Hemolysis

11/15/2011 - "In a "humanized" sickle cell model mouse, forced TR2/TR4 expression increased HbF abundance from 7.6% of total hemoglobin to 18.6%, accompanied by increased hematocrit from 23% to 34% and reticulocyte reduction from 61% to 18%, indicating a significant reduction in hemolysis. "
09/01/1995 - "In-vitro hemolysis testing showed a significant reduction in average plasma hemoglobin release, from 19.4 mg/dl to 1.8 mg/dl, when air was removed during blood aspiration. "
07/01/1995 - "During in vitro hemolysis testing, the removal of air by the jet driven aspirator showed a significant reduction in hemolysis: plasma hemoglobin levels increased 19.4 mg/dl without air removal and only 1.8 mg/dl with air removal (p < 0.001). "
01/01/1990 - "In addition, some 80 variants without overt hemolysis have given positive results with in vitro hemoglobin instability tests. "
07/01/2015 - "Moreover, the duration between sampling and hemolysis assay was a source of heterogeneity among studies, as were the initial free hemoglobin levels in the various experiments. "

01/01/2014 - "Indeed, in the last decad the anti-C5 monoclonal antibody has proven effective for the treatment of PNH, resulting in a sustained control of complement-mediated intravascular hemolysis, with a remarkable clinical benefit. "
11/01/2012 - "In the last decade the anti-C5 monoclonal antibody has been proven effective for the treatment of PNH, resulting in a sustained control of complement-mediated intravascular hemolysis, with a remarkable clinical benefit. "
03/01/2002 - "Transfer of prostasomal CD59 to CD59-deficient red blood cells results in protection against complement-mediated hemolysis."
03/01/2015 - "This study investigated whether Stx2 induces hemolysis and whether complement is involved in the hemolytic process. "
11/01/2014 - "The objective of this study was to develop a simple rat model of complement-mediated acute intravascular hemolysis. "

09/01/1977 - "Hemolysis was significantly greater in RBC from vitamin E-deficient rats. "
03/01/1975 - "Vitamin E caused a moderate fall in porphyrin excretion, however, there was no significant improvement in light tolerance and tendency to hemolysis. "
08/01/1995 - "Vitamin E was effective in treating the intravascular hemolysis."
12/25/1988 - "Vitamin E in the erythrocyte membranes was also effective in suppressing the hemolysis. "
04/01/2011 - "Several clinical trials have indicated that vitamin E might be used therapeutically as a potential erythropoietic agent for decreasing the premature erythrocyte hemolysis by reducing the fragility of erythrocytes. "

01/01/2008 - "Eculizumab is very effective in the treatment of intravascular hemolysis and all its sequelae, which include most of the symptoms and complications of PNH. "
03/27/2014 - "The anti-C5 antibody eculizumab has proven clinically effective, but uncontrolled C3 activation due to CD55 absence may result in opsonization of erythrocytes, possibly leading to clinically meaningful extravascular hemolysis. "
12/01/2013 - "The results of studies demonstrate that treatment with eculizumab alters the natural history of PNH by virtually eradicating thromboembolic complications, inhibiting of intravascular hemolysis and reducing or eliminating transfusion requirements. "
09/01/2015 - "Management of the classical form of PNH has been dramatically revolutionized by the development of eculizumab, which brings benefits in terms of hemolysis, quality of life, renal function, thrombotic risk, and life expectancy. "
07/01/2015 - "In vitro hemolysis due to non-mutant and mutant C5 was completely blocked by N19-8, a monoclonal antibody that binds to a different site on C5 than does eculizumab. "

11/01/2005 - "The purpose of this study was to describe the abdominal imaging features associated with HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome, a complication of pregnancy. "
07/01/2004 - "The aim of this study was to evaluate retrospectively 10 women with the syndrome of hemolysis, elevated liver enzymes, low platelets (HELLP)--age of patients, quality of antepartum medical care, clinical, biochemical parameters, treatment, course and duration of pregnancies, way of delivery, and puerperium. "
01/01/2004 - "This study was set up to determine the long-term (5 or more years) renal function after HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome during pregnancy and to answer the question whether long-term renal follow-up is necessary. "
06/01/2003 - "The purpose of this study was to describe subsequent pregnancy outcome in women with a history of hemolysis, elevated liver enzymes, and low platelet count syndrome for which delivery occurred at < or = 28 weeks of gestation during the index pregnancy. "
05/01/2001 - "Our aim was to study the utility of umbilical artery Doppler velocimetry in the management of women with the HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome. "

