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Sickle Hemoglobin

An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.
Also Known As:
Hemoglobin, Sickle; Deoxygenated Sickle Hemoglobin; Deoxyhemoglobin S; Hemoglobin SS; Hemoglobin, Deoxygenated Sickle; SS, Hemoglobin; Sickle Hemoglobin, Deoxygenated; Hemoglobin S
Networked: 1024 relevant articles (23 outcomes, 63 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Gladwin, Mark T: 19 articles (01/2021 - 09/2002)
2. Safo, Martin K: 14 articles (07/2021 - 09/2008)
3. Abdulmalik, Osheiza: 12 articles (01/2022 - 09/2008)
4. Steinberg, Martin H: 12 articles (01/2022 - 06/2002)
5. Kato, Gregory J: 10 articles (01/2021 - 01/2006)
6. Gordeuk, Victor R: 9 articles (01/2022 - 01/2008)
7. Abboud, Miguel R: 7 articles (01/2022 - 01/2006)
8. Buchanan, George R: 7 articles (09/2014 - 10/2003)
9. Eaton, William A: 6 articles (11/2022 - 02/2005)
10. Gupta, Kalpna: 6 articles (05/2022 - 07/2010)

Related Diseases

1. Sickle Cell Anemia (Hemoglobin S Disease)
2. Malaria
3. Thalassemia
4. Sickle Cell Trait
5. Stroke (Strokes)

Related Drugs and Biologics

1. Fetal Hemoglobin (Hemoglobin F)
2. Hemoglobin C
3. beta-Globins (beta Globin)
4. Hydroxyurea (Hydrea)
5. Hemoglobin A
6. Blood Group Antigens (Blood Groups)
7. glucose-6-phosphate dehydrogenase A-
8. Foscarnet
9. Ganciclovir (Cytovene)
10. Primaquine

Related Therapies and Procedures

1. Therapeutics
2. Transplantation
3. Blood Transfusion (Blood Transfusions)
4. Extracorporeal Membrane Oxygenation
5. Artificial Respiration (Mechanical Ventilation)