrhoids." 03/01/2001 - "Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine." 03/01/2001 - "Results obtained were as follows: complete relief of pain in 43 patients (86 percent) of the nifedipine-treated group as opposed to 24 patients (50 percent) of the control group after 7 days of therapy (P < 0.01); oral analgesics were used by 4 patients (8 percent) in the nifedipine-treated group as opposed to 26 patients (54.1 percent) of the control group after 7 days of therapy (P < 0.01); and resolution of acute thrombosed external hemorrhoids was achieved after 14 days of therapy in 46 patients (92 percent) of the nifedipine-treated group, as opposed to 22 patients (45.8 percent) of the control group (P < 0.01). "
10.	HesperidinIBA 05/01/1997 - "In the short term, micronized diosmin 90% and hesperidin 10% is safe, acceptable, and effective in the treatment of hemorrhoids of pregnancy." 05/01/1997 - "In an open study on hospital outpatients, we studied therapy with micronized diosmin 90% and hesperidin 10% for a median of 8 weeks before delivery and 4 weeks after delivery, in 50 women with acute hemorrhoids. "

Therapies and Procedures

1.	Ligation 08/01/1979 - "Elastic ligature of internal hemorrhoid nodules was done ambulatorily with good results and no important complications. " 02/01/2011 - "Doppler-guided hemorrhoidal artery ligation is a minimally invasive technique for the treatment of symptomatic hemorrhoids that has been applied successfully for grade II and III hemorrhoids but is less effective for grade IV hemorrhoids. " 12/01/1986 - "We have then reported about the good results obtained with 162 patients suffering from stage 2, 3 and 4 hemorrhoids, by using band ligation. " 10/01/2013 - "Rubber band ligation is an effective treatment for hemorrhoids. " 10/01/2011 - "Doppler-guided hemorrhoid artery ligation seems to be a safe and effective treatment option for all grades of hemorrhoidal disease. "
2.	Sclerotherapy 06/01/2011 - "ALTA sclerotherapy is a simple and safe treatment for symptomatic hemorrhoids, with few complications." 04/01/2002 - "In conclusion, the approach of banding or sclerotherapy of hemorrhoids in SCI patients is safe and effective. " 10/01/1993 - "The aim of our study was to assess the medium to long-term outcome following single session large dose injection sclerotherapy for symptomatic hemorrhoids. " 02/10/1993 - "Where conservative treatment measures are justified and surgical intervention can be foregone, new studies on the sclerotherapy of hemorrhoids have led to a change in therapeutic objectives. " 06/01/1971 - "[Experimental study of sclerotherapy of hemorrhoids]."
3.	Diathermy 06/01/2011 - "This randomized prospective controlled trial confirms, according to other large trials in literature , the benefits of the LigaSure™ hemorrhoidectomy over conventional diathermy when a large tissue demolition is required, supporting the use of this device as treatment of choice in IV degree hemorrhoids, even if the procedure is more expensive than conventional operation." 06/01/2011 - "This randomized study is Fifty-two patients with IV-degree hemorrhoids were randomly assigned to two different surgical treatments (conventional diathermy vs. LigaSure™ hemorrhoidectomy). " 06/01/2010 - "This randomized study compared results obtained with the Ferguson's technique for the treatment of hemorrhoids performed with a radiofrequency (RF) scalpel and traditional diathermy. " 01/01/2009 - "Randomized controlled trials comparing hemorroidectomy using the Ligasure-technique with conventional diathermy techniques for symptomatic hemorrhoids in adult patients were included. " 03/01/2004 - "Prospective, randomized trial comparing diathermy excision and diathermy coagulation for symptomatic, prolapsed hemorrhoids."
4.	Lasers (Laser) 12/01/2014 - "A comparison trial between hemorrhoid laser procedure or open surgical hemorrhoidectomy was made. " 12/01/2014 - "Laser Hemorrhoidoplasty Procedure vs Open Surgical Hemorrhoidectomy: a Trial Comparing 2 Treatments for Hemorrhoids of Third and Fourth Degree." 04/01/1998 - "Further studies using pulse laser are warranted as a possible nonexcisional interstitial treatment for hemorrhoids." 11/01/1989 - "The laser treatment of hemorrhoids: results of a study on 1816 patients." 06/01/2011 - "Significantly higher quality of life was seen in the hemorrhoid laser procedure group (P = .002). "
5.	Light Coagulation 03/01/2009 - "The results of quality of life estimation in the patients are presented, in whom infrared photocoagulation was applied for chronic internal hemorrhoids, including in 141 (58%) of them--performed, according to the standard method (control group) and in 102 (42%)--according to the elaborated method of selective infrared photocoagulation of distal branches of a. " 03/01/2009 - "[Quality of life in patients with chronic internal hemorrhoids treated with infrared photocoagulation]." 07/01/1998 - "[Infrared photocoagulation in the treatment of hemorrhoids]." 09/01/1993 - "Infrared photocoagulation is a new ambulatory therapy for 1st, 2nd and 3rd degree internal hemorrhoids. " 09/01/1993 - "[The outpatient management of internal hemorrhoids by infrared photocoagulation]."