Artificial Heart (Artificial Hearts)

A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed)

Also Known As:

Networked: 574 relevant articles (19 outcomes, 25 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Shah, Keyur B: 11 articles (07/2020 - 05/2012)
2.	Kasirajan, Vigneshwar: 10 articles (07/2020 - 01/2010)
3.	Slepian, Marvin J: 10 articles (01/2020 - 08/2004)
4.	Frazier, O H: 7 articles (06/2020 - 11/2000)
5.	Arabia, Francisco A: 7 articles (07/2017 - 08/2003)
6.	Koerfer, Reiner: 7 articles (07/2016 - 08/2005)
7.	Tenderich, Gero: 7 articles (07/2016 - 08/2005)
8.	Morshuis, Michiel: 6 articles (01/2022 - 03/2006)
9.	Tang, Daniel G: 6 articles (07/2020 - 05/2012)
10.	Morales, David L S: 6 articles (03/2020 - 01/2012)

Related Diseases

1.	Heart Failure 12/25/2020 - "As an effective treatment of heart failure, artificial heart is gradually used in clinical treatment. " 09/01/2014 - "The total artificial heart (TAH) is effective for bridging patients with biventricular heart failure (BiVHF) to transplantation. " 06/01/2014 - "Currently, ventricular assist device (VAD) or total artificial heart (TAH) mechanical support provides an effective treatment of unstable patients with advanced heart failure. " 01/01/2015 - "Heart transplantation still remains the gold standard therapy for end-stage heart failure, although several other approaches have emerged, such as biventricular pacing, left ventricular assist devices (LVADs) and total artificial heart. " 08/26/2004 - "The purpose was to assess the safety and efficacy of the CardioWest Total Artificial Heart in transplant-eligible patients at risk for imminent death from irreversible biventricular cardiac failure. "
2.	Thrombosis (Thrombus) 07/01/1990 - "General design goals, including improved fit for human application, improved reliability, and elimination of thrombus formation, were identified as improvements over the clinically used Jarvik-7 artificial heart, previously developed at the Institute for Biomedical Engineering, University of Utah. " 09/01/1975 - "These studies indicate that platelets are extremely sensitive to shear stress and raise the possibility that thrombus formation and/or accelerated platelet turnover in patients with rheumatic valvular disease or who possess artificial heart valves or other cardiac prosthetic devices could result from the effects of this physical force on circulating platelets." 02/16/2023 - "Recent progress in high-molecular compounds opened new horizons in overcoming major drawbacks of mechanical and tissue heart valves (dysfunction and failure, tissue degradation, calcification, high immunogenic potential, and high risk of thrombosis), providing new insights into the development of an ideal artificial heart valve. " 01/01/2023 - "We describe two total artificial heart patients with sudden obstruction to the filling of the right side due to fixing of the atrioventricular valve in a closed position due to a thrombus. " 01/01/2023 - "Reversal of Total Artificial Heart Mechanical Valve Thrombosis Using Catheter-Directed Thrombolysis."
3.	Atrial Fibrillation 11/01/2013 - "We included 235 outpatients of the Institute of Cardiology (Warsaw), mean age 69.3, 46.9% women, receiving AC for artificial heart valves and/or atrial fibrillation. " 09/01/1999 - "The presence of atrial fibrillation and the use of oral anticoagulation prior to heart valve surgery support the indication for the insertion of a mechanical artificial heart valve. " 09/01/1999 - "Atrial fibrillation is often seen in patients with artificial heart valves. " 09/01/1999 - "Insertion of a mechanical artificial heart valve is an absolute indication for the use of lifelong oral anticoagulation, irrespective the presence or absence of atrial fibrillation. " 01/01/1997 - "In 50 patients (30F, 20M), aged 47 +/- 8 who underwent artificial heart valve implantation, the transient ST segment elevation (uST) of at least 0.1 mV on ECG immediately after electrical cardioversion (KE) of atrial fibrillation (MP) was evaluated. "
4.	Hemolysis 01/01/1984 - "Improved red cell survival in patients with chronic subclinical haemolysis due to artificial heart valve. " 07/01/2001 - "[Experimental study of the relationship of the level of blood hemolysis and the design of artificial heart valves]." 09/01/1999 - "The total artificial heart (TAH) being developed by these authors successfully completed hydrodynamic and hemolysis studies followed by two acute implantations. " 01/01/1963 - "Hemolysis studies on three types of artificial heart pump valves." 01/01/2022 - "Downsizing of a Pulsatile Total Artificial Heart-The Effect on Hemolysis."
5.	Cardiovascular Diseases (Cardiovascular Disease) 01/01/1997 - "The products of modern technology including computerized tomography, computer enhanced digital angiography, magnetic resonance imaging, ultrasonic-cardiography, positron emission tomography, single photon emission computerized tomography, percutaneous transluminal coronary angioplasty and other techniques, laser, artificial pacemaker, artificial heart etc. have greatly improved the capacity of diagnosis and therapy of cardiovascular diseases. " 01/01/2021 - "Due to an increasing number of cardiovascular diseases, artificial heart valves and blood vessels have been developed. " 11/01/1985 - "Past estimates of the potential usage of artificial hearts have been reviewed in the context of advances in medical care and in the prevention of cardiovascular disease. " 01/01/1988 - "The objectives of these studies were to reduce thromboembolic complications in arterial cardiovascular diseases (prevention of myocardial infarction in unstable angina, secondary prevention of acute myocardial infarction, and increased patency of aortocoronary bypass grafts) and to reduce platelet deposition on artificial surfaces (artificial heart valves and hemodialysis shunts). " 11/01/2022 - "Recently, implantable biomaterials and devices, especially minimally invasive interventional ones, such as vascular stents, artificial heart valves, bioprosthetic cardiac occluders, artificial graft cardiac patches, atrial shunts, and injectable hydrogels against heart failure, have become the most effective means in the treatment of cardiovascular diseases. "

Related Drugs and Biologics

1.	Warfarin (Coumadin)
2.	Anticoagulants
3.	Aspirin (Acetylsalicylic Acid)
4.	Clopidogrel (Plavix)
5.	Lupus Coagulation Inhibitor (Lupus Anticoagulant)
6.	Dipyridamole (Persantine)
7.	Smoke
8.	Platelet Aggregation Inhibitors (Antiplatelet Drugs)
9.	Plasticizers
10.	Interferons

Related Therapies and Procedures

1.	Therapeutics
2.	Heart-Assist Devices
3.	Heart Transplantation (Grafting, Heart)
4.	Transplantation
5.	Renal Dialysis (Hemodialysis)