Guanidines

A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.

Networked: 29 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Casero, Robert A: 2 articles (09/2012 - 07/2010)
2.	Hanson, Allison S: 2 articles (09/2012 - 07/2010)
3.	Steinbergs, Nora: 2 articles (09/2012 - 07/2010)
4.	Woster, Patrick M: 2 articles (09/2012 - 07/2010)
5.	Luo, Xiaoqin: 1 article (06/2021)
6.	Song, Wangze: 1 article (06/2021)
7.	Wang, Aiguo: 1 article (06/2021)
8.	Zhang, Zhiyi: 1 article (06/2021)
9.	Zheng, Nan: 1 article (06/2021)
10.	Castagnolo, Daniele: 1 article (04/2021)

Related Diseases

1.	Edema (Dropsy) 01/01/1977 - "All substituted guanidines (50 mg/kg) provided 1-31% protection against carrageenin-induced edema in rats. "
2.	Neoplasms (Cancer) 12/08/2022 - "In this study, we investigated the effects of eleven synthetic guanidines containing the 1,3-diphenylpropenone core on the viabilities of six human cancer cells. " 08/27/2013 - "The synthesized guanidines were tested for antitumor activities against potato tumor, and showed excellent inhibition against Agrobacterium tumefaciens (AT10)-induced tumor. " 08/01/2012 - "Effect of substitution at N″-position of N'-hydroxy-N-amino guanidines on tumor cell growth." 07/22/2010 - "We recently reported a series of (bis)guanidines and (bis)biguanides that are potent inhibitors of LSD1 and induce the re-expression of aberrantly silenced tumor suppressor genes in tumor cells in vitro. " 12/08/2022 - "These synthetic guanidines are potent cytotoxic compounds against several human leukemia cells and even the human melanoma cell line SK-MEL-1 and might be useful in the development of new strategies in the fight against cancer."
3.	Tetany (Spasmophilia) 10/01/1924 - "The Parathyroids, Guanidines and Tetany." 01/01/1928 - "Guanidine studies: Distribution of guanidines in acute guanidine and parathyroprivia tetanies."
4.	Atherosclerosis 06/01/2004 - "In vitro study of the potential role of guanidines in leukocyte functions related to atherogenesis and infection."
5.	Infections 06/01/2004 - "In vitro study of the potential role of guanidines in leukocyte functions related to atherogenesis and infection."

Related Drugs and Biologics

1.	Carrageenan
2.	Guanidine (Guanidine Nitrate)
3.	Protein Isoforms (Isoforms)
4.	Biguanides
5.	Ceramidases
6.	Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)
7.	Small Interfering RNA (siRNA)
8.	3-Iodobenzylguanidine (Iobenguane)
9.	Nitric Oxide Synthase (NO Synthase)
10.	Collagenases (Collagenase)

Related Therapies and Procedures

1.	Precision Medicine
2.	Therapeutics