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Gas Gangrene (Gangrene, Gas)

A severe condition resulting from bacteria invading healthy muscle from adjacent traumatized muscle or soft tissue. The infection originates in a wound contaminated with bacteria of the genus CLOSTRIDIUM. C. perfringens accounts for the majority of cases (over eighty percent), while C. noyvi, C. septicum, and C. histolyticum cause most of the other cases.
Also Known As:
Gangrene, Gas; Gangrenes, Gas; Gas Gangrenes
Networked: 589 relevant articles (20 outcomes, 24 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Infections
2. Wounds and Injuries (Trauma)
3. Carbon Monoxide Poisoning (Poisoning, Carbon Monoxide)
4. Osteomyelitis
5. Ulcer

Experts

1. Rood, Julian I: 11 articles (02/2020 - 02/2000)
2. Nagahama, Masahiro: 10 articles (10/2020 - 01/2002)
3. Cheung, Jackie K: 10 articles (02/2020 - 02/2000)
4. Ohtani, Kaori: 9 articles (01/2019 - 04/2002)
5. Shimizu, Tohru: 8 articles (05/2018 - 04/2002)
6. Flores-Díaz, Marietta: 8 articles (04/2014 - 12/2003)
7. Awad, Milena M: 7 articles (01/2022 - 04/2002)
8. Sakurai, Jun: 7 articles (12/2015 - 01/2002)
9. Alape-Girón, Alberto: 7 articles (04/2014 - 12/2003)
10. Titball, Richard W: 7 articles (10/2012 - 05/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Gas Gangrene:
1. Oxygen (Dioxygen)IBA
2. Anti-Bacterial Agents (Antibiotics)IBA
3. Rifampin (Rifampicin)FDA LinkGeneric
4. Penicillins (Penicillin)FDA Link
5. Clindamycin (Cleocin)FDA LinkGeneric
6. AntitoxinsIBA
7. VaccinesIBA
8. ToxoidsIBA
9. Penicillin G (Benzylpenicillin)FDA LinkGeneric
10. Deoxyribonuclease I (Nickase)IBA

Therapies and Procedures

1. Therapeutics
2. Hyperbaric Oxygenation
3. Surgical Amputation (Amputations)
4. Debridement
5. Critical Care (Surgical Intensive Care)