12/01/2008 - "In presence of AAPH, hemolysis was significantly greater in HYPO (732.45+/-40% min) and lower in HYPER (578.97+/-15% min) as compared to ISO (608.30+/-42% min). "
01/01/2015 - "However, it provided protection against 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH)-induced oxidative hemolysis which declined by 10.2% (p<0.001). "
10/01/2014 - "The present study assessed the antioxidant activity and protective ability of Clitoria ternatea flower petal extract (CTE) against in vitro 2,2'-azobis-2-methyl-propanimidamide dihydrochloride (AAPH)-induced hemolysis and oxidative damage of canine erythrocytes. "
05/01/2005 - "In this study, we demonstrated that Chuling in vitro protects red blood cells from 2,2-azo-bis(2-amidinopropane)dihydrochloride (AAPH)-induced hemolysis. "
04/01/2005 - "In this study, we demonstrated that ST in vitro protects red blood cells from 2,2-azo-bis (2-amidinopropane) dihydrochloride (AAPH)-induced hemolysis. "

02/01/2010 - "The neonatal hemolysis was relieved obviously and bilirubin was reduced gradually after exchange transfusion. "
02/15/2014 - "Package inserts suggest that hemolysis decreases direct bilirubin measurements, but no published studies have adequately described the extent of interference. "
01/01/2011 - "Our study revealed a significant increase in the mean values of unconjucated bilirubin (P < 0.05) while running with soft insoles indicating the occurrence of hemolysis in this group of athletes. "
09/01/2009 - "The purpose of this study was to evaluate a CE method for detecting bilirubin and albumin-bound bilirubin in rat serum and to measure potential interference by hemolysis and specific test compounds. "
10/01/2004 - "Nineteen term neonates without hemolysis whose serum bilirubin levels were above 20 mg/dl and 27 healthy term newborns with bilirubin levels <13 mg/dl were included in the study. "

12/01/1996 - "A significant reduction in serum haptoglobin at two hours and an increase in serum LDH at 24 hours indicated that hemolysis was the likely cause of the initial fall in hematocrit. "
01/01/2011 - "The aim of the study was to evaluate whether serum haptoglobin could be measured to assess hemolysis in recently transfused patients. "
11/01/2004 - "The aim of the study was to check if a slight and non visible hemolysis to naked eye such as that induced by blood coagulation could interfere in the immunonephelometric measurement of haptoglobin, and if this interference was dependent on the protein phenotype. "
01/01/1983 - "No abnormal in vivo hemolysis occurred as judged from posttransfusion haptoglobin consumption studies. "
01/01/2015 - "Serum haptoglobin (Hp) is a reliable marker for hemolysis regardless the inflammatory state. "

06/29/1994 - "Hemolytic peptides have proven to be very useful in studying the mechanism of hemolysis and the permeability properties of red blood cells. "
11/01/2013 - "The results of MTT and hemolysis assay indicated that the analog peptides displayed an improved anticancer activity and showed an overall optimized therapeutic index. "
06/15/2006 - "Relative to the free peptides, the product shows a 10-fold improvement in IC(50) without provoking more severe hemolysis of red blood cells. "
01/01/2010 - "CoilA and CoilB peptides, both representing coiled-coil regions of the translocator protein EspA, and CoilD peptide, corresponding to a coiled-coil region of the needle protein EscF, were effective in inhibiting the TTSS dependent hemolysis of red blood cells by the EPEC E2348/69 strain. "
01/01/2015 - "Based on blood hemolysis studies, a little hemolytic effect was showed in the case of both peptides even when applied at high concentrations. "

08/01/1984 - "This method of assaying hemolysis in a liquid grown medium has proven effective in determining the hemolytic properties of strains which appeared negative or questionable on blood agar as well as strains which in virulence tests were negative. "
03/01/2014 - "We noticed that incorporation of selected herbal extracts in blood agar medium showed significant reduction in hemolysis (MIC 300μl/plate), indicating inhibition of SLO. "
10/01/2002 - "The Lancefield system of serogrouping the streptococci by the expression of beta-hemolysis on blood agar plates is still very useful for the identification of streptococci for patient management. "
03/01/1965 - "In addition, hemolysis was suppressed in old cultures in which viability was diminished, and was eliminated when colonies were removed from the agar surface by micromanipulation. "
06/01/2011 - "The aim of the study was to assess the reliability of human blood agar media (HuBA) in identifying Streptococcus pyogenes by hemolysis analysis. "

11/01/2003 - "Splenectomy was effective for the amelioration of hemolysis. "
11/01/1975 - "In this regard, splenectomy was followed by an improvement in erythrocyte survival, although evidence of continuing hemolysis was obtained."
07/01/1989 - "Signs of increased hemolysis, erythrocyte morphology, osmotic fragility, autohemolysis, heat and mechanical stability of the erythrocyte membrane, intracellular cation concentration and studies of other family members, are indispensable prerequisites for classification, prognosis, and indication of therapeutic efforts, especially splenectomy."
03/01/1985 - "Ferrokinetic studies still appreciate with better insight the amount of ineffective erythropoiesis or hemolysis and remains therefore of great value when splenectomy is discussed."
11/06/2014 - "Thrombotic events were associated with Hb levels ≤6 g/dL at onset, intravascular hemolysis, and previous splenectomy. "

02/01/2012 - "This observational study assessed the efficacy of a standardized pretransplant isoagglutinin reduction strategy incorporating donor-type secretor plasma infusions with or without plasma exchange to prevent PCI-associated hemolysis and PRCA in major or bidirectional ABO-mismatched peripheral blood HPCT. "
05/01/1993 - "Treatment with plasma exchange was effective in halting the hemolysis, but renal function failed to improve. "
01/01/1988 - "In this study we report our experience of two patients with severe life-threatening hemolysis and in whom plasma exchange was not feasible due to red blood cell autoagglutination in the extracorporeal circuit. "
09/01/2015 - "Therapeutic Plasma Exchange for Refractory Hemolysis After Brown Recluse Spider (Loxosceles reclusa) Envenomation."
11/01/2014 - "Successful use of plasma exchange for profound hemolysis in a child with loxoscelism."

12/01/1990 - "Hemolysis was improved by chemotherapy. "
08/10/2015 - "Drug induced hemolysis is a frequent complication associated with chemotherapy. "
03/01/2015 - "The cause of significant hemolysis was identified as chemotherapy and prosthetic valve in 48.1% of specimens. "
01/01/2014 - "One patient had minor undiagnosed hemolysis after the previous chemotherapy cycle and two of our three patients had minor allergic signs just before the hemolysis. "
07/01/2003 - "Current pharmacotherapy focuses on increasing HbF in order to reduce hemolysis and help prevent acute vaso-occlusive events. "

11/01/1989 - "[A study on hemolysis in hemodialysis patients]."
12/01/2015 - "Gradual deterioration of red blood cells (RBCs) due to mechanical stress (chronic hemolysis) is unavoidable during treatments that involve extracorporeal blood circulation, such as hemodialysis (HD). "
07/01/2015 - "Re-evaluation of Pre-pump Arterial Pressure to Avoid Inadequate Dialysis and Hemolysis: Importance of Prepump Arterial Pressure Monitoring in Hemodialysis Patients."
03/01/2014 - "Three years after ceasing treatment, the patient presented no signs of hemolysis, but required chronic hemodialysis. "
01/01/2014 - "Hemolysis as a rare but potentially life-threatening complication of hemodialysis: a case report."

01/01/1996 - "Plasmapheresis helped abolish the hemolysis. "
02/01/1993 - "This study is an investigation into the effects of module design on hemolysis levels during the filtration enhancement of plasmapheresis using pulsed blood flow. "
07/01/2013 - "Plasmapheresis can be used to treat G6PD deficient patients with severe hemolysis due to unidentified trigger agent. "
07/01/2013 - "As the patient developed severe hemolysis and the trigger agent of hemolysis was unknown, two cycles of plasmapheresis were performed with the aim to remove unknown causative agent. "
07/01/2013 - "We describe one young patient with severe hemolysis treated with two cycles of plasmapheresis which proved to be an effective tool in the treatment. "