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Crimean Hemorrhagic Fever

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A severe, often fatal disease in humans caused by the Crimean-Congo hemorrhagic fever virus (HEMORRHAGIC FEVER VIRUS, CRIMEAN-CONGO).

Also Known As:

Hemorrhagic Fever, Crimean; Infection, Congo Virus; Congo Virus Infections; Crimean Hemorrhagic Fevers; Fever, Crimean Hemorrhagic; Fevers, Crimean Hemorrhagic; Hemorrhagic Fevers, Crimean; Infections, Congo Virus; Congo Virus Infection

Networked: 14 relevant articles (1 outcomes, 1 trials/studies)

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Disease Context: Research Results

Virus Diseases: 1820
- RNA Virus Infections: 103
  - Viral Hemorrhagic Fevers: 57
    - Crimean Hemorrhagic Fever: 14
  - Bunyaviridae Infections: 12
    - Crimean Hemorrhagic Fever: 14
- Arbovirus Infections: 39
  - Tick-Borne Diseases: 158
    - Crimean Hemorrhagic Fever: 14

Related Diseases

1.	Yellow Fever
2.	Infection
3.	Hemorrhagic Fever with Renal Syndrome (HFRS)
4.	Dengue (Dengue Fever)

Experts

1.	Vasilenko, N F: 1 article (01/2014)
2.	Malyshev, B S: 1 article (01/2014)
3.	Volynkina, A S: 1 article (01/2014)
4.	Iashina, L N: 1 article (01/2014)
5.	Netesova, N A: 1 article (01/2014)
6.	Sologub, T V: 1 article (01/2012)
7.	Kovalenko, A L: 1 article (01/2012)
8.	Galimzianov, K M: 1 article (01/2012)
9.	Lokteva, O M: 1 article (01/2012)
10.	Romantsov, M G: 1 article (01/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Crimean Hemorrhagic Fever:

1.	TabletsIBA 01/01/2012 - "The study aimed at estimating the pharmacotherapeutic efficacy of medications possessed of antiviral activity, such as ribavirin, cycloferon solution and tablets, in 410 patients with Crimean hemorrhagic fever: The early beginning of therapy (days 1-4 after the onset of the disease) with these drugs reduced the number of severe cases and manifestations of hemorrhagic syndrome. "
2.	Ribavirin (Virazole)FDA LinkGeneric 01/01/2012 - "The study aimed at estimating the pharmacotherapeutic efficacy of medications possessed of antiviral activity, such as ribavirin, cycloferon solution and tablets, in 410 patients with Crimean hemorrhagic fever: The early beginning of therapy (days 1-4 after the onset of the disease) with these drugs reduced the number of severe cases and manifestations of hemorrhagic syndrome. "
3.	10-carboxymethyl-9-acridanoneIBA 01/01/2012 - "The study aimed at estimating the pharmacotherapeutic efficacy of medications possessed of antiviral activity, such as ribavirin, cycloferon solution and tablets, in 410 patients with Crimean hemorrhagic fever: The early beginning of therapy (days 1-4 after the onset of the disease) with these drugs reduced the number of severe cases and manifestations of hemorrhagic syndrome. "
4.	Antiviral Agents (Antivirals)IBA 01/01/2012 - "[Efficacy of antiviral agents in the treatment of Crimean hemorrhagic fever]."
5.	AntigensIBA 01/01/1989 - "Paper presents the results of a successful use of a solid-phase immunoassay for indication of the antigen of hemorrhagic fever-Crimean--Congo virus in lays and half-fed female-ticks Hyalomma marginatum marginatum Koch (1795) collected in endemic area, which adds to our knowledge of this disease focus activity." 11/01/1984 - "[Detection of the antigens of the virus of Congo-Crimean hemorrhagic fever by solid-phase immunoenzyme analysis and by the indirect hemagglutination reaction]." 03/01/1972 - "Sequential titration of infective virus and complement-fixing antigen in brain and liver of suckling mice infected with the following virus strains-Dugbe (a new arbovirus), Congo (related to Crimean hemorrhagic fever virus), yellow fever, dengue 1 and dengue 2-showed a progressive increase in titer after infection. "
6.	AntibodiesIBA 09/01/1977 - "[Titration of the antibodies to the Crimean hemorrhagic fever virus in a drop of the cell suspension from infected tissue cultures by means of indirect immunofluorescence]." 05/26/1974 - "[Crimean hemorrhagic fever antibodies in Hungary]." 11/01/1996 - "In the period June-November 1995, 292 sera from 159 patients and 80 healthy persons from Kosovo and Metohia were tested for the presence of antibodies against the causative agents of Crimean hemorrhagic fever (CHF) and hemorrhagic fever with renal syndrome (HFRS). "
7.	Monoclonal AntibodiesIBA 06/01/1989 - "A series of hybridomas producing monoclonal antibodies to Crimean hemorrhagic fever virus was obtained and their cultural properties were characterized. " 06/01/1989 - "[Hybridomas producing monoclonal antibodies to Crimean hemorrhagic fever virus]." 03/01/1989 - "Twelve lines of hybridomas secreting monoclonal antibodies (MCA) have been generated by fusion of spleen lymphocytes of BALB/c mice immunized with crude Crimean hemorrhagic fever virus (CHF). " 03/01/1989 - "[Characteristics of the monoclonal antibodies induced by the Crimean hemorrhagic fever virus]."
8.	Neutralizing AntibodiesIBA 07/01/1980 - "Close relationship of Crimean hemorrhagic fever-Congo (CHF-C) virus strains by neutralizing antibody assays."
9.	Trichlorfon (Metrifonate)IBA 12/01/1967 - "[Use of chlorophos with a prolongator in the antitick treatment of cattle in a focus of Crimean hemorrhagic fever]."
10.	Carbaryl (Sevin)IBA 07/01/1968 - "[Acaricidal effect of various phospho-organic preparations and sevin on the vector of Crimean hemorrhagic fever, the tick Hyalomma plumbeum plumbeum]."