Glaucarubin

(1 beta,2 alpha,11 beta,12 alpha,15 beta(S))-11,20-Epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)picras-3-en-16-one. A quassinoid (Simaroubolide) from Simaruba glauca, a tropical shrub. It has been used as an antiamebic agent and is found to be cytotoxic. It may be of use in cancer chemotherapy.

Also Known As:

Kirondrin; Picras-3-en-16-one, 11,20-epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)-, (1beta,2alpha,11beta,12alpha,15beta(S))-

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Amebic Dysentery (Amoebic Dysentery) 03/22/1963 - "[The treatment of intestinal amebiasis with glaucarubin. " 08/08/1959 - "[The treatment of intestinal amebiasis by glaucarubin]." 03/01/1956 - " II. The treatment of intestinal amoebiasis with emetine bismuth iodide, glaucarubin, dichloroacet-hydroxy-methylanilide, camoform and various antibiotics."
2.	Amebiasis (Amoebiasis) 08/01/1962 - "[Treatment of autochthonous chronic non-dy-senteric amebiasis with glaucarubin]." 03/01/1956 - "Clinical trial of glaucarubin in treatment of amebiasis." 05/01/1956 - "The use of glaucarubin (a crystalline glycoside isolated from Simarouba glauca) in the treatment of human colonic amebiasis."

Related Drugs and Biologics

1.	Glycosides
2.	Emetine
3.	Anti-Bacterial Agents (Antibiotics)
4.	bismuth iodide