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Galactorrhea

Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA.
Also Known As:
Galactorrheas
Networked: 770 relevant articles (31 outcomes, 49 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Amenorrhea
2. Hyperprolactinemia
3. Gynecomastia
4. Neoplasms (Cancer)
5. Pituitary Neoplasms (Pituitary Adenoma)

Experts

1. Molitch, Mark E: 3 articles (01/2021 - 06/2012)
2. Mancano, Michael A: 3 articles (04/2019 - 04/2015)
3. Jiloha, R C: 3 articles (06/2016 - 01/2004)
4. Mendhekar, D N: 3 articles (03/2005 - 01/2004)
5. Grohmann, R: 2 articles (12/2021 - 03/2004)
6. Huang, Wenyu: 2 articles (01/2021 - 06/2012)
7. Kelly, Deanna L: 2 articles (08/2018 - 04/2006)
8. Gunes, Serkan: 2 articles (01/2018 - 08/2017)
9. Nebhinani, Naresh: 2 articles (01/2018 - 09/2013)
10. Ceylan, Mehmet Emin: 2 articles (01/2016 - 06/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Galactorrhea:
1. ProlactinIBA
2. Bromocriptine (Parlodel)FDA LinkGeneric
3. Antipsychotic Agents (Antipsychotics)IBA
4. Pergolide (Permax)FDA Link
5. Sertraline (Zoloft)FDA LinkGeneric
6. Amantadine (Aman)FDA LinkGeneric
7. Testosterone (Sustanon)FDA Link
05/15/1978 - "Amenorrhea-galactorrhea associated with a testosterone-producing, solid granulosa cell tumor."
04/01/2004 - "At study entry, of the 41 patients with macroprolactinoma, 17 (41.4%) had visual field defects, 14 (34.1%) had headache, eight (19.5%) had galactorrhea, 22 (53.6%) had hypopituitarism apart from hypogonadism, and 30 (73.2%) had low testosterone levels; of the 10 patients with microprolactinoma, none had visual field defects, galactorrhea, or hypopituitarism apart from hypogonadism, two had headache (20%), and five had low testosterone levels (50%; P = 0.3). "
12/01/2002 - "Male hyperprolactinemia can cause hypogonadism (decreased testosterone levels), libido decrease, infertility due oligospermia and gynecomastia while galactorrhea rarely occurs. "
10/01/1977 - "The plasma prolactin was increased to 58 ng/ml and rose to 97 ng/ml after 200 microgram TRF iv. The patient was treated for one year with testosterone; his voice deepened, body hair developed, libido and sexual function became overt, and bone age advanced from 14 1/2 to 17 years, but the galactorrhea increased. "
06/01/2006 - "After switching to olanzapine treatment, male patients experienced significantly (p=.03) increased free testosterone levels but there were no significant improvements in total testosterone levels; some female patients experienced improved menstrual cycling, as well as resolution of galactorrhea and gynecomastia, and sexual functioning was significantly improved in both genders. "
8. Olanzapine (Zyprexa)FDA Link
9. Quetiapine Fumarate (Seroquel)FDA Link
10. Pyridoxine (Pyridoxin)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Aftercare (After-Treatment)
3. Drug Therapy (Chemotherapy)
4. Mammaplasty (Breast Reconstruction)
5. Radiotherapy