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Heme Oxygenase (Decyclizing) (Heme Oxygenase)

A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt.
Also Known As:
Heme Oxygenase; Oxygenase, Haem; Oxygenase, Heme; Haem Oxygenase; Heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
Networked: 1069 relevant articles (46 outcomes, 122 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ndisang, Joseph Fomusi: 27 articles (01/2016 - 05/2003)
2. Abraham, Nader G: 22 articles (01/2022 - 01/2003)
3. Vanella, Luca: 17 articles (05/2022 - 05/2008)
4. Jadhav, Ashok: 17 articles (01/2014 - 01/2007)
5. Sorrenti, Valeria: 10 articles (05/2022 - 06/2013)
6. Stec, David E: 10 articles (01/2022 - 04/2005)
7. Barbagallo, Ignazio: 10 articles (01/2021 - 06/2013)
8. Wong, Ronald J: 10 articles (01/2021 - 10/2002)
9. Stevenson, David K: 9 articles (01/2021 - 10/2002)
10. Li Volti, Giovanni: 9 articles (05/2020 - 04/2005)

Related Diseases

1. Inflammation (Inflammations)
2. Hypertension (High Blood Pressure)
3. Sepsis (Septicemia)
4. Ischemia
5. Atherosclerosis

Related Drugs and Biologics

1. Carbon Monoxide
2. Enzymes
3. tin protoporphyrin IX
4. Nitric Oxide Synthase (NO Synthase)
5. Hemin (Panhematin)
6. Bilirubin
7. Heme (Haem)
8. Endotoxins
9. Cytokines
10. Metalloporphyrins

Related Therapies and Procedures

1. Phototherapy (Light Therapy)
2. Therapeutics
3. Transplantation
4. Spinal Injections
5. Ligation