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Glutaral (Glutaraldehyde)

One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.

Also Known As:

Glutaraldehyde; Bioglan Brand of Glutaral; Bode Brand of Glutaral; Cahill May Roberts Brand of Glutaral; Cidex; Dermal Brand of Glutaral; Dermatech Brand of Glutaral; Diswart; Ecolab Brand of Glutaral; Gludesin; Glutardialdehyde; Glutarol; Johnson & Johnson Brand of Glutaral; Korsolex; Novaruca; Sekumatic; Sonacide; Sporicidin; Pentanedial

Networked: 931 relevant articles (38 outcomes, 79 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Suckow, Mark A: 5 articles (09/2008 - 06/2005)
2.	Wolter, William R: 4 articles (03/2008 - 06/2005)
3.	Duarte, Rafael Silva: 3 articles (10/2010 - 07/2009)
4.	Pitombo, Marcos Bettini: 3 articles (10/2010 - 07/2009)
5.	Timmerman, John M: 3 articles (03/2009 - 09/2008)
6.	Sailes, Valerie: 3 articles (09/2008 - 08/2007)
7.	Kieć-Swierczyńska, M: 3 articles (03/2001 - 01/2000)
8.	Guo, Lin: 2 articles (09/2015 - 12/2008)
9.	Koyama, Tadaaki: 2 articles (06/2015 - 06/2013)
10.	Fukunaga, Naoto: 2 articles (06/2015 - 06/2013)

Related Diseases

1.	Neoplasms (Cancer) 02/01/2006 - "Our study is the only one, to our knowledge, to examine cancer rates among exposed glutaraldehyde workers. " 12/01/1995 - "The study material consisted of glutaraldehyde-fixed, resin-embedded, semithin sections from 119 human tumors. " 08/01/1986 - "A few hamsters were perfused with glutaraldehyde for studies of tumor ultrastructure. " 06/01/2013 - "We report this case to show a successful result using glutaraldehyde-preserved bovine pericardium to close vascular defects after resection of the tumor secondary to vascular invasion. " 09/01/2008 - "Groups of ten rats were then vaccinated directly on the tumor bed with glutaraldehyde-treated tumor (GFT) cells harvested from a PAIII tumor; a 2 x 2 cm section of glutaraldehyde-treated SIS; or a 2 x 2 cm section of SIS on which harvested tumor cells were grown for either 3 days (GFT-S3) or 28 days (GFT-S28) and then treated with glutaraldehyde. "
2.	Hypersensitivity (Allergy) 01/01/2014 - "In the current study, we sought to improve our model by characterizing strain-associated differences in respiratory allergic reactions to the well-known chemical respiratory allergen glutaraldehyde (GA). " 09/01/1995 - "Respiratory peripheral sensory irritation and hypersensitivity studies with glutaraldehyde vapor." 12/01/2002 - "Equal percentages of workers in Kansas City and nationally had occupationally related allergy to glutaraldehyde, although the overall rate of glutaraldehyde was higher among patients from Kansas City. " 09/01/2000 - "Although the National Institute of Occupational Safety and Health has published guidelines for safe handling of glutaraldehyde, allergy appears to continue to rise, especially among those employed in health-care professions. " 09/01/1997 - "Non-occupational contact allergy to glutaraldehyde."
3.	Dehydration (Water Stress) 05/01/2001 - "Dehydration of tissue due to glutaraldehyde fixation has been reported and was examined in this study of porcine aortic valve cusps. " 05/01/2001 - "The significant effect of dehydration on cusp mechanical properties does not account for the effects observed after glutaraldehyde fixation, but it demonstrates that hydration level is an important factor that affects internal shear properties of valve cusps." 05/01/2001 - "Tissue dehydration also increased shear stiffness but increased stress relaxation and hysteresis, which was contrary to observations reported after glutaraldehyde fixation. " 03/01/1994 - "Common methods for preparing samples for immunoelectron microscopy involve glutaraldehyde fixation (GA) followed by chemical dehydration (CD) or cryofixation (CF) succeeded by physical dehydration, i.e., freeze drying (FD) or freeze substitution (FS). " 09/01/1992 - "Glutaraldehyde (GA) fixation for 2 hr and chemical dehydration was compared with short GA fixation (15 min) followed by cryofixation and freeze-drying (CF-FD). "
4.	Infection 07/01/1999 - "A 2.5% glutaraldehyde product was the most effective in halting excystation of sporozoites and infection in cell monolayers. " 11/01/2009 - "This study aimed at analysing the main factors linked to the recent RGM outbreaks, with focus on the national epidemic of Mycobacterium massiliense infections related to the BRA100 strains resistant to 2% glutaraldehyde commercial solutions commonly used for preoperative high-level disinfection. " 07/01/2015 - "More importantly, due to their intrinsic absorption of NIR light, glutaraldehyde-modified PEG-W18O49 are successfully applied as fault-free targeted photothermal agents for imaging-guided killing of bacteria on a mouse infection model. " 10/01/2010 - "Mycobacterium massiliense BRA100 strain recovered from postsurgical infections: resistance to high concentrations of glutaraldehyde and alternative solutions for high level disinfection." 07/01/2009 - "[Rapidly growing mycobacteria infection after videosurgical procedures - the glutaraldehyde hypothesis]."
5.	Cholera 06/01/1977 - "Protection against experimental cholera after immunization with a purified glutaraldehyde toxoid given subcutaneously (sc), orally, or by a combined sc-oral sequence was compared in dogs. " 11/01/1980 - "Ligated ileal loops of adult rabbits were used to evaluate the prophylactic potential against cholera of a combined vaccine consisting of toxin-free crude flagella (CF) and glutaraldehyde-derived cholera toxoid (TV). " 02/01/1974 - "At the same time, conditions are presented for the preparation of stable, antigenic cholera toxoids by reaction of purified toxin with glutaraldehyde. " 05/01/1979 - "In the study reported here, two different biologically inactive but antigenically intact cholera toxoids, glutaraldehyde toxoid and choleragenoid, where administered s.c. "

Related Drugs and Biologics

1.	Antigens
2.	Bio-glue
3.	Tissue Adhesives (Tissue Adhesive)
4.	Allergens
5.	Glutaral (Glutaraldehyde)
6.	maleimide
7.	Formaldehyde (Formol)
8.	Collagen
9.	Tyrosine (L-Tyrosine)
10.	Ethanol (Ethyl Alcohol)

Related Therapies and Procedures

1.	Injections
2.	Transplants (Transplant)
3.	Immunotherapy
4.	Mastectomy (Mammectomy)
5.	Lasers (Laser)