Hemorrhagic Septicemia (Haemorrhagic Septicemia)

Any of several bacterial diseases, usually caused by PASTEURELLA MULTOCIDA, marked by the presence of hemorrhagic areas in the subcutaneous tissues, serous membranes, muscles, lymph glands, and throughout the internal organs. The diseases primarily affect animals and rarely humans.

Also Known As:

Networked: 120 relevant articles (13 outcomes, 13 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Infection
2.	Foot-and-Mouth Disease
3.	Necrosis
4.	Edema
5.	Wound Infection (Wound Infections)

Experts

1.	Estepa, A: 7 articles (10/2014 - 12/2008)
2.	Coll, J M: 7 articles (10/2014 - 12/2008)
3.	Tafalla, C: 7 articles (08/2011 - 07/2006)
4.	Parton, Roger: 5 articles (06/2012 - 07/2002)
5.	Estepa, Amparo: 4 articles (11/2015 - 01/2010)
6.	Coll, Julio: 4 articles (11/2015 - 01/2010)
7.	Zamri-Saad, M: 4 articles (11/2015 - 10/2006)
8.	Gomez-Casado, E: 4 articles (10/2014 - 03/2011)
9.	Encinas, P: 4 articles (12/2012 - 03/2009)
10.	Cuesta, A: 4 articles (08/2011 - 12/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hemorrhagic Septicemia:

1.	2,5-dichloro-4-bromophenol (B 2)IBA 12/01/2007 - "Safety and protective efficacy of intramuscular vaccination with a live aroA derivative of Pasteurella multocida B:2 against experimental hemorrhagic septicemia in calves." 08/18/2012 - "The efficacy of an intranasal haemorrhagic septicaemia vaccine containing live gdhA derivative Pasteurella multocida B:2 was tested in buffaloes in Sabah. " 08/18/2012 - "Efficacy of intranasal vaccination of field buffaloes against haemorrhagic septicaemia with a live gdhA derivative Pasteurella multocida B:2." 01/01/2011 - "Efficacy of an inactivated recombinant vaccine encoding a fimbrial protein of Pasteurella multocida B:2 against hemorrhagic septicemia in goats." 03/01/2005 - "Efficacy of vaccination of calves against hemorrhagic septicemia with a live aroA derivative of Pasteurella multocida B:2 by two different routes of administration."
2.	aluminum sulfate (alum)IBA 03/01/1995 - "Effect of storage on the prevalent alum-precipitated hemorrhagic septicaemia vaccine in Pakistan and preparation of a more efficient oil adjuvant vaccine using dense culture of Pasteurella multocida Roberts type 1 on an improved culture medium." 02/03/2007 - "Efficacy of haemorrhagic septicaemia alum-precipitated vaccine." 03/01/1995 - "Significantly drastic effects of storage on the potency of the alum-precipitated haemorrhagic septicaemia (APHS) vaccine are reported. " 05/01/1965 - "Haemorrhagic septicaemia alum precipitated vaccines."
3.	Bacterial VaccinesIBA 10/15/1997 - "The experiment demonstrated that the experimental oil adjuvant vaccine was superior to broth bacterin in providing protection against experimental haemorrhagic septicaemia in young buffalo calves beyond 250 days." 01/01/1951 - "Laboratory studies on the immunizing value of hemorrhagic septicemia bacterin and blackleg bacterin." 10/15/1997 - "The other groups of animals, vaccinated with broth bacterin or used as control (non-vaccinated), developed symptoms of haemorrhagic septicaemia. "
4.	Proteins (Proteins, Gene)IBA 09/01/2012 - "Vibrio anguillarum is part of the natural flora in the aquatic habitat, but under certain circumstances it can cause terminal hemorrhagic septicemia in marine fish due to the action of virulence-associated proteins. " 01/01/2010 - "This work describes the differential infected versus non-infected expression of proteins and immune-related transcripts in fins and organs of zebrafish Danio rerio shortly after infection-by-immersion with viral haemorrhagic septicemia virus (VHSV). " 04/01/1975 - "Purified infectious hematopoietic necrosis (IHN) virus and the virus of haemorrhagic septicaemia (VHS) (Egtved virus) each contain five structural proteins which were designated L, G, N, M-1, and M-2. " 10/01/2009 - "Identification of immunogenic proteins associated with protection against haemorrhagic septicaemia after vaccination of calves with a live-attenuated aroA derivative of Pasteurella multocida B:2." 09/01/2000 - "Water-soluble proteins from Aeromonas sobria, a causative agent of bacterial hemorrhagic septicemia of fishes, were separated into six fractions by gel chromatography on Sephadex G-100. "
5.	DNA (Deoxyribonucleic Acid)IBA 03/01/2002 - "It was recently reported that DNA vaccination of rainbow trout fingerlings against viral hemorrhagic septicaemia virus (VHSV) induced protection within 8 days after intramuscular injection of plasmid DNA. " 10/01/2010 - "DNA vaccination has proved a very effective method for controlling viral infections in fish, especially those provoked by rhabdovirus such as viral hemorrhagic septicaemia virus (VHSV). " 04/26/2010 - "The pIPNV-PP vaccine was expressed at the injection site and up-regulated MHC Ialpha, MHC IIalpha, type-I interferon (IFN), Mx, CD4 and CD8alpha gene expression in the muscle, head kidney or spleen, although to a much lower extent than the up-regulations observed in response to an effective DNA vaccine against viral hemorrhagic septicaemia virus (VHSV). " 08/01/2007 - "calcarifer vaccinated with a single dose of DNA plasmid encoding the major outer membrane protein shows moderate protection against acute haemorrhagic septicaemia and mortality by V. anguillarum experimental infection." 03/18/2009 - "A plasmid DNA encoding the viral hemorrhagic septicaemia virus (VHSV)-G glycoprotein under the control of 5' sequences (enhancer/promoter sequence plus both non-coding 1st exon and 1st intron sequences) from carp beta-actin gene (pAE6-G(VHSV)) was compared to the vaccine plasmid usually described the gene expression is regulated by the human cytomegalovirus (CMV) immediate-early promoter (pMCV1.4-G(VHSV)). "
6.	Membrane Proteins (Integral Membrane Proteins)IBA 10/01/2002 - "Comparative analysis of the outer membrane protein profiles of isolates of the Pasteurella multocida (B:2) associated with haemorrhagic septicaemia." 08/01/2007 - "calcarifer vaccinated with a single dose of DNA plasmid encoding the major outer membrane protein shows moderate protection against acute haemorrhagic septicaemia and mortality by V. anguillarum experimental infection." 12/01/2013 - "Pasteurella multocida serogroup B:2, a causative agent of haemorrhagic septicaemia (HS) in cattle and buffalo especially in tropical regions of Asian and African countries, is known to possess several outer membrane proteins (OMPs) as immunogenic antigens. " 07/01/1996 - "Binding of host iron-binding proteins and expression of iron-regulated membrane proteins by different serotypes of Pasteurella multocida causing haemorrhagic septicaemia."
7.	DNA VaccinesIBA 12/15/2012 - "The work is relevant to fish vaccination, since DNA vaccines use eukaryotic expression plasmids controlled by the human cytomegalovirus (CMV) promoter to be effective against novirhabdoviruses, such as viral haemorrhagic septicemia virus (VHSV), one of the most devastating fish viral European diseases. "
8.	Tissue ExtractsIBA 06/01/1992 - "Inclusion of high-ionic strength buffers helped us to develop a sandwich ELISA to detect hemorrhagic septicemia virus (HSV) in cell culture and infected trout tissue extracts. "
9.	TabletsIBA 03/01/1951 - "A case of haemorrhagic septicaemia treated successfully with sulphapyridine (M&B 693) tablets."
10.	SulfapyridineFDA Link 03/01/1951 - "A case of haemorrhagic septicaemia treated successfully with sulphapyridine (M&B 693) tablets."

Therapies and Procedures

1.	Intramuscular Injections 03/01/2002 - "It was recently reported that DNA vaccination of rainbow trout fingerlings against viral hemorrhagic septicaemia virus (VHSV) induced protection within 8 days after intramuscular injection of plasmid DNA. "