Glycogen Storage Disease Type VIII

An x-linked recessive hepatic glycogen storage disease resulting from lack of expression of phosphorylase-b-kinase activity. Symptoms are relatively mild; hepatomegaly, increased liver glycogen, and decreased leukocyte phosphorylase are present. Liver shrinkage occurs in response to glucagon.

Also Known As:

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Glycogen Storage Disease Type VIII:

1.	Peptide Hydrolases (Proteases)FDA Link 04/06/1992 - "The high molecular weight glycogen associated with the lysosomal compartment in glycogen storage disease type VIII is more resistant to degradation by proteinase than normal glycogen. "
2.	GlycogenIBA 04/06/1992 - "The high molecular weight glycogen associated with the lysosomal compartment in glycogen storage disease type VIII is more resistant to degradation by proteinase than normal glycogen. "