Hallucinogens (Psychedelics)

Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.

Also Known As:

Networked: 173 relevant articles (4 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Javitt, Daniel C: 4 articles (10/2010 - 01/2007)
2.	Halberstadt, Adam L: 3 articles (11/2013 - 01/2011)
3.	González-Maeso, Javier: 3 articles (02/2011 - 03/2008)
4.	Nichols, Charles D: 3 articles (01/2009 - 05/2002)
5.	Sanders-Bush, Elaine: 3 articles (08/2007 - 05/2002)
6.	Kendler, Kenneth S: 2 articles (02/2016 - 03/2010)
7.	Bogenschutz, Michael P: 2 articles (03/2015 - 03/2013)
8.	Johnson, Matthew W: 2 articles (11/2014 - 09/2012)
9.	Griffiths, Roland R: 2 articles (11/2014 - 09/2012)
10.	Marin, Philippe: 2 articles (05/2014 - 01/2012)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 07/01/1998 - "Behavioral studies of hallucinogenic drugs in animals: implications for schizophrenia research." 11/01/2013 - "Serotonergic hallucinogens as translational models relevant to schizophrenia." 07/01/2013 - "The 5-HT₂A receptor mediates the effects of serotonergic hallucinogens and may play a role in the pathophysiology of certain psychiatric disorders, including schizophrenia. " 01/01/2013 - "This animal displays several schizophrenia-related behaviors, supersensitivity to hallucinogenic drugs and deficits in prepulse inhibition that reverse after antipsychotic treatment. " 08/01/2012 - "Ever using a drug was similar between the groups, except that significantly more participants with schizophrenia reported ever using hallucinogens (p<0.001) and inhalants (p=0.001). "
2.	Psychotic Disorders (Schizoaffective Disorder) 08/01/2008 - "Less common are prolonged psychoses triggered by hallucinogens. " 10/01/1996 - "It is contraindicated in patients with psychotic disorders, major depression, and abuse of hallucinogenic drugs. " 03/01/1995 - "Data were generated regarding hallucinogens' psychopharmacology, overlap with endogenous psychoses, and psychotherapeutic efficacy. " 01/01/1994 - "[The effect of hallucinogenic drugs on the development of psychoses]." 01/01/1989 - "The psychotomimetic paradigm, which viewed hallucinogens as agents for temporarily inducing psychoses, proved to be of limited value to the understanding and treatment of mental illness. "
3.	Headache (Headaches) 09/01/2012 - "DXM effects included increases in blood pressure, heart rate, and emesis; increases in observer-rated effects typical of classic hallucinogens (e.g., distance from reality, visual effects with eyes open and closed, joy, anxiety); and participant ratings of stimulation (e.g., jittery, nervous), somatic effects (e.g., tingling, headache), perceptual changes, end-of-session drug liking, and mystical-type experience. " 03/01/2013 - "Despite their legal status, hallucinogens and cannabinoids are used by patients for relief of headache, helped by the growing number of American states that have legalized medical marijuana. " 03/01/2013 - "The legal status of cannabinoids and hallucinogens has for a long time severely inhibited medical research, and there are still no blinded studies on headache subjects, from which we could assess true efficacy." 03/01/2013 - "Cannabinoids and hallucinogens for headache." 10/01/2012 - "Despite such classification, hallucinogens and cannabinoids are used by patients with headache on occasion. "
4.	Cluster Headache (Cluster Headaches) 11/01/2015 - "Findings provide additional evidence that several indoleamine hallucinogens are rated as effective in treating cluster headache. " 11/01/2015 - "Indoleamine Hallucinogens in Cluster Headache: Results of the Clusterbusters Medication Use Survey." 03/01/2013 - "Hallucinogens are being increasingly used by cluster headache patients outside of physician recommendation mainly to abort a cluster period and maintain quiescence for which there is considerable anecdotal success. " 10/01/2012 - "Hallucinogens are being increasing used by cluster headache patients outside of physician recommendation mainly to abort a cluster period and to maintain quiescence for which there is considerable anecdotal success." 03/01/2015 - "The range of recent clinical applications of psychedelics spans from cluster headaches and obsessive-compulsive disorder to addiction and the treatment of fear and anxiety in patients suffering from terminal illness, indicating potentially different therapeutic mechanisms. "
5.	Substance-Related Disorders (Drug Abuse) 04/01/2009 - "However, if we are to determine the mechanisms of action of these agents, establish hypotheses testable in human subjects, and explore the mechanistic links between hallucinogens and such apparently disparate topics as idiopathic psychosis, transcendental states, drug abuse, stress disorders, and cognitive dysfunction, studies in animals are essential. " 01/01/1985 - "In this study, 1,008 ninth grade boys and 1,040 ninth grade girls completed questionnaires concerning: (a) drug usage (alcohol, tobacco, marijuana, psychedelics, etc.) over the previous 6 months; and (b) outstanding performance in art, school subjects, music, leadership, performing arts, athletics, and writing. " 03/01/2015 - "Several lines of evidence suggest that classic (5HT2A agonist) hallucinogens have clinically relevant effects in alcohol and drug addiction. " 11/01/2014 - "Despite suggestive early findings on the therapeutic use of hallucinogens in the treatment of substance use disorders, rigorous follow-up has not been conducted. " 03/01/2013 - "The potential of psychedelics as a preventative and auxiliary therapy for drug abuse."

Related Drugs and Biologics

1.	Cannabinoids
2.	Lysergic Acid Diethylamide (LSD)
3.	Serotonin (5 Hydroxytryptamine)
4.	Amphetamines
5.	Heroin (Diamorphine)
6.	Cocaine (Cocaine HCl)
7.	Phencyclidine (Angel Dust)
8.	Crack Cocaine
9.	Dopamine (Intropin)
10.	Nitrites

Related Therapies and Procedures

1.	Therapeutics
2.	Prenatal Care