Absorbable Gelatin Sponge

Sterile, gelatin-base surgical sponge applied topically as an adjunct to hemostasis when the control of bleeding by conventional procedures is ineffective to reduce capillary ooze or is impractical. (From AMA Drug Evaluations Annual, 1994, p797)

Also Known As:

Networked: 604 relevant articles (29 outcomes, 45 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Hoffman, Robert M: 6 articles (08/2014 - 05/2002)
2.	Weaver, Fred A: 4 articles (01/2010 - 05/2002)
3.	Li, Jian-Jun: 2 articles (03/2015 - 01/2006)
4.	Wang, Hong-Hui: 2 articles (01/2015 - 01/2006)
5.	Xu, Wei: 2 articles (01/2015 - 01/2006)
6.	Bai, Bin: 2 articles (01/2015 - 01/2006)
7.	Bouvet, Michael: 2 articles (08/2014 - 01/2014)
8.	Yano, Shuya: 2 articles (08/2014 - 01/2014)
9.	Uehara, Fuminari: 2 articles (08/2014 - 01/2014)
10.	Yang, Jian: 2 articles (10/2011 - 10/2004)

Related Diseases

1.	Hemorrhage 07/01/2007 - "Analysis of the results demonstrated that the haemostatic agents are effective in controlling hemorrhage; they stimulate osteogenesis, featuring a pattern of osseous tissue formation similar to the control pattern, although the amount of osseous trabeculae was superior, especially in the Gelfoam group in the periods of 7 and 14 days; 30 days after surgery, the delay in tissue healing in the control group in relation to the experimental groups started to decrease, and the control and experimental groups exhibited similar tissue repair after 45 days, when all the groups exhibited secondary osseous tissue." 12/01/1981 - "In 16 patients, gelfoam embolization of the bronchial artery was effective in causing immediate cessation of the hemorrhage. " 08/01/2006 - "The insertion of an absorbable gelatin sponge into the extraction socket was found to be a very useful method to prevent postoperative bleeding problems." 08/01/2007 - "Blinded study drug was applied topically to bleeding sites with an absorbable gelatin sponge. " 05/01/1987 - "Following a pilot study a controlled trial was carried out to assess the effect of absorbable gelatin sponge on reducing the bleeding from microvascular anastomoses of the femoral arteries and veins of rats. "
2.	Neoplasms (Cancer) 03/14/2015 - "If new HCC lesions were confirmed, gelfoam particles were super-selectively injected into the tumor-nourishing blood vessel. " 01/01/2015 - "Gelfoam embolization or 125I seed implantation may be a more effective treatment than surgical treatment for giant benign sacral neurogenic tumors." 12/21/2014 - "Eight tumors in patients with a large amount of blood loss were treated with transcatheter arterial embolization with gelfoam particles during interventional DSA. " 08/01/2014 - "When the cancer cells were seeded on Gelfoam(®), the cells formed three-dimensional tissue-like structures. " 01/01/2014 - "Pre-operative percutaneous selective catheterizations of the arteries feeding the metastatic tumors were performed, followed by infusion of gelfoam. "
3.	Fibrosis (Cirrhosis) 04/01/2009 - "The Gelfoam group was associated with the best outcome with regard to the number of engrafted donor cells (p = 0.03 versus myoblasts) and the reduction of fibrosis (p = 0.02 and p = 0.04 versus the control and myoblast groups, respectively). " 04/01/1997 - "Although the sponge is generally well tolerated, fibrosis occasionally forms in the mesotympanum; some studies indicated that the absorbable gelatin sponge may be responsible. " 05/01/2014 - "The absorbable gelatin sponge is the most widely used, but it may produce fibrosis and impair ventilation of the middle ear. " 02/01/2014 - "Gelfoam gave similar results to SFS and ACS after SC implantation, but it was found to be associated with pronounced fibrosis and osteoneogenesis after ME implantation. " 06/01/1990 - "Gelfoam did not inhibit but actually appeared to increase fibrosis formation. "
4.	Wounds and Injuries (Trauma) 12/01/2014 - "The aim of this study is to compare the effects of the absorbable gelatin sponge (AGS), microporous polysaccharide hemospheres (MPH), and Ankaferd on wound healing after middle ear trauma and to evaluate their ototoxicity in an experimental guinea pig model. " 11/08/1996 - "In this study we report on the in vitro effects of extracts (obtained from gelfoam) removed from striatal cavities 7 days following trauma. " 02/01/1948 - "Further studies of gelfoam in kidney wounds; the effect of urinary wetting." 04/01/2015 - "However, gelfoam is the only commercially available biodegradable embolic material used to treat blunt trauma of solid abdominal viscera until now, and controversial on its stability and reliability never stopped in the past five decades. " 12/01/2014 - "In the group B with the mean INR of 2.43 ± 0.4, local hemostasis was achieved by placing absorbable gelatin sponges into the wound without suturing. "
5.	Dry Socket (Alveolar Osteitis) 01/01/1990 - " Absorbable gelatin sponge alone is not effective in reducing the incidence of alveolar osteitis. " 01/01/1992 - "This double blind clinical study was undertaken to evaluate the effectiveness of locally applied clindamycin in Gelfoam in reducing the incidence of dry socket formation after third molar surgery. " 08/01/1988 - "This clinical study was undertaken to evaluate the effectiveness of locally applied 9-aminoacridine in Gelfoam in reducing the incidence of dry socket formation after third molar extractions. " 08/01/1988 - "An evaluation of 9-aminoacridine/Gelfoam to reduce dry socket formation." 05/01/1982 - "Prevention of dry socket with local application of Terra-Cortril in gelfoam."

Related Drugs and Biologics

1.	Gelatin
2.	Fibrin Tissue Adhesive (Fibrin Sealant)
3.	Bupivacaine (Bupivacaine Hydrochloride)
4.	gelatin film
5.	Thrombin
6.	Ethiodized Oil (Ethiodol)
7.	Polyvinyl Alcohol
8.	Surgicel
9.	Carboplatin (JM8)
10.	Collagen

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Microspheres (Microsphere)
3.	Cesarean Section (Caesarean Section)
4.	Nephrectomy
5.	Balloon Occlusion