Glucans

06/01/2013 - "This review focuses on human studies; clinical trials and epidemiological data assessing the efficacy and safety of mushroom-derived β- glucans in cancer treatment and prevention. "
06/01/2013 - "β-Glucans and their applications in cancer therapy: focus on human studies."
06/01/2013 - "Recent advance in the studies of β-glucans for cancer therapy."
10/01/2015 - "Our findings provide novel mechanistic insights into their antiproliferative roles, and compelling evidence that these β-glucans possess a broad range of biomodulatory properties that may prove useful in cancer treatment. "
10/01/2015 - "Fungal β-d-glucans of the (1→3)-type are known to exhibit direct antitumor effects, and can also indirectly decrease tumor proliferation through immunomodulatory responses. "

01/01/2014 - "Three groups were inoculated with Pasteurella multocida intranasally (in.), a physiologically appropriate challenge which reproduces naturally acquired infection, and received either (1-3), (1-6) β-glucans or placebo. "
01/01/2014 - "Effect of treatment of chum salmon Oncorhynchus keta (Walbaum) eggs with 1,3;1,6-β-D-glucans on their development and susceptibility to Saprolegnia infection."
10/01/2013 - "Administration of glucans through immersion, dietary inclusion or injection has been found to enhance many types of immune responses, resistance to bacterial and viral infections and to environmental stress in many fish species. "
09/01/2012 - "Fungal and particulate β-glucans, despite their large size, can be taken up by the M cells of Peyer's patches, and interact with macrophages or dendritic cells (DCs) and activate systemic immune responses to overcome the fungal infection. "
05/01/2011 - "β-Glucans are generally safe and are known to attenuate the rate of postoperative infection. "

12/01/2015 - "However, no significant differences in other clinical colitis scores between soluble and particulate β-glucans were found in this study. "
02/01/2010 - "The aims of the present study were to determine whether orally administered glucans from the edible mushroom Pleurotus pulmonarius could attenuate or prevent the development of experimental colitis in mice. "
01/01/2014 - "Effect of glucans from Caripia montagnei mushroom on TNBS-induced colitis."
05/01/2012 - "Glucans from the edible mushroom Pleurotus pulmonarius inhibit colitis-associated colon carcinogenesis in mice."
02/01/2010 - "pulmonarius glucans attenuated and prevented the development of symptoms associated with DSS-induced colitis. "

01/01/2010 - "Glucan extracts from the Trametes versicolor mushroom improved survival and immune function in human RCTs of cancer patients; glucans, arabinogalactans and fucoidans elicited immunomodulatory effects in controlled studies of healthy adults and patients with canker sores and seasonal allergies. "
07/01/2012 - "In later studies, β(1→3)glucans, extracellular polysaccharides, and muramic acid from, respectively, molds and gram-positive bacteria were associated with a reduced risk of allergy and asthma separately in rural and urban populations. "

07/01/2015 - "Accordingly, we sought to characterize β-1,6 glucans in the cell wall of Pneumocystis and to establish their activity in lung cell inflammation. "
05/01/2012 - "Pre-incubation of THP-1 macrophages with β-glucans prior to lipopolysaccharide (LPS) exposure decreased the induction of inflammation-related genes compared to LPS treatment. "
05/01/2012 - "All tested β-glucans mildly upregulated the observed inflammation-related genes with differential gene expression patterns. "
02/01/2014 - "We can summarize that oral consumption of several mushrooms glucans is an efficient treatment to prevent colitis-associated dysplasias through modulation of mucosal inflammation and cell proliferation. "
03/01/2007 - "The results demonstrated that water-soluble alpha-glucans modulate macrophage- and granulocyte-induced inflammatory immune responses, and suggest that inflammation induced by those alpha-glucans is associated with the development of periodontal diseases."