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G(M3) Ganglioside

A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.
Also Known As:
Ganglioside GM3; II3NeuAcLacCer; Sialyl Lactosylceramide; GM3, Ganglioside; Lactosylceramide, Sialyl; Hematoside; Sialyllactosylceramide
Networked: 223 relevant articles (3 outcomes, 13 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kabayama, Kazuya: 8 articles (01/2020 - 02/2002)
2. Carr, Adriana: 8 articles (06/2019 - 01/2011)
3. Blanco, Rancés: 7 articles (06/2019 - 01/2011)
4. Kim, Cheorl-Ho: 7 articles (01/2018 - 07/2006)
5. Lee, Young-Choon: 7 articles (01/2018 - 07/2006)
6. Rengifo, Charles E: 7 articles (01/2015 - 01/2011)
7. Rengifo, Enrique: 7 articles (01/2015 - 10/2004)
8. Inokuchi, Jin-Ichi: 6 articles (01/2022 - 01/2005)
9. Paller, Amy S: 6 articles (01/2018 - 12/2006)
10. Cedeño, Mercedes: 6 articles (01/2015 - 01/2011)

Related Diseases

1. Experimental Melanoma
2. Mucolipidoses (Sialidosis)
3. Lewis Lung Carcinoma
4. Neoplasms (Cancer)
5. Insulin Resistance

Related Drugs and Biologics

1. N-Acetylneuraminic Acid (Sialic Acid)
2. Glucosylceramides (Glucocerebrosides)
3. Vaccines
4. CDw17 antigen (lactosylceramide)
5. RV 538 (PDMP)
6. ceramide trihexoside
7. Glycolipids
8. Monoclonal Antibodies
9. Lipids
10. haematoside synthetase

Related Therapies and Procedures

1. Immunotherapy
2. Therapeutics