Gallic Acid

12/01/2013 - "Here, we have developed an improved chemical synthesis for DEL in order to study the effects of the aglycon and its degradation product gallic acid (GA) on endothelial and tumor cells in vitro and in vivo. "
07/01/2015 - "The aim of this study was to evaluate the lytic peptide Hecate (FALALKALKKALKKLKKALKKAL) and the effect of conjugating this macromolecule with gallic acid (C7H6O5) in terms of structure, anti-cancer activity, and toxicity. "
10/01/2013 - "Our earlier studies have demonstrated that gallic acid (GA) induced cytotoxic effects including induction of apoptosis and DNA damage and inhibited the cell migration and invasion in human cancer cells. "
12/28/2009 - "In this study, gallic acid is identified as the major anti-cancer compound in T. "
11/01/2001 - "The present study further investigated the in vivo anti-tumor effects of orally administered gallic acid. "

04/01/2014 - "The administration of gallic acid at three dose levels offered a significant protection against renal ischemia-reperfusion-induced AKI. "
01/01/2014 - "The examination of protective effects of gallic acid against damage of oxidative stress during induced-experimental renal ischemia-reperfusion in experiment."
06/01/2014 - "The aim of this study was to determine the combined effect of gallic acid and CsA on antioxidant capacity of isolated heart tissues during ischemia reperfusion. "
10/01/2015 - "There is little information about the hepatoprotective effects of gallic acid against ischemia-reperfusion (I/R) damage. "
01/01/2014 - "Gallic acid was given 15 mins before ischemia induction. "

09/01/2014 - "While platelet reactivity was not altered by HUVECs incubated with higher concentrations of GSE, HUVEC proliferation was significantly reduced by GSE of up to 10 μg gallic acid equivalent/ml. The results of the study show that low doses of GSE potentiate the inhibitory action of HUVECs on platelet reactivity, which may account, at least partially, for the protective effects of grape products against cardiovascular diseases. "
03/01/2015 - "In this study, we investigated the vasorelaxant and antihypertensive effects of gallic acid (GA), a polyphenol isolated from the green alga Spirogyra sp., to assess its suitability as a therapeutic for cardiovascular diseases (CVDs). "
03/01/2015 - "Gallic acid isolated from Spirogyra sp. improves cardiovascular disease through a vasorelaxant and antihypertensive effect."
07/01/2015 - "Gallic acid (GA), one of the main phenolic components, has been a subject of increasing interest due to their biological properties, including anti-inflammatory, antihistaminic, and antitumor activities, scavenging of free radicals, and protecting against cardiovascular diseases. "
02/26/2014 - "Gallic acid (GA), a chemically unique phenolic acid with important biological functions, presents benefits to the cardiovascular disease therapy because of its superior antioxidant effect and a selectivity to support the growth of ECs more than SMCs. "

03/01/2007 - "The objective of this study was to test the safety and efficacy of NT, a dietary herbal supplement made from rhubarb, ginger, astragulus, red sage, and turmeric, combined with gallic acid (GA) to reduce food intake and cause weight loss. "
03/01/2007 - "The safety and efficacy of a dietary herbal supplement and gallic acid for weight loss."
12/01/2006 - "Number Ten was found to contain sennosides, known laxatives and gallic acid, which is known to give weight loss in rodents. "
01/01/2011 - "Gallic acid glycerol ester promotes weight-loss in rats."
01/01/2012 - "We previously fed rats with an ester (90 ppm in a powdered AIN93G diet) synthesized from gallic acid and 1,2-dioleoyl glycerol and found that it promoted weight loss more effectively than either octyl gallate or gallic acid. "

12/28/2009 - "Taken together, our results suggest that gallic acid has the potential to be developed into an anti-prostate cancer drug and is worthy of further studies."
10/01/2013 - "Gallic acid provokes DNA damage and suppresses DNA repair gene expression in human prostate cancer PC-3 cells."
05/01/2012 - "Gallic acid (GA) is a natural polyphenol, and we tested its in-vitro cytotoxicity after 24 h in prostate cancer LNCaP cells. "
05/01/2012 - "Autoxidation of gallic acid induces ROS-dependent death in human prostate cancer LNCaP cells."
12/01/2006 - "Together, this is the first report identifying gallic acid efficacy and associated mechanisms in an advanced and androgen-independent human prostate carcinoma DU145 cells, suggesting future in vivo efficacy studies with this agent in preclinical prostate cancer models."