Heart Diseases (Heart Disease)

01/01/2018 - "The intervention improved best clinical practice in 118 patients consenting to assessment (of 831 eligible patients): repeat cholesterol test (+75.4%, 95% CI 66.9-82.3); family history of heart disease assessed (+35.6%, 95% CI 27.0-44.2); diagnosis of secondary causes (+7.7%, 95% CI 4.1-13.9), examining clinical features (+6.0%, 95% CI 2.9-11.7). "
02/01/2006 - " For the best protection against clogged arteries and heart disease, average cholesterol no longer makes the grade--lower is better."
12/01/1995 - "A systematic examination of the evidence on the relationship between serum cholesterol and ischaemic heart disease shows conclusively that serum cholesterol reduction in populations with high rates of heart disease is an effective and safe method of reducing ischaemic heart disease rates. "
06/10/2014 - "To examine whether a cholesterol-lowering diet is more effective in reducing ischaemic heart disease and lowering cholesterol than no dietary intervention in children and adults with familial hypercholesterolaemia. "
01/20/2010 - "To examine whether a cholesterol-lowering diet is more effective in reducing ischaemic heart disease and lowering cholesterol than no dietary intervention in children and adults with familial hypercholesterolaemia. "

10/01/2014 - "However, on the basis of the evidence currently available, we support the current guidelines recommending antiarrhythmic drugs as a first-line treatment in most patients with AF except younger patients with symptomatic paroxysmal AF with no evidence of structural heart disease, given the risk of fatal complications associated with the ablation procedure. "
01/01/1991 - "Although there is good evidence in many forms of heart disease that complex VEBs indicate a high risk of death, treatment of asymptomatic VEBs with antiarrhythmic drugs has not been shown to improve survival and may be hazardous. "
10/01/2000 - "EAT in children without underlying heart disease can be effectively treated using antiarrhythmic drugs. "
09/01/2013 - "This is an ideal tool for assessing the electrophysiologic profile of heart disease patients with implants and to assess the efficacy of various treatments (anti-arrhythmic drugs, ablation procedures). "
08/01/2011 - "An improved understanding of how anti-arrhythmic drugs affect the electrophysiological mechanisms of AF initiation and maintenance, in the setting of the different cardiac diseases that predispose to AF, is therefore required. "

11/01/1996 - "The combination of the two drug tests, electrophysiologic study and Holter monitoring, is a useful method for the prediction of the long-term efficacy of amiodarone in patients with sustained VT and underlying heart disease. "
01/01/2005 - "Amiodarone was more effective for preventing recurrence in patients with poorer left ventricular function and underlying heart disease."
01/01/1992 - "The present article reviews the therapeutic efficacy of class III antiarrhythmic agents, particularly amiodarone, in patients with atrial and ventricular arrhythmias in the setting of different cardiac disorders. "
03/01/2014 - "Amiodarone (AMI) is a low water-solubility drug, which is very useful in the treatment of severe cardiac disease. "
11/01/1986 - "Thus, in patients with frequent VPCs and no underlying heart disease, oral intake of T3 during amiodarone treatment is safe and does not abolish the antiarrhythmic efficacy of amiodarone, despite a shortening of the QTc.(ABSTRACT TRUNCATED AT 250 WORDS)"

01/01/2013 - "Although a number of experimental studies have demonstrated that oxidative stress plays a major role in heart ischaemia/reperfusion pathophysiology, controlled clinical trials have failed to prove the efficacy of antioxidants in acute or long-term treatments of ischaemic heart disease. "
06/24/2009 - "Oxidative stress plays a major role in the pathophysiology of cardiac disorders, but the experimental data on the protective effects of exogenous antioxidants are controversial. "
09/29/2011 - "The ability of antioxidants to inhibit injury has raised the possibility of new therapeutic treatment for diabetic heart diseases. "
11/01/2002 - "The ability of antioxidants to inhibit these apoptotic pathways has raised the possibility of newer therapeutic treatment for various heart diseases."
05/14/2004 - "The recognition of the critical involvement of oxidative and electrophilic stress in cardiac disorders has led to extensive investigation of the protective effects of exogenous antioxidants on cardiac injury. "

05/01/1998 - "Women lose their relative protection against coronory heart disease at menopause because of changed lipid profile due to oestrogen deficiency. "
01/01/2019 - "We aimed at evaluating the six-month efficacy of an intensive lipid-lowering intervention, coordinated by nurses and implemented after hospital discharge, in patients hospitalized for an ischaemic heart disease event. "
01/01/2021 - "While traditionally heart disease, family history, lipid profile, and tobacco use have all been associated with increased risk of neurological disease, numerous studies now show that the influence of poverty may be just as strong a risk factor. "
12/01/2020 - "Plasma lipid levels during ACS: Association with 20-year mortality: The ABC-5 Study on Heart Disease."
08/30/2020 - "The aim of the present study was to detect potential gender-specific associations between some common CD36 single nucleotide polymorphisms (SNPs) and the lipid profile, as well as the susceptibility to premature multi-vessel coronary artery heart disease (CHD) in the Han population of Northern China. "

05/11/2005 - "Ischaemic heart disease, smoking habit, and treatment with statins were associated with a significantly greater percent of resistance (p=0.049, 0.009, and 0.043, respectively). "
04/01/2013 - "Statins are the current standard treatment for the majority of these patients, and have been shown to be effective in reducing the incidence of cardiovascular heart disease in patients with FH. "
05/29/1996 - "Statin is effective against heart disease]."
01/01/2021 - "However, trial populations used criteria that often excluded those with atherosclerotic heart disease (ASHD), in whom statins have the greatest benefit, and included outcome composites with high rates of nonatherosclerotic CV events that may not be modified by statins. "
04/15/2016 - "Moreover, fly studies have demonstrated the potential of exercise and statins to treat age-related cardiac disease. "

05/06/2021 - "Traditional biomarkers are very useful as diagnostic and prognostic tools in the cardiovascular field; however, their application is usually limited to overt cardiac disease. "
06/01/2009 - "Plasma BNP level is a very useful biochemical marker predictive of future hospitalization in community-dwelling independent elderly people without apparent heart diseases."
01/01/2022 - "Fortunately, a host of emerging cardiovascular biomarkers characterizing and quantifying ischaemic heart disease have shown great promise in both laboratory settings and clinical trials. "
01/01/2021 - "Hematological biomarkers may help to identify increased mortality risk of acute heart disease patients, receiving RBC transfusions in an internal medicine department."
01/01/2019 - "To meet this requirement, a precise investigation on the efficacy of multicomponent drugs against HF using the signature biomarkers-oriented approach was developed and applied to a conventional drug for cardiac disease, YiXinShu (YXS). "

01/01/2023 - "Study groups were matched for baseline demographics, atopic comorbidities, heart diseases and utilization of β-blockers, and angiotensin-converting enzyme inhibitors. "
07/13/2021 - "The clinical importance of high ACE gene variant-positive prevalence in some breeds requires further study because the highest prevalences were found in breeds that are predisposed to heart disease and therefore may be treated with ACE-inhibitors."
04/01/1990 - "Further studies are required to establish the clinical importance of cardioprotection by ACE-inhibitors in ischaemic heart disease."
04/01/1990 - "However, these cardioprotective effects have not yet been shown in patients with ischaemic heart disease, although some studies indicate that ACE-inhibitors are also able to cause anti-ischaemic effects in patients. "
09/01/2021 - "Retrospective evaluation of a dose-dependent effect of angiotensin-converting enzyme inhibitors on long-term outcome in dogs with cardiac disease."

01/01/2020 - "Direct oral anticoagulants (DOACs) have been proven to be safe and effective in patients with acquired heart disease. "
01/01/2002 - "During the last few years the efficacy of oral anticoagulant treatment in the prevention of thromboembolic complications among patients with cardiac diseases has been well established. "
01/01/1996 - "This new technique has many fields of application: investigation of asymptomatic emboli in patients with emboligenic heart disease, efficacy of antiaggregant, anticoagulant or surgical treatments."
08/01/2021 - "This study will evaluate a potentially valuable alternative of oral anticoagulant prophylactic use in children with cardiac diseases."
03/01/2019 - "Use of direct oral anticoagulant in ischaemic heart disease: the COMPASS study."

08/01/2009 - "This study demonstrated that LDL-C measures can remain controlled in most patients discharged from a cardiac disease management program."
01/01/2022 - "Predictive value of LDL/HDL ratio in coronary atherosclerotic heart disease."
01/01/2022 - "However, higher levels of LDL-C were not significantly associated with residual risk of coronary atherosclerotic heart disease. "
01/01/2020 - "LDL subfraction linked to vascular ageing and heart disease in SLE."
01/01/2020 - "This meta-analysis suggested that flaxseed supplementation improves serum TC, TG, and LDL-C, which could delay the progression of heart disease. "

11/01/2022 - "We focused on the recent advancement of genome editing in hPSCs, which dramatically improved the efficiency of the cell-based mechanism study and therapy for cardiac diseases."
08/15/2018 - "The patterns most likely reflect big lifestyle changes, improved socioeconomic status, less targeted heart disease prevention programs, and advance in medical therapies."
01/01/2012 - "Mortality from ischemic cardiac disease in adults has been dramatically reduced by the development of novel therapies for inhibiting platelet function. "
07/01/2010 - "The diagnosis and management of canine heart disease could be facilitated by a highly sensitive and specific laboratory test that predicts risk of morbidity and mortality, is helpful in directing therapy, easy to perform, inexpensive, and widely available. "
05/01/2009 - "Commonalities and differences at the molecular level will identify critical pathways of pathogenesis, and response to therapy, or both: indeed, gene expression profiling holds tremendous promise for classifying clinical phenotypes, developing prognostic predictors and, most importantly, providing novel unbiased insights into the mechanisms underlying heart disease and, eventually, novel causative genes. "

02/01/2017 - "Heart transplantation is considered the best treatment modality for advanced heart disease. "
11/01/2007 - "Despite being accepted as the best treatment for end-stage heart diseases, the long-term benefit of heart transplantation in children remains a matter of controversial debate. "
02/01/1999 - "With a survival rate of 70% at 3 years, cardiac transplantation is the best treatment for end-stage heart disease. "
10/01/1993 - "Our data demonstrate that after heart transplantation prognosis of end-stage cardiac disease is highly improved either for life expectancy and for quality of life. "
01/01/1991 - "Orthotopic heart transplantation continues to be a highly successful therapy for end-stage cardiac disease. "

03/17/2020 - "Catheter ablation of non-reentrant, commonly termed "idiopathic" ventricular arrhythmias (VA) is highly effective in patients without structural heart disease (SHD). "
06/01/1992 - "Based on these findings, we conclude that RF catheter ablation of VT in patients without structural heart disease was highly effective and safe. "
11/01/2015 - "Considering that ~10-12% of patients have the first symptomatic recurrences only 1-2 years after ablation and others in the next years, AADs have still an important role in the management of patients with recurrent AF without relevant heart disease, not only as first-line treatment, but also in patients who underwent catheter ablation. "
03/01/2017 - "Catheter ablation of ischemic VT appears effective and safe even in ≥75 year olds; however, extensive data for other structural heart diseases are lacking. "
05/01/1994 - "(1) Radiofrequency catheter ablation was considered to be effective and safe, especially for VT without underlying heart disease or VT originating from the right ventricle. "

08/01/2009 - "Our results suggest that recent decade brought significant improvement in the approach to secondary prevention of ischaemic heart disease in hospital practice."
07/29/2005 - "Current indications suggest that there is considerable room for improvement in the provision of secondary prevention for patients with established heart disease on the island of Ireland. "
01/01/2003 - "In 1998/99 compared with 1996/97 the quality of care in the field of secondary prevention of ischaemic heart disease was improved in cardiac departments of university and general hospitals in Cracow."
10/01/2020 - "In this study we analyse the relationship of all-cause mortality with meeting the objectives of secondary prevention of ischaemic heart disease in elderly patients. "
11/01/2016 - "In the present study, 24 patients (age 34.2 ± 11.5 years) with electrical heart disease or idiopathic VF received an S-ICD for primary (n = 8) or secondary prevention (n = 16). "

08/15/2019 - "The efficacy of interstitial vascular fraction (SVF) transplantation in the treatment of heart disease has been proven in a variety of in vivo studies. "
01/01/2018 - "The transplantation of beating cardiomyocytes (BCMs) is expected to be made more effective for serious heart diseases. "
09/20/2005 - "These results demonstrate the survival, feasibility, and safety of autologous myoblast transplantation and suggest that this modality offers a potential therapeutic treatment for end-stage heart disease."
01/01/2005 - "These interim results demonstrate survival, feasibility, and safety of autologous myoblast transplantation and suggest that this modality may offer a potential therapeutic treatment for end-stage heart disease."
09/01/2008 - "Delivery route should be selected according to the etiology of heart disease to optimize the efficacy of BMC transplantation."