Vitamin K Deficiency Bleeding

07/01/1992 - "One hundred term exclusively breast fed babies weighing more than 2.5 kg were evaluated to determine the efficacy of various modes and doses of Vitamin K to prevent hemorrhagic disease of newborn (HDN). "
01/01/2016 - "An interprofessional approach to education can be effective in increasing acceptance of vitamin K prophylaxis and decreasing the incidence of vitamin K deficiency bleeding. "
07/01/2010 - "The formation of the British Paediatric Surveillance Unit in the 1980s has allowed a series of prospective population studies of Vitamin K deficiency bleeding (VKDB) in the United Kingdom (UK) and Ireland which, together with contemporaneous surveys of practices of vitamin K prophylaxis, have greatly improved our understanding of the condition and informed practices of prophylaxis. "
12/01/2015 - "Uptake of vitamin K is associated with ethnicity and also factors in the infant that might imply a perceived protection against vitamin K deficiency bleeding. "
02/01/1997 - "Prevention of vitamin K deficiency bleeding: efficacy of different multiple oral dose schedules of vitamin K."

07/01/1999 - "There is increasing evidence, however, that oral phytomenadione prophylaxis is less effective for the prevention of late vitamin K deficiency bleeding (VKDB) than intramuscular prophylaxis. "
01/01/2013 - "Vitamin K deficiency bleeding after NICE guidance and withdrawal of Konakion Neonatal: British Paediatric Surveillance Unit study, 2006-2008."
11/17/2023 - "All newborns need extra phylloquinone (vitamin K1; K1) to prevent vitamin K deficiency bleeding (VKDB). "
09/25/2015 - "All newborns require phylloquinone after birth to prevent vitamin K deficiency bleeding. "
03/01/2013 - "Prevention of vitamin K deficiency bleeding with three oral mixed micellar phylloquinone doses: results of a 6-year (2005-2011) surveillance in Switzerland."

05/01/2017 - "• Some case reports showed PCC seemed to be effective for infants and children with coagulation factor deficiency, but evidence about the effectiveness of PCC to reverse serious Vitamin K Deficiency Bleeding is limited. "
11/15/2013 - "Vitamin K deficiency bleeding (VKDB) is a coagulopathy that develops in infants who do not have sufficient vitamin K stores to support production of clotting factors. "
09/01/2013 - "Vitamin K deficiency bleeding (VKDB) disorder is an uncommon entity, which occurs due to inadequate activity of vitamin K-dependant coagulation factors. "
06/01/2014 - "Vitamin K deficiency bleeding is an acquired coagulopathy in newborn infants because of accumulation of inactive vitamin K-dependent coagulation factors, which leads to an increased bleeding tendency. "

01/01/1957 - "[Analytic study of Quick's time and heparin tolerance test in hemorrhagic disease of newborn; role of hyperfibrinolysis]."

01/01/2020 - "Analysis revealed that 32 cases were most likely caused by acquired prothrombin complex deficiency (APCD) and 30 of these APCD cases were strongly suspected to be manifestations of vitamin K deficiency bleeding (VKDB). "
01/01/2022 - "Laboratory results showed anemia, prolonged prothrombin and activated partial thromboplastin time, supporting the diagnosis of vitamin K deficiency bleeding. "
12/01/2015 - "Prothrombin Complex Concentrate for Intracerebral Hemorrhage Secondary to Vitamin K Deficiency Bleeding in a 6-Week-Old Child."

12/15/2019 - "Preventive Role of Vitamin K in Antibiotic-induced Vitamin K Deficiency Bleeding in Neonates: Author's Reply."
12/15/2019 - "Preventive Role of Vitamin K in Antibiotic-induced Vitamin K Deficiency Bleeding in Neonates."

03/01/2015 - "It's not just a vitamin: comment on "Rise in late onset vitamin K deficiency bleeding in young infants because of omission or refusal of prophylaxis at birth" by Schulte and colleagues."

12/05/2005 - "During 2001, a questionnaire was sent to the chief pediatrician in charge to the all 33 nurseries of the region asking the methods used during 2000 as prevention of ophthalmia neonatorum, early and late hemorrhagic disease of newborn, umbilical cord care and recommendations of vitamin D administration. "

04/15/1954 - "[Prevention of hemorrhagic disease of newborn with oral plasmatic thrombin]."

01/01/1995 - "Some examples of the influence of age on hemostasis are: (1) the diagnosis of some congenital factor deficiencies, based on plasma levels, can be difficult due to physiologically low values; (2) despite very low levels of many inhibitors of hemostasis, thrombotic complications are rare; (3) the interaction of anti-coagulants and thrombolytic agents is profoundly influenced by the relative immaturity of hemostasis at birth; and (4) in contrast to the risk of thrombosis, healthy infants are at risk for vitamin K deficiency bleeding due to poor transport of vitamin K across the placenta and plasma concentrations of the vitamin K dependent proteins of less than 50% of adults values. "

01/01/2002 - "Prophylaxis and therapy of vitamin K deficiency bleeding are discussed."
06/01/2007 - "Vitamin K deficiency bleeding after missed prophylaxis: rapid synergistic effect of vitamin K therapy on hemostasis."

01/01/2017 - "Objectives Vitamin K deficiency bleeding (VKDB) in infants is a coagulopathy preventable with a single dose of injectable vitamin K at birth. "
06/01/2012 - "Use of oral vitamin K for prevention of late vitamin k deficiency bleeding in neonates when injectable vitamin K is not available."
06/01/2012 - "To evaluate the literature describing use of oral vitamin K(1) (phytonadione) to prevent late vitamin K deficiency bleeding (VKDB) in neonates when injectable vitamin K preparations are not available. "

07/01/2019 - "Additionally, infants with intracranial vitamin K deficiency bleeding were identified using the Dutch Pediatric Intensive Care Evaluation registry. "
06/01/2011 - "To determine the incidence of late intracranial vitamin K deficiency bleeding (VKDB) in The Netherlands using the Dutch Pediatric Intensive Care Evaluation (PICE) registry. "

08/01/2013 - "Vitamin K deficiency bleeding and early infant male circumcision in Africa